The Obesity Guide with Matthea Rentea MD

Your Friday Five: When Health Gains Meet Hair Fears


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Hair loss is one of the most common fears people bring up when considering GLP-1 medications—especially women in menopause whose hair is already feeling thin, fragile, or vulnerable. This week’s Friday Five dives into the actual conversation you should be having before you make any decisions.

In this short episode, I unpack why there is no one-size-fits-all answer to “Will I lose more hair?” and why it requires a real clinical evaluation. But more importantly, I walk you through the two essential steps anyone worried about hair loss should take.

Here’s what we cover:

  1. Why the “risk vs. benefit” conversation matters more than the internet does
    Hair thinning is a real risk—and for some women, it’s a deeply emotional one. This isn’t superficial or silly. But the question to sit with is:
    Do the potential health benefits outweigh this risk for me?
  2. Why hair loss varies wildly
    Some people lose none.
    Some lose a lot.
    Some lose slowly and never notice.
    Others lose slowly and still see big changes.
    This variability is exactly why you can’t predict it without personalized care.
  3. Why dermatology needs to be part of the plan—GLP-1 or not
    If hair loss is already a concern, don’t wait.
    There are evidence-based treatments—oral, topical, supplement-based—but they need to fit your medical history.
    A dermatologist can get you started before you ever step on a GLP-1.
  4. How focusing too much on aesthetics steals your joy
    Loose skin, wrinkles, thinning hair—all part of the process of being human.
    But letting them take the wheel derails the bigger picture: your long-term health, your energy, your quality of life.
    We talk through why it matters to stay anchored to your North Star.
  5. Why you’re not meant to make these decisions alone
    So many people are trying to assess risk in isolation.
    Please don’t.
    Talk to your physician. Talk to a dermatologist. Build a real plan—not a fear-based one.

If hair thinning is something you’re afraid of, this episode will ground you, normalize the concern, and give you a clear next step.

See you Monday.

All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com

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The Obesity Guide with Matthea Rentea MDBy Matthea Rentea MD

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