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The complex science of dietary lipids (fats) and inflammation, with actionable advice for managing health through dietary choices.

Note: Full episodes are available to paid subscribers on the M&M Substack and are free on YouTube. Partial versions are available elsewhere.

About the guest: Tim Yeatman, MD is a surgical oncologist and professor of surgery at the University of South Florida, also serving as an Associate Center Director for Translational Research and Clinical Innovation at the Tampa General Cancer Institute. Ganesh Halade, PhD is an Associate Professor in the Department of Internal Medicine, focusing on cardiovascular diseases with research centered on inflammation and resolution signaling.

Episode summary: Explores the link between dietary lipids, particularly omega-6 fatty acids from seed oils, chronic inflammation, and cancer. It starts with a historical perspective on cancer as an inflammatory disease, referencing the work of Rudolf Virchow, and delves into how modern diets have shifted to include an imbalance of omega-6 to omega-3 fatty acids, leading to chronic inflammation. Includes insights from a recent study by Yeatman and Halade on lipid dysregulation in colon cancer, explaining how this imbalance can contribute to the development of cancer and other diseases. The conversation also touches on lifestyle factors like diet, exercise, and sleep, and how they interact with lipid metabolism to affect health outcomes.

Related episodes:

• M&M #136: Seed Oils, Omega-6 PUFAs, Inflammation, Obesity, Diabetes, Chronic Disease & Metabolic Dysfunction | Chris Knobbe 

*This content is never meant to serve as medical advice

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