Could improving your sleep actually protect your brain and prevent Alzheimer’s? In today’s episode, I interview Dr. Sahil Chopra, a leading expert in sleep medicine and founder of Empower Sleep, to explore sleep as one of the most powerful tools for brain health.

Dr. Chopra shares why measuring your sleep is essential, how modern home sleep studies give more accurate data than ever before, and practical strategies for improving both sleep quality and circadian rhythm. 

We discuss the role of REM and deep sleep in memory consolidation, amyloid clearance, and cognitive longevity. You’ll also learn when melatonin can be helpful, how caffeine affects sleep differently for everyone, and why personalized approaches matter more than generic advice.

If you’re ready to optimize your sleep and support your brain, this episode is a must-listen.

This episode is sponsored by Organifi

- Get 20% off organic superfood blends at www.organifi.com/DRJOSH with code DRJOSH

“If you make sleep better, all of the other things get better, particularly brain health.” 

~ Dr. Sahil Chopra

In this Episode

05:25 - Sleep’s role in brain health: glymphatic system and waste clearance

10:02 - REM vs. deep sleep: impact on memory and emotional health

13:15 - Circadian rhythm disruption and catching up on sleep

15:41 - Melatonin: when it helps and when to avoid

19:35 - Advances in at-home sleep studies and wearable devices

28:14 - Tracking sleep patterns and the effect of stimulants for better sleep 

33:52 - Sleep hygiene and habits for better brain health

37:06 - The future of sleep medicine: AI and technology integration

40:20 - How to work with Dr. Chopra and participate in sleep studies

50:29 - Key takeaways from this sleep and brain health conversation

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

Connect with Dr. Sahil Chopra: 

- Website - https://www.empowersleep.com/

- Instagram - https://www.instagram.com/empowersleep/

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

Could one of the smallest molecules in the universe hold the key to reversing Alzheimer's and cognitive decline? Today's guests share groundbreaking insights into the power of hydrogen gas and its potential to transform brain health.

I had the pleasure of interviewing Dr. Greg Carder and Mick Emandi, pioneers in the field of hydrogen therapy for brain health. We dive into how molecular hydrogen may play a role in preventing and even reversing conditions like Alzheimer’s and Parkinson’s. What’s truly remarkable is how this simple molecule, when administered at the correct dosage, can power up mitochondria, reduce inflammation, and promote brain cell regeneration. 

Whether you're looking to improve cognitive function or prevent neurodegenerative diseases, this episode holds a world of potential. Stay tuned, and don’t miss out on the innovative therapies that could transform brain health for the better.

For more information, visit https://www.hydroheal.com/ and use the following codes to get a discount:

-ALZ600 - $500 off HH600

-ALZ300 -  $250 off HH300

“I like to call molecular hydrogen the only performance-enchancing drug that's not a drug. By supplying your body in general and your mitochondria specifically with this super fuel, you are enhancing your body's performance along resistance and cardiovascular levels almost immediately.” 

~ Dr. Greg Carder

In this Episode

04:04 - Molecular hydrogen and how it helps our health

06:16 - Hydrogen vs. traditional antioxidants

11:52 - Hydrogen for Alzheimer’s & Parkinson’s: which countries are ahead?

22:38 - Who would not benefit from hydrogen therapy?

24:10 - Natural sources of hydrogen

36:27 - Preventive benefits of hydrogen therapy

42:07 - Real-world results of hydrogen therapy

44:01 - Hydrogen + stem cells for brain regeneration

49:26 - How hydrogen therapy benefits the brain

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

Connect with Dr. Greg Carder & Mick Emandi: 

- Website - https://www.hydroheal.com/

- Instagram - instagram.com/hydroheal/#

- Phone Number (Mick) - (212) 777-0187

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

What if the key to preventing or even reversing Alzheimer’s isn’t in a pill, but in what you put on your plate? In this episode, I interview Dr. Doug Graham, a raw food pioneer and creator of the 80/10/10 diet, to explore how a plant-based, low-fat, high-carbohydrate diet can transform brain health. 

We discuss real-life cases of patients whose Alzheimer’s symptoms improved dramatically and how personalized nutrition plays a critical role in maintaining mental clarity, insulin sensitivity, and overall health.

You’ll discover why fruits and vegetables aren’t just “health foods,” how dietary volume, fiber, and simple sugars fuel your brain, and the science behind customizing your diet for maximum cognitive performance. 

This episode is packed with actionable insights you can start applying today. Tune in and learn how to harness the power of plants for your brain health!

This episode is sponsored by Organifi

- Get 20% off organic superfood blends at www.organifi.com/DRJOSH with code DRJOSH

“Healthier athletes always outperform the equally talented but less healthy athletes…Access to greatness is outside of the comfort zone.” 

~ Dr. Doug Graham

In this Episode

02:55 - Reversing Alzheimer’s cases

15:25 - Freedom to choose your food

17:45 - Personalizing patient diets

33:16 - Transitioning patients successfully

40:50 - Understanding 80/10/10 macros

49:33 - Meal frequency and calories

59:53 - Fasting vs. satisfying eating

1:07:48 - Unlocking human potential

1:12:01 - Working with Dr. Graham

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

Connect with Dr. Doug Graham: 

- Website - https://foodnsport.com/

- YouTube - https://www.youtube.com/@FoodnSport

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

We all know we should eat more greens, but did you know that the plants you grow and how you prepare them can be your secret weapon for boosting brain health?

Today, I interview John Kohler, a pioneer in raw food, home gardening, and plant-based nutrition, to explore how growing and eating nutrient-dense plants can protect your brain and even help prevent Alzheimer’s. 

John shares his journey of overcoming viral spinal meningitis in his 20s and turning adversity into a lifelong mission of health, wellness, and educating millions through his videos and podcasts. He takes us deep into the garden, sharing how growing your own greens from sprouts to microgreens can deliver far more nutrients than store-bought produce, and walks through his methods for maximizing plant nutrition. 

Whether you have a backyard or just a windowsill, John explains actionable steps to make plants a daily brain-boosting habit. If you’re ready to take control of your brain health and learn how to harness the benefits of plants for cognitive vitality, this episode is packed with insights you can start applying today.

This episode is sponsored by Organifi

- Get 20% off organic superfood blends at www.organifi.com/DRJOSH with code DRJOSH

“When you make a lot of money, that's great because it shows you're really skilled at making money. But that says nothing about how good you are at taking care of your health, which I believe is more important.” 

~ John Kohler

In this Episode

03:04 - John's early life events, lifestyle, and Alzheimer’s risk

13:59 - The impact of lifestyle changes in Alzheimer’s patients

16:39 - Growing your greens wherever you are

22:11 - Sprouts and microgreens: young plants pack the most nutrients

26:59 - Top brain-boosting plants

31:45 - Chewing greens to boost nitric oxide and brain function

34:45 - The impact of juicing and blending on plants

39:25 - Gardening for exercise, stress relief, and nature connection

42:15 - How to prevent plant pests without using pesticides

45:00 - John's daily meal preparation

56:36 - Stressing your plants so they produce more antioxidants

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

- Ornish study shows lifestyle changes improved cognition in early Alzheimer’s patients - https://lifestylemedicine.org/ornish-research/

Connect with John Kohler: 

- YouTube - https://www.youtube.com/@growingyourgreens

- Instagram - https://www.instagram.com/growingyourgreens/

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

We all know we need water to survive, but what if the very water we drink every day is silently contributing to brain diseases like Alzheimer’s? 

Toxins lurking in our tap water are often overlooked, but research shows that pollutants like PFAs, heavy metals, and fluoride can, in fact, affect our brain health.

In this enlightening episode, I interview Dr. Roy Speiser, a leading expert in water quality and environmental toxins. We discuss the crucial role water plays in our brain health, and Dr. Speiser shares powerful insights on how to protect ourselves and our families from harmful exposure. 

Get ready to learn practical steps to purify your water and safeguard your brain health. Don’t miss this episode–it's a must-listen for anyone concerned about long-term cognitive function!

To work with Dr. Roy Speiser, visit https://cwrenviro.com or call 1-800-444-3563 and use the code DRJOSH to get a discount.

“Water is a crucial and very important source of life for your physiological functions. However, it's toxic...” 

~ Dr. Roy Speiser

In this Episode

04:29 - Toxins in tap water and their link to brain health

13:42 - PFAs and how they impact the immune system

23:45 - Water purification solutions for home use

25:11 - The growing contamination of water sources

35:42 - Steps for reducing water toxins in daily life

50:13 - Water quality insight from Dr. Speiser

56:06 - The future of water purification technology

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

- CWR News - https://cwrenviro.com/blog/

Connect with Dr. Roy Speiser: 

- Website - https://cwrenviro.com/

- Phone - 1-800-444-3563 (Use the code DRJOSH to get a discount)

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

Are you worried about Alzheimer’s affecting you or a loved one? Discover how detoxification and infrared therapy could be the game-changer for brain health and prevention.

In this episode, I interview Robby Besner, CEO of Therasage, to explore how detoxification and natural healing methods can enhance brain health. He shares his personal journey, which began when his daughter contracted chronic Lyme disease, and how it led him to develop technology for detoxification and improved health.

Robby explains the importance of detox pathways, the role of sunlight frequencies in healing, and the power of infrared saunas for mobilizing toxins. He also discusses the rising challenge of neurodegenerative diseases, especially Alzheimer's, and how chronic infections like Lyme disease can trigger or worsen such conditions. 

Tune in to discover how to apply these insights to enhance your health and brain function, beginning with simple yet effective tools.

This episode is sponsored by Organifi

- Get 20% off organic superfood blends at www.organifi.com/DRJOSH with code DRJOSH

“It doesn't have to be expensive to create that healing platform… Creating a safe home where you can control your air, water, and food, and then bringing sunlight into the equation, is a really great place to start. It's simple and inexpensive.” 

~ Robby Besner

In this Episode

07:05 - The role of toxicity and inflammation in neurological diseases 

11:53 - How detoxification impacts brain health and inflammation reduction

16:47 - The importance of a personalized approach to detoxification 

29:21 - Effects of EMF and the need for harmonizing technology

34:56 - Full-spectrum infrared therapy: mobilizing deep toxins for healing

49:56 - Promoting neuroplasticity to improve brain health and help in Alzheimer’s prevention

56:51 - Results of Robby’s longevity and vitality studies 

1:01:03 - Top 3 takeaways from today’s episode

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

Connect with Robby Besner: 

- Website - https://therasage.com/

- Instagram - https://www.instagram.com/therasageinfrared/

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

What if the key to reversing Alzheimer’s lies not just in the brain, but in the connection between your gut, immune system, and neurological health?

In this episode, Dr. Peter Kan, a triple-board certified specialist in Integrative Medicine, Functional Medicine, and Chiropractic Neurology, joins me to discuss a crucial approach to treating brain health through the brain-immune-gut connection. Instead of just diagnosing and treating symptoms, Dr. Kan focuses on finding the root causes of neurological disorders, particularly Alzheimer’s and dementia, to implement proactive, personalized treatments.

Dr. Kan shares how the right approach, through diet, lifestyle, and gut health, can slow or even reverse neurological decline. He also emphasizes the importance of early detection and the use of neuro-metabolic integration in treating cognitive disorders. His holistic philosophy encourages patients to take control of their brain health before it’s too late. Listen in for actionable insights that could change how you approach Alzheimer’s prevention.

“I don't need to know your diagnosis to help you. I just need to know what you are presenting with, and what's driving those symptoms on a neurological or cellular level. And then we can start to do something to see if we can make a change.” 

~ Dr. Peter Kan

In this Episode

01:39 - Limitations of traditional neurology vs. functional neurology

09:05 - Dr. Kan's process for helping dementia patients

16:18 - The brain-immune-gut connection and why it's critical for brain health

22:27 - Personalized care and streamlining the course of treatment

23:58 - Importance of neurotransmitter balance for brain function

28:17 - The connection between blood sugar and brain health

32:34 - Impact of nutrition and exercise on the brain

40:19 - Neuroplasticity: the brain’s ability to heal with the right tools

42:09 - Exploring vagus nerve stimulation for treating chronic conditions

44:13 - Top three takeaways from the episode

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

Connect with Dr. Peter Kan: 

- Website - https://askdrkan.com/

- YouTube - https://www.youtube.com/@DrPeterKan

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

Could spike protein be the hidden culprit behind brain fog, cognitive decline, and even Alzheimer's disease? Dr. Mobeen Syed (also called Dr. Mobeen or DrBeen) joins me to discuss the concerning persistence of the spike protein in the body and its potential to accelerate the progression of neurodegenerative conditions.

In this thought-provoking conversation, you'll learn about the latest studies revealing the impact of the spike protein on brain health and Alzheimer's disease. Dr. Mobeen discusses how it lingers in the body long after infection or vaccination, potentially causing long-term damage. We’ll explore the mechanisms by which the spike protein enters the brain, disrupts the blood-brain barrier, and leads to inflammation and cognitive decline.

If you’re concerned about Alzheimer's or want to understand how to protect your brain, don't miss this episode. Get informed, and join us in the fight against cognitive decline.

This episode is sponsored by Organifi

- Get 20% off organic superfood blends at www.organifi.com/DRJOSH with code DRJOSH

“Controlling inflammation does not fix the problem, but it fixes or reduces the damage done because of the problem.” 

~ Dr. Mobeen Syed, MD, MSc

In this Episode

03:21 - Can spike protein persist in the brain for months or even years?

22:51 - How the spike protein damages the brain

46:45 - Spike protein and its role in endothelial cell dysfunction

53:36 - Vaccine-derived vs. infection-derived spike protein

1:06:49 - Managing spike protein damage: Is recovery possible?

1:19:19 - Interventional studies on TLR antagonists

Links to the Articles: 

-Spike Protein Fragments Promote Alzheimer’s Amyloidogenesis | ACS Applied Materials & Interfaces - https://pubs.acs.org/doi/10.1021/acsami.3c09815

-SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein | Molecular Psychiatry - https://www.nature.com/articles/s41380-022-01831-0?utm_source=chatgpt.com

-Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination | medRxiv - https://www.medrxiv.org/content/10.1101/2025.02.18.25322379v2

-Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination - https://www.medrxiv.org/content/10.1101/2025.02.18.25322379v2.full.pdf

-Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19: Cell Host & Microbe - https://www.cell.com/cell-host-microbe/fulltext/S1931-3128%2824%2900438-4?utm_source=chatgpt.com

-Unraveling the SARS-CoV-2 spike protein long-term effect on neuro-PASC - PMC - https://pmc.ncbi.nlm.nih.gov/articles/PMC11688492/?utm_source=chatgpt.com

-Full article: Detection of S1 spike protein in CD16+ monocytes up to 245 days in SARS-CoV-2-negative post-COVID-19 vaccine syndrome (PCVS) individuals - https://www.tandfonline.com/doi/full/10.1080/21645515.2025.2494934#d1e1497

-The spike protein of SARS-CoV-2 induces endothelial inflammation through integrin α5β1 and NF-κB signaling - PMC - https://pmc.ncbi.nlm.nih.gov/articles/PMC8820157/?utm_source=chatgpt.com

-Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment | Nature Neuroscience - https://www.nature.com/articles/s41593-024-01576-9?utm_source=chatgpt.com

-SARS-CoV-2 and the spike protein in endotheliopathy: Trends in Microbiology - https://www.cell.com/trends/microbiology/fulltext/S0966-842X%2823%2900189-0?utm_source=chatgpt.com

-Duration of SARS-CoV-2 mRNA vaccine persistence and factors associated with cardiac involvement in recently vaccinated patients | npj Vaccines - https://www.nature.com/articles/s41541-023-00742-7?utm_source=chatgpt.com

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

- Courses from Dr. Mobeen Syed - https://members.drbeen.com/courses

Connect with Dr. Mobeen Syed: 

- Website - https://www.drbeen.com/

- YouTube - https://www.youtube.com/@DrBeenMedicalLectures

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

Are you ready for a new perspective on aging and brain health? In this episode, I had the privilege of interviewing Ted Teele, the visionary behind longevity communities. We discuss the future of senior living, examining how his groundbreaking approach combines science, technology, and wellness to create environments that foster healthier, happier aging.

Ted shares insights on how AI, personalized health data, and community support are transforming cognitive health, especially in the fight against Alzheimer’s. From his journey with heart health to the innovation of longevity communities, this episode is packed with actionable advice for anyone seeking to enhance their brain function and live a longer life.

Don’t miss this conversation on building a better future for senior living!

“I do think, within any community environment, there will be some people…that will move into the community because it is not the place you go to die. It is the place you go to enhance your cognitive skills and your overall health.” 

~ Ted Teele

In this Episode

08:13 - Longevity communities: a new model for senior living

10:46 - The four P’s of scientific wellness and its impact on aging

15:40 - Cognitive wellness programs to slow dementia

24:53 - Introducing scientific wellness in senior living communities

27:43 - Overcoming resistance in traditional senior living

32:01 - Longevity day programs: boosting cognitive health at home

43:24 - How to get involved with longevity communities

47:40 - Ted’s recommended relaxation exercises

49:44 - The future of longevity communities in senior living

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

- The Age of Scientific Wellness by Leroy Hood & Nathan Price - https://www.hup.harvard.edu/books/9780674245945

- BrainHQ - https://www.brainhq.com/

Connect with Ted Teele:  

- LinkedIn - https://www.linkedin.com/in/ted-teele-26b3421/

- Longevity Community -https://www.linkedin.com/company/longevitycommunityconsultants

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.

What if skipping a meal could help save your brain? In this episode, Dr. Mark Mattson and I discuss the fascinating world of intermittent fasting. We explore cutting-edge science and groundbreaking research that shows how intermittent fasting can not only prevent Alzheimer’s but may also reverse its effects.

Dr. Mattson, a neuroscientist and a leading expert in brain health, shares his insights on how lifestyle changes, especially fasting, influence brain health by enhancing neuroplasticity, improving memory, and protecting against neurodegenerative diseases. 

Whether you're looking to boost brain function or protect your cognitive future, this episode is a must-listen. Tune in to discover the potential of fasting to transform brain health, backed by decades of research. This enlightening conversation could change the way you think about food and its impact on your brain!

This episode is sponsored by Organifi

- Get 20% off organic superfood blends at www.organifi.com/DRJOSH with code DRJOSH

“The reason that exercise and intermittent fasting or short-term fasts are so safe is because they're so evolutionarily common in the history of evolution of animals and our human ancestors.” 

~ Dr. Mark Mattson

In this Episode

08:37 - Glutamate, fasting, and exercise connection

21:07 - The cyclic metabolic switching theory of intermittent fasting

39:07 - The role of the enzyme Glutamate Decarboxylase (GAD) 

42:02 - How to get your ketone levels up

51:27 - How long is fasting supposed to last?

1:02:18 - The future of Alzheimer's treatment

Resources:

- Top Supplements for Alzheimer's Guide - https://bit.ly/drjoshguide

- Adaptive Stress Response (PDF) - https://drive.google.com/drive/folders/1TKOygHIyD4zrgE-uvEvfeBQN09qZ15tV?usp=sharing

- Book: The Intermittent Fasting Revolution by Dr. Mark Mattson - https://www.amazon.com/dp/0262046407

- The Cyclic Metabolic Switching Theory of Intermittent Fasting by Dr. Mark Mattson - https://www.nature.com/articles/s42255-025-01254-5

- What Doesn't Kill You Dr. Mark Mattson - https://pubmed.ncbi.nlm.nih.gov/26204714/

- Potential Benefits and Harms of Intermittent Energy Restriction and Intermittent Fasting Amongst Obese, Overweight and Normal Weight Subjects by Dr. Michelle Harvie - https://www.mdpi.com/2076-328X/7/1/4

Connect with Dr. Mark Mattson:  

- Website - https://neuroscience.jhu.edu/research/faculty/57

- Email - [email protected]

- YouTube (Podcast)  - https://www.youtube.com/channel/UCgWFU7DT5meHnrDbtlL4Yxw

Connect with Dr. Josh Helman, MD:

- Instagram - https://www.instagram.com/greenbrainsMD

- Facebook - https://www.facebook.com/greenbrainsmd/

- LinkedIn - https://www.linkedin.com/in/doctorjosh

- TikTok - https://www.tiktok.com/@greenbrainsmd

- YouTube - https://www.youtube.com/channel/UCUMtFP2icmNEhOaSsd-CrSg?sub_confirmation=1

- Others - https://linktr.ee/greenbrainsmd

Disclaimer: Please remember that this podcast is for informational purposes only and is not intended as medical advice. Always consult your doctor or healthcare professional before making any changes to your treatment plan.