The Human Upgrade: Biohacking for Longevity & Performance

How to Build Strength Faster – John Jaquish, Ph.D., with Dave Asprey, Part 2 : 863


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In Part 1 of our two-part episode with John Jaquish, Ph.D., I talked with him about building bone density—an important factor in your strength and longevity. Don’t miss! Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D., with Dave Asprey, Part 1 – #862.

This inventor, author, and scientist created OsteoStrong and the X3 System, a series of devices that combine rehabilitation and advancements in human physiology to build bone density. His extensive research into bone density and strength found that you can approach weight lifting much differently than you may think.

“It appears that the most biological adaptation comes from not the area under the curve, the total volume of work you did, but has to do with how quickly did you go from zero to 100 and back to zero,” John says. “So, a very brief spike of almost anything causes way more adaptation than spiking up to 70% and holding it.”

Now in Part 2, our conversation dives into John’s other findings and lifestyle choices, both as a public figure, a mentor for professional athletes and a fasting enthusiast. We go off the beaten path on a few things:

  • Anabolic rebound after fasting (what fasting does to build muscle mass)
  • Tendon mutations (and how they make people outrageously strong)
  • Taking Viagra (or other non-pharmaceuticals) and carbs to trigger a muscle cell splitting
  • The difference between fructose, glucose and sucrose (is there any real difference in the body?)


We also talk about ways to eat for strength and the quest for longevity that guides him. He knows about the tempting danger of eating to only look good (but you feel like crap). He offers tips to make sure you don’t go there.

Check out John’s book to learn more: Weight Lifting Is a Waste of Time: So Is Cardio, and There’s a Better Way to Have the Body You Want

Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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The Human Upgrade: Biohacking for Longevity & PerformanceBy Dave Asprey

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