To Health With That! MTHFR Mutations and Methylation.

Are Overmethylator and Undermethylator Still Useful Terms?


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I have used the terms over methylator and undermethylation in the past to help categorize people to streamline their supplement start with MTHFR or other methylation imbalance, but the terms themselves can be confusing and misleading because they imply a biochemical state that isn't actually there.

Logically, it makes sense that an undermethylator would be globally undermethylating things, but that doesn't bear out in reality, and part of that is because these terms (over- and under-methylator) were coined well before we had as much knowledge about the actual biochemistry and genetics linked to it as we do now.
Categorizing people in this way does still have some uesful aspects because many of the traits we see in people with methylation imbalance that are used to determine over and under-methylators, still point to some predictable medication reactions, supplement guidelines and other useful information.
So how do we keep the good without keeping the names? Tune in next episode because we'll be talking about a new way of looking at this. Methylation Archetypes.
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To Health With That! MTHFR Mutations and Methylation.By Dr. Amy Neuzil

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