GLP-1 Medications: Efficacy, Safety, and Impact

Read our companion blog post with visuals on this episode

This comprehensive analysis examines the impact of GLP-1 receptor agonists on health, particularly their significant efficacy in weight loss and treatment of diabetes. It highlights studies demonstrating the superior performance of newer dual-agonist medications like Zepbound compared to Wegovy, while also outlining the common gastrointestinal side effects and less frequent but more serious adverse events. Beyond metabolic improvements, the sources explore the expanding therapeutic benefits of GLP-1s, including cardiovascular protection, reduction in addiction behaviors, and positive effects on sleep apnea, kidney function, and even neurological health. Finally, the analysis discusses the rapid adoption of these medications in the U.S. amidst a national obesity and diabetes crisis, noting the high financial burden and existing disparities in access.