Welcome to the metabolism masterclass!

Dr. Ben Bikman (Ph.D Professor BYU), a powerhouse in metabolism science, joins Dave to expose the truth about insulin resistance—the silent epidemic fueling obesity, chronic disease, and low energy. Forget the outdated calorie-counting nonsense (it doesn’t work)—Dr. Bikman reveals how your hormones, not just your diet, control your metabolism and what you can do to reset it fast. 

From debunking diet myths to uncovering why some people can eat 400 grams of carbs and never gain fat (hint: it’s not what you think), this episode unpacks the real science of fat storage, energy, and optimal health. Get ready for mind-blowing insights, metabolic hacks, and a new way to think about food, fasting, and longevity. 

What You’ll Learn: 

• The #1 driver of insulin resistance—and why most doctors miss it 

• Why eating more fat (yes, really) could be the key to reversing metabolic dysfunction 

• How fasting, cold therapy, and red light impact your metabolism 

• The truth about carbs, seed oils, and why some people can’t gain fat 

• How to tell if insulin resistance is wrecking your energy & health 

 Resources:  

• Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ 

•  Benjamin’s new book How Not To Get Sick :  https://a.co/d/aADlMWv 

• Benjamin’s YouTube Page –  https://www.youtube.com/@benbikman 

• 2025 Biohacking Conference: https://biohackingconference.com/2025 

• Danger Coffee: https://dangercoffee.com 

• Dave Asprey’s Website: https://daveasprey.com 

• Dave Asprey’s Linktree: https://linktr.ee/daveasprey 

• Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com 

• Own an Upgrade Labs: https://ownanupgradelabs.com 

• Upgrade Labs: https://upgradelabs.com 

• 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com 

SPONSORS:  

-Lumiram | Go to http://healthlighting.com/dave to save 10% on your order. 

-Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. 

Timestamps: 

00:00 Trailer 

00:52 Introduction to Dr. Benjamin Bikman 

02:20 The Battle Against Conventional Dietetics 

04:12 Understanding Insulin Resistance 

06:29 The Two Paths to Insulin Resistance 

10:19 Fasting and Metabolic Health 

14:11 Insulin and Cognitive Enhancement 

18:16 Identifying Insulin Resistance 

30:12 The Role of Insulin in Fat Storage 

42:04 Understanding Glucose and Insulin Dynamics 

42:26 The Role of Exercise in Glucose Regulation 

42:54 AMPK and Muscle Contraction 

45:21 Calories In, Calories Out Debate 

46:15 The Myth of Calorie Counting 

50:13 Ketosis and Metabolic Rate 

51:14 Intermittent Fasting and Muscle Preservation 

55:21 Insulin Resistance and Ketogenic Diets 

01:02:04 Circadian Rhythm and Insulin Sensitivity 

01:08:08 Environmental Toxins and Insulin Resistance 

01:13:03 The Impact of Seed Oils on Insulin Resistance 

01:19:22 Final Thoughts and Resources 

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