Rooted in Wellness with Mona Sharma

54. The Hidden Gut Fix for Fatigue, Cravings, and Weight Gain with Colleen Cutcliffe


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What if the brain fog, sugar cravings, and stubborn fatigue you’re feeling… starts in your gut?
In this eye-opening episode, I sit down with Dr. Colleen Cutcliffe—Stanford PhD scientist and co-founder of Pendulum Therapeutics—to unpack the real reasons so many of us struggle with metabolic health, mood imbalances, and digestion. We explore how your gut microbiome shapes your energy, hormones, and weight every single day—even if the root cause began years ago.
We break down the rise of leaky gut, the missing bacteria like Akkermansia that most probiotics ignore, and science-backed steps to start healing from within.
If you’ve tried everything and still feel off, this conversation offers clarity—and real hope.
Dr. Colleen Cutcliffe is a microbiome expert, Stanford PhD, and CEO of Pendulum Therapeutics.
We Also Discuss:
03:55 – When I realized my heart issues weren’t just physical
10:35 – How your gut is secretly running the show
15:54 – Yep… people are healing with poop transplants
24:52 – What antibiotics in childhood did to my metabolism
31:09 – Why your probiotic might be doing nothing
45:42 – The one gut strain you need (and probably don’t have)
57:07 – I stopped craving sugar—here’s what changed
01:05:08 – Before you try Ozempic…listen to this about your gut

Thank You to Our Sponsors:

12 Tips: Ready to feel energized, focused, and vibrant—starting today? Download 12 Wellness Tips to Awaken Your Best Health and start transforming your body and mind now: 👉 https://www.monasharma.com/12tips
Rooted Academy: Join Rooted Academy by Mona Sharma, a science-backed, community-driven wellness platform designed to help you heal from within. Start your journey to balance, vitality, and lasting transformation. https://www.monasharma.com/rooted

Learn more about Mona Sharma:

Download Your FREE Guide - 12 Wellness Tips to Unlock Your Best Health Now: Ready to reclaim your vitality? Download Mona’s 12 Wellness Tips and take actionable steps to transform your health, energy, and mindset. Get started now at https://monasharma.com/12tips.
Visit Mona's website: https://monasharma.com – Unlock powerful tools and wisdom rooted in wellness to elevate your health, energy, and clarity. Mona blends ancient healing practices with modern science to help you achieve lasting transformation.
Follow Mona on Instagram: Stay connected with Mona for daily inspiration, holistic health tips, and personal growth. Join the conversation on Instagram at https://instagram.com/monasharma.

Learn more about Colleen Cutcliffe:

Website: https://pendulumlife.com/
Instagram: @pendulumlifeco
Instagram: @drcolleencutcliffe/

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Rooted in Wellness with Mona SharmaBy Mona Sharma

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