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Question: Eggs, Choline Bisulfate, and TMAO If you really want to know what eggs are doing to your TMAO, then I'm pretty sure Cleveland Clinic has a TMAO blood test, and that would be the best way to do it. Yeah, the Cleveland heart lab has a TMAO blood test, so you could test your response to this. If you didn't want to test, then if you assumed the worst case scenario, I would say you could probably just eat two eggs at a time and you would not raise your TMAO that much, but if you do test TMAO, you can probably show that you might be able to get away with eating six eggs at a time and not raise your TMAO that much.

But the thing is, I don't think you're going to get the same response from six eggs at a time as in that study, as you would get from eating two eggs separated and spread out from the day. And the reason is I think the TMAO is mostly generated from the choline that does not get absorbed in the small intestine, going to the colon, being available to the microbiome. So if you lower the dose of eggs and spread them out, then you should be able to kind of totally head off significant TMAO generation.

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DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

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Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome