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Nick talks to biochemist Joe Baur, PhD, whose lab at the University of Pennsylvania studies the molecular mechanisms of aging and metabolism. They discuss: aging as a passive vs. regulated process; mechanisms of aging (DNA mutations, oxidative stress, etc.); NAD and its role in normal physiology; the biology of sirtuins; rapamycin as an immunosuppressant & modulator of aging; the effects of diet & caloric restriction on aging; the potential slowing and reversing aging, and more.
*Not medical advice.
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All episodes, show notes, transcripts, and more at the M&M Substack
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For all the ways you can support my efforts
4.8
7373 ratings
Send us a text
Nick talks to biochemist Joe Baur, PhD, whose lab at the University of Pennsylvania studies the molecular mechanisms of aging and metabolism. They discuss: aging as a passive vs. regulated process; mechanisms of aging (DNA mutations, oxidative stress, etc.); NAD and its role in normal physiology; the biology of sirtuins; rapamycin as an immunosuppressant & modulator of aging; the effects of diet & caloric restriction on aging; the potential slowing and reversing aging, and more.
*Not medical advice.
Support the show
All episodes, show notes, transcripts, and more at the M&M Substack
Affiliates:
For all the ways you can support my efforts
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