The To Health With That! Podcast for MTHFR folks has been a wild ride, but so far it's really just Dr. Amy talking about MTHFR.In Season Five, which will start airing in September, I want YOU to talk. Tell me about your experience of being a person with MTHFR gene mutations, tell me what has helped you, what hasn't been helpful, and what you want all the other MTHFR folks out there to know.Your journey probably has other conditions intersecting as well. Maybe it's diabetes, migraines, thyroid conditions, infertility, or breast implant illness. Maybe it's chronic fatigue, mold illness, or something totally different. I want to hear about all of it. If you're an MTHFR mutant, I'd love to hear from you.Share your story on the podcast! Schedule your interview at tohealthwiththat.com or email me with questions. [email protected], go straight to the calendar link here: https://calendly.com/amy-tohealthwiththat/new-meetingThanks so much for watching! I have so many other resources for you. Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ GENETIC ROCKSTARS (an MTHFR, methylation, and genetics community): community.tohealthwiththat.comAFFILIATE LINKS: Thanks so much for using these links to buy the products you would buy anyway. This allows me to keep putting information out there at no cost to you. You’re the best!SEEKING HEALTH (methylation and histamine support supplements - ships internationally): https://bit.ly/3afXYH4STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwtQUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more

In the last episode, we talked about CBD as a methylation adaptogen, but we haven' talked too much about that term so let's dive in. We know that everyday methylation is important for people with the MTHFR gene or with any methylation dysfunction, but it turns out that long-term methylation care is important too and this can be achieved by getting methylation adaptogens.Methylation adaptogens are substances that help to regulate the amount your genes are methylated. Remember that when genes are methyalted, they are turned off and when they are unmethylated they are turned on. So having stretches of your genome that are undermethylated means the genes in there are allowed to function out of control, and that could lead to bigger problems like cancer.Methylating your genes appropriately is one of the long-term ways to prevent disease and even benefit your children, because research has shown that the way you methylate your genes might pass to your children. Not just the genes themselves, but the methylation tags.The most researched compounds that have been called methylation adaptogens come from food sources - things like caffeic acid from coffee and cruciferous veggies, lycopene from tomatoes and watermelon, resveratrol from red wine. Thanks so much for watching! I have so many other resources for you. Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ GENETIC ROCKSTARS (an MTHFR, methylation, and genetics community): community.tohealthwiththat.comAFFILIATE LINKS: Thanks so much for using these links to buy the products you would buy anyway. This allows me to keep putting information out there at no cost to you. You’re the best!SEEKING HEALTH (methylation and histamine support supplements - ships internationally): https://bit.ly/3afXYH4STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwtQUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more

Pot is the third most used drug in North America after alcohol and tobacco, so questions about Cannabis and MTHFR are important to ask. The answers, of course, are mixed with some serious pitfalls and also some surprising benefits of CBD for people with MTHFR gene mutations.Nothing is ever fully good or fully bad, and marijuana for MTHFR is the same. When you have an MTHFR gene variant, it is important to know your own risks to make an educated decision about what you want to put in your body. Medical marijuana is widely available and can come in various strengths of THC and CBD, which will affect people with the MTHFR gene mutation in different ways.With MTHFR we do have a different risk profile than average, so educate yourself, advocate for yourself, and be careful about what you put in your body.Thanks so much for watching! I have so many other resources for you. Check out the website first for lots of FREE stuff:WEBSITE: https://tohealthwiththat.com/ GENETIC ROCKSTARS (an MTHFR, methylation, and genetics community): community.tohealthwiththat.comAFFILIATE LINKS: Thanks so much for using these links to buy the products you would buy anyway. This allows me to keep putting information out there at no cost to you. You’re the best!SEEKING HEALTH (methylation and histamine support supplements - ships internationally): https://bit.ly/3afXYH4STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwtQUEEN OF THE THRONE (castor oil and castor oil packs):  https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more

Methylation imbalance and the causative factors leading to methylation imbalance, like the MTHFR gene mutation, show themselves in four distinct personality types. These methylation personality types, methylation archetypes, or MTHFR personalities are called The Achiever, The Athlete, The Activist, and The Artist.The Activist and The Artist are very closely linked. Neither are terribly ambitious or driven, except in the thing that matters to them, whether it's their art, their job (which might not be art or activism), or the cause that matters to them. Both tend to have fewer allergic-type reactions but are more likely to have food sensitivities or chemical sensitivities. Things like wheat sensitivity, soy sensitivity, rashes with the wrong laundry detergent, or headaches after smelling perfume. Both of these personalities thrive on leftovers and fermented foods, even though leftovers and fermented foods are high in histamine.These two personality types also tend to react predictably to supplements, nutrients, and even pharmaceutical drugs. Anything that boosts serotonin, so SSRI medications, St. John's Wort, and melatonin aren't great for these groups. Likewise, the major methyl donors like SAMe, TMG, and DMG are typically not well tolerated by the artist and the activist. Conversely, these groups usually do very well with good sources of folate, like L-5MTHF, food-sourced folate, or folinic acid. Like all people with methylation imbalance, folic acid should not be taken because it can make methylation imbalances worse. Also, the benzodiazepine class of pharmaceuticals is usually well tolerated (although your doctor knows the best choice of pharmaceuticals for you, and your doctor's information is always more informed and correct for you than ours.)Thanks so much for watching today! If you haven't yet discovered your methylation archetype or methylation personality, take the quiz for free now at tohealthwiththat.comAlso, if you're a crappy methylator, MTHFR mutant, or have chronic health issues and you can't figure out why, then check out our online health community. Community.tohealthwiththat.comIf you wish to support this channel by using affiliate links when you buy supplements and self-care that you want to buy anyway, I would appreciate it!Seeking Health: https://bit.ly/3afXYH4Amazon: https://www.amazon.com/s?k=Health+best+sellers&i=stripbooks&camp=1789&creative=9325&linkCode=ur2&linkId=29fff6e3ea954499d2eed32d46428454&tag=tohealthwitht-20\Fullscript (for other supplements): https://us.fullscript.com/welcome/thwtQueen of The Thrones Castor Oil Packs: https://shop.queenofthethrones.com/amy-tohealthwiththatFor 10% off any order of $59 or more, use the code AMY_TOHEALTHWITHTHAT10

,Methylation imbalance and the causative factors leading to methylation imbalance, like the MTHFR gene mutation, shows itself in four distinct personality types. These methylation personality types, methylation archetypes or MTHFR personalities are called The Achiever, The Athlete, The Activist, and The Artist.The Achiever and The Athlete are very closely linked. Both are extremely ambitious, perfectionistic, competitive, and driven. Both tend to have more allergic-type reactions to the world. Things like hay fever, hives, dermatographia, and skin flushing with a workout. Neither of these personalities tend to tolerate leftovers very well (because leftovers are also high in histamine).These two personality types also tend to react predictably to supplements, nutrients, and even pharmaceutical drugs. Anything that boosts serotonin, so SSRI medications, St. John's Wort, and melatonin do well for these groups. Likewise, the major methyl donors tend to do well. These are SAMe, TMG, and DMG. Conversely, these groups don't do as well with folate, even the MTHFR-safe forms like L-5MTHF or folinic acid. Also, the benzodiazepine class of pharmaceuticals isn't usually the best choice (although your doctor knows the best choice of pharmaceuticals for you, and your doctor's information is always more informed and correct for you than ours.)Thanks so much for watching today! If you haven't yet discovered your methylation archetype or methylation personally, take the quiz now at tohealthwiththat.comAlso, if you're a crappy methylator, MTHFR mutant, or have chronic health issues and you can't figure out why, then check out our online health community. Community.tohealthwiththat.comPlease support this channel by using affiliate links when you buy supplements and self-care that you wanted to buy anyway (I really appreciate it!):Seeking Health: https://bit.ly/3afXYH4Amazon: HereFullscript (for other supplements): https://us.fullscript.com/welcome/thwtQueen of The Thrones Castor Oil Packs: https://shop.queenofthethrones.com/amy-tohealthwiththatFor 10% off any order of $59 or more, use the code AMY_TOHEALTHWITHTHAT10

Methylation imbalance, often caused by the MTHFR gene mutation, by folic acid excess, or by nutritional deficiencies, shows itself in several personality traits.

use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more

I have used the terms over methylator and undermethylation in the past to help categorize people to streamline their supplement start with MTHFR or other methylation imbalance, but the terms themselves can be confusing and misleading because they imply a biochemical state that isn't actually there.

She breaks down the considerations for symptom management and potential risks, particularly regarding tumors and blood labs. In this episode of 'To Health With That,' naturopathic doctor Amy Neuzil discusses the complexities surrounding methylfolate dosing for individuals with MTHFR. High doses of methylfolate could come with some of the same risks as high-dose folic acid, so it's essential to find the right dose for you without overdoing it. The three factors to consider are symptom management, potential risks, and serum folate levels. She breaks down the considerations for symptom management, potential risks, particularly regarding tumors, and blood labs. Amy also shares her own methylfolate regime and emphasizes the importance of personalized care and listening to one’s body.

Folate is a great thing - it's vitamin B9 and your body needs it to make new cells, replicate DNA, and so much more. But there are risks of too much folate, so how much folic acid is too much? And how dangerous is it to take high dose folic acid over time? The research exists for high dose folic acid, but what about L-5MTHF, or methyl folate? Does high dose methyl folate have the same risks as high dose folic acid?

We have so many questions, and very few definitive answers, but there is lots of information that we do have.

Thanks for watching! Here are some other links that you might like.

Genetic Rockstars - a community for people making the most of their favorite genes and getting better together (first month free for YouTubers!): https://community.tohealthwiththat.com/plans/204575?bundle_token=4da8ed9c5f00a92363bcd15ad2ac26dd&utm_source=manual

FREE MTHFR Basics course: https://courses.tohealthwiththat.com/p/mthfr-basics

I would appreciate it so much if you would support this channel by using affiliate links when you buy supplements and resources (I heart you!):

Seeking Health:  https://bit.ly/3afXYH4

Amazon: https://www.amazon.com/s?k=Health+best+sellers&i=stripbooks&camp=1789&creative=9325&linkCode=ur2&linkId=29fff6e3ea954499d2eed32d46428454&tag=tohealthwitht-20

Queen of The Thrones Castor Oil Packs:  https://shop.queenofthethrones.com/amy-tohealthwiththat 

For 10% off any order of $59 or more, use the code AMY_TOHEALTHWITHTHAT10

That's right - season 4 of the To Health With That podcast is finished, so let's talk about what you should be doing this summer (having fun), what I should be doing in the fall (writing), and what kind of episodes you can expect.