November 24, 2025

Antidepressants (SSRI) Trigger Hyponatremia, Which Causes Severe Anxiety

8 minutes

Antidepressants like SSRIs are strongly linked to hyponatremia, a dangerous drop in blood sodium that disrupts nerve and muscle function
The risk is highest in the first two weeks of treatment, when sodium levels plummet to life-threatening lows that trigger confusion, seizures, or fainting
Older adults, especially women over 80, are among the most vulnerable, with nearly 1 in 15 experiencing profound sodium loss after starting these drugs
Symptoms of drug-induced low sodium often mimic worsening anxiety or depression, leading to misdiagnosis and unnecessary increases in medication
Natural strategies like optimizing nutrition, restoring key vitamins and minerals, daily movement, sunlight exposure, and restful sleep offer safer ways to support mood and energy without creating sodium imbalances

...more

By Dr. Mercola

4.6

14871,487 ratings

November 24, 2025

8 minutes

Antidepressants like SSRIs are strongly linked to hyponatremia, a dangerous drop in blood sodium that disrupts nerve and muscle function
The risk is highest in the first two weeks of treatment, when sodium levels plummet to life-threatening lows that trigger confusion, seizures, or fainting
Older adults, especially women over 80, are among the most vulnerable, with nearly 1 in 15 experiencing profound sodium loss after starting these drugs
Symptoms of drug-induced low sodium often mimic worsening anxiety or depression, leading to misdiagnosis and unnecessary increases in medication
Natural strategies like optimizing nutrition, restoring key vitamins and minerals, daily movement, sunlight exposure, and restful sleep offer safer ways to support mood and energy without creating sodium imbalances

...more