In this episode of the Smarter Not Harder Podcast, our guest Dr. Andrew Gallimore joins our host Dr. Ted Achachoso to give 1 cent solutions to the following $64,000 questions:

• Does dimethyltryptamine make the brain construct a different reality or does it make the brain perceive a different reality based on the information that it was receiving?
• How do molecules such as LSD, DMT, psilocybin, and mescaline switch one's reality from one channel to another
• Why is the fly agaric psychedelic?

Dr. Andrew Gallimore is a British neurobiologist, chemist, pharmacologist and writer based in Tokyo, Japan. He has been interested in the relationship between psychedelic drugs, the brain, consciousness, and the structure of reality. He has written a couple of books that he illustrated and self-published. His works are Alien Information Theory: Psychedelic Drug Technologies, and the Cosmic Game (2019), and Reality Switch Technologies: Psychedelics as Tools for the Discovery and Exploration of New Worlds (2022). What we discuss:

[00:00] Dr. Andrew Gallimore discusses his self-published book on psychedelic drug technologies and the structure of reality

[09:12] DMT and Conway's Game of Life illustrate the emergence of complexity from simple rules

[25:29] DMT experience reveals highly intelligent, hyper-dimensional space beyond our reality

[34:06] DMT allows the brain to construct an alternate reality without affecting critical parts.

[49:36] Salvanorin inhibits the claustrum, which releases the cortex and creates novel emergent patterns of activity.

[57:19] Salvia tears apart the fabric of reality while classic psychedelics allow the brain to reach new states

[1:12:43] Different drugs affect perception and reality in different ways.

[1:20:42] Inhibitory interneurons control excitation inhibition balance

[1:36:11] Positive allosteric modulators can enhance receptor activity without the presence of an endogenous agonist.

[00:15] Muscimol and its Psychedelic Properties

Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Dr. Andrew Gallimore: Website: http://alieninsect.net/ Twitter: @alieninsect Instagram: @alieninsect YouTube: youtube.com/c/alieninsect Books:

• Alien Information Theory: Psychedelic Drug Technologies and the Cosmic Game

• Reality Switch Technologies: Psychedelics as Tools for the Discovery and Exploration of New Worlds

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