The Sensitivity Doctor

The Neurobiology of Breakups: How to Move On & Go No Contact with Cole Zesiger


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In this compassionate and eye-opening episode, Amelia sits down with breakup and relationship coach Cole Zesiger, who has helped millions online learn how to navigate heartbreak with clarity, emotional safety, and self-respect. Cole shares the deeply personal story of his early divorce, the patterns of anxious attachment that shaped his relationships, and the unexpected journey that led him to rebuild his life and help thousands do the same.

Together, Amelia and Cole break down why breakups feel neurologically like withdrawal, what “euphoric recall” has to do with your ex, why the holidays intensify loneliness, and how to make the no-contact rule actually work without feeling like you are losing your mind. Cole also explains the biggest mistakes people make right after a breakup, the surprising science behind why your brain becomes obsessed with your ex, and how to rebuild a life that feels bigger, safer, and more meaningful than the one you are grieving.

Whether you are in the early shock, the confusing in-between, or trying to stop the cycle of “one more text,” this episode offers compassionate insight, grounded strategies, and the hope you might not realize you need right now.


Key Takeaways:

  • Why your brain treats heartbreak like survival mode and how evolutionary wiring makes you want to chase your ex even when you logically know better.
  • The real reason no-contact is so hard and how to create a plan that protects your emotional and neurological energy.
  • What euphoric recall is and why your brain only replays the good memories plus how to ground yourself in the full truth of the relationship.
  • How to rebuild your life after a breakup by focusing on the pillars that shape your sense of identity, connection, and purpose.
  • Why the holidays intensify heartbreak and practical ways to lean on safe relationships, structure, and self-compassion to get through the season.


Connect with Cole Zesiger:

Website: coachcolezesiger.com

Instagram: @coachcolezesiger

TikTok: @colezesiger

YouTube: Cole Zesiger

Book: Exes & No’s - available for pre-order (bonus course included)


Connect with Dr. Amelia Kelley: About | Dr. Kelley's Books Instagram 



Support this podcast at — https://redcircle.com/the-sensitivity-doctor/exclusive-content
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The Sensitivity DoctorBy Dr. Amelia Kelley

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