The Human Upgrade: Biohacking for Longevity & Performance

How Urolithin A Helps Create Super T-Cells & Boosts Immunity – Dr. Anurag Singh : 999


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Timeline Nutrition sponsored this podcast.

IN THIS EPISODE OF THE HUMAN UPGRADE™… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria. 

Urolithin A activates mitophagy and renews your mitochondria.  “It takes all the cellular garbage that has been accumulating over the aging process,” Dr. Singh explains. “It revs it up, so it recharges. And so now, you're cleaning your metabolic waste products much more efficiently and they become the building blocks. This is mitochondrial biogenesis, and that means newer, healthy mitochondria coming in.”

This new conversation takes an exciting turn into immunity and your immune system’s two lines of defense: innate and adaptive. You’ll learn:

  • how inflammation plus aging (AKA inflammaging) contributes to a weakened immune system and a growing incidence of cancer as you age;
  • how inflammaging and cancer are connected to mitochondrial dysfunction specifically during the aging process; and
  • how to approach your immune health differently with this new knowledge.


new study recently published in Immunity looks at how immune cells fight cancer better with a focus on immune modulation, immune cell exhaustion and immune responses. “A lot of urolithin A is anti-inflammatory, but a lot of it is immune modulation," Dr. Singh says. "So, it takes a rewiring of the immune system and makes it more conducive to stopping harmful immune responses.”

Watch this episode on YouTube!

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: To learn more about the benefits of urolithin A, go to https://www.timelinenutrition.com and use code UPGRADE10 to get 10% off the plan of your choice. 

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! 

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Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount

Isometrics for Cardiovascular Healthhttps://www.zona.com, use code DAVE2022 to get $150 off the Zona Plus. 

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The Human Upgrade: Biohacking for Longevity & PerformanceBy Dave Asprey

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