Épigénétique et mémoire cellulaire - Edith Heard

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

Conférence - Harold E. Varmus : How Can Science and Its Benefits Be Shared Globally? How Medical Science Can Be Used in Developing Countries

Harold E. Varmus

Prix Nobel de physiologie ou médecine

Résumé

In the final lecture, I will talk about the ways in which parts of the scientific enterprise are trying to create a world in which the opportunities to be a scientist and to share the benefits of science are available everywhere. I will talk about several initiatives, supported by governments or philanthropies, that either promote science as a global activity or improve access to advances in health care made possible by science. The initiatives will include examples funded by the US government, French-American collaborations, the World Health Organization, and others, to reduce the toll taken by malaria, cancers, and other diseases.

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

Conférence - Harold E. Varmus : How Can Science and Its Benefits Be Shared Globally? How Medical Science Can Be Used in Developing Countries

Harold E. Varmus

Prix Nobel de physiologie ou médecine

Résumé

In the final lecture, I will talk about the ways in which parts of the scientific enterprise are trying to create a world in which the opportunities to be a scientist and to share the benefits of science are available everywhere. I will talk about several initiatives, supported by governments or philanthropies, that either promote science as a global activity or improve access to advances in health care made possible by science. The initiatives will include examples funded by the US government, French-American collaborations, the World Health Organization, and others, to reduce the toll taken by malaria, cancers, and other diseases.

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

04 - L'épigénétique à l'interface organisme-environnement : Exemples d'impacts environnementaux sur le règne végétal

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

04 - L'épigénétique à l'interface organisme-environnement : Exemples d'impacts environnementaux sur le règne végétal

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

Conférence - Harold E. Varmus : How Do Scientists Inform Others about Their Work? Why Evolving Publication Practices Are Contentious

Harold E. Varmus

Prix Nobel de physiologie ou médecine

Résumé

I will talk about how scientists inform others about their results, with emphasis on the rise of scientific journals and the often excessive importance conferred upon work that appears in a few especially prestigious venues. A central element of this lecture will concern the use of the internet to make scientific information more accessible through public digital libraries, "open access" publication practices, preprint servers, and posts in social media. Problems associated with publication practices and peer review – including non-reproducibility, misconduct, and misuse of artificial intelligence – will also be discussed.

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

03 - L'épigénétique à l'interface organisme-environnement : Exemples d'impacts environnementaux sur le règne animal

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

Conférence - Harold E. Varmus : How Do Scientific Discoveries Affect the Way We Live? How Studies of a Chicken Virus Changed Cancer Therapy

Harold E. Varmus

Prix Nobel de physiologie ou médecine

Résumé

The main theme of the second lecture concerns the way in which fundamental biological research (as an example, my own work to identify and characterize the genes that produce cancers in animals) can produce important benefits for society (e.g., by leading to better treatments of common lethal human diseases, like cancer). I will also comment on the societal elements (commercial, regulatory, etc) required to change medical practice after scientific discoveries are made.

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

02 - L'épigénétique à l'interface organisme-environnement : Comment l'environnement influence-t-il les phénotypes ?

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

Conférence : Reflections on the Scientific Enterprise

Who Becomes a Professional Scientist and Why? My Path from Literature and Medicine to Basic Biology

Harold E. Varmus

Prix Nobel de physiologie ou médecine

Résumé

I will begin by talking about the nature of scientific thought, contrasted with the experience of working in a complex "enterprise." Then I will note some of the reasons (personal, cultural, economic, political or other) that explain why people chose a career in science. I will describe in detail my own unusual route, influenced by literature, medicine, the Vietnam War, and finally the appeal of laboratory work. I will also recount how choice of a scientific career was displayed in a famous old movie and summarize my concerns about the unequal representation in the demography of science.

Edith Heard

Collège de France

Epigénétique et mémoire cellulaire

Cours 2023-2024

01 - L'épigénétique à l'interface organisme-environnement : Introduction