Infectious Disease Puscast

On episode #38 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 9/14 – 9/27/23.

Host: Daniel Griffin and Sara Dong

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• Features of Long COVID identified through immune profiling (Nature)
• Severity of influenza-associated hospitalizations by influenza type (The Lancet)
• Cefazolin for the treatment of CNS infections (CID)
• Rifampin based therapy for patients with Staphylococcus aureus native vertebral Osteomyelitis (CID)
• State of the management of infections caused by multidrug-resistant organisms (CID)
• Are contact precautions "essential" for the prevention of healthcare-associated methicillin-resistant Staphylococcus aureus? (CID)
• Impact of the sequential implementation of a pharmacy-driven methicillin-resistant Staphylococcus aureus (MRSA) nasal-swab ordering policy and vancomycin 72-hour restriction protocol on standardized antibiotic administration ratio (ICHE)
• Update on outbreak of fungal meningitis among US residents who received epidural anesthesia at two clinics in Mexico (CID)
• Paratracheal abscess by plant fungus Chondrostereum purpureum (MMCR)
• Canadian Blood Services traceback investigation of a suspected case of transfusion-transmitted malaria (Transfusion)
• Strongyloides infection screening in transplant candidates (TID)
• The world of microbial odors (JID)

Music is by Ronald Jenkees

On episode #37 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/31 – 9/13/23.

Click arrow to play Download Puscast 037 (22 MB .mp3, 31 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email

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• Association between varicella zoster virus and dementia (NS)
• Safety, efficacy, and immunogenicity of V160 vaccine in cytomegalovirus-seronegative women (The Lancet)
• Microorganisms detected in intussusception cases and controls in children (OFID)
• Clinician testing and treatment thresholds for management of UTIs (OFID)
• Clinical outcomes and management of NAAT-positive/toxin-negative Clostridioides difficile infection (CID)
• Associations of standard care, intrathecal antibiotics, and antibiotic impregnated catheters with cerebrospinal fluid shunt infection (JPIDS)
• Advances in asynchronous telemedicine call for increased antibiotic surveillance (CID)
• Two artificial tears outbreak-associated cases of extensively drug-resistant Pseudomonas aeruginosa detected through whole genome surveillance (JID)
• Pre-XDR congenital TB in an extremely premature baby (CID)
• Emerging Roles of (1→3)-β-D-glucan in cerebrospinal fluid for detection and therapeutic monitoring of fungal diseases (CID)
• Outbreak of locally acquired mosquito-transmitted malaria (CDC)
• Complexity of infectious diseases compared to other cognitive medical subspecialties (OFID)
• Risk of opportunistic infections associated with long-term glucocorticoid therapies in adults (CID)

Music is by Ronald Jenkees

On episode #36 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/17 – 8/30/23.

Host: Daniel Griffin

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• Detection of rotavirus in respiratory specimens from children aged under 2 years hospitalized for acute gastroenteritis (JID)
• Risk of Bell's palsy following SARS-CoV-2 infection (CMI)
• Evaluation and management of diabetes-related foot infections (CID)
• Impact of mandatory infectious disease specialist approval on Clostridioides difficile infection rates and testing appropriateness (CID)
• Role of cerebral imaging on diagnosis and management in patients with suspected infective endocarditis (CID)
• Identifying effective durations of antibiotic therapy for the treatment of carbapenem-resistant Enterobacterales bloodstream infections (CID)
• Impact on clinical outcome of follow-up blood cultures and risk factors for persistent bacteraemia (CMI)
• State-of-the-art review: Neurosyphilis (CID)
• Oritavancin compared to the standard of care for treatment of non-endovascular gram-positive bloodstream Infections (OFID)
• How to approach suppressive antibiotic therapy following debridement, antibiotics, and implant retention for prosthetic joint infection (CID)
• 2023 Duke-International Society for cardiovascular infectious diseases criteria for infective endocarditis (CID)
• Adjunctive diagnostic studies completed following detection of candidemia in children (JPIDS)
• Oral lipid nanocrystal amphotericin b for cryptococcal meningitis (CID)
• Efficacy of 23 commonly used liquid disinfectants against Candida auris (IC&HE)
• Burrow ink test for scabies (NEJM)
• Evolution of partial resistance to artemisinins in malaria parasites in Uganda (NEJM)
• Human neural larva migrans caused by Ophidascaris robertsi ascarid (EID)

Music is by Ronald Jenkees

On episode #35 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 8/3 – 8/16/23.

Host: Daniel Griffin

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• Powassan virus encephalitis: a tertiary center experience (CID)
• Diagnostic accuracy of hospital antibiograms in predicting the risk of antimicrobial resistance in Enterobacteriaceae isolates (CID)
• Timely diagnosis of incubating syphilis infections using Treponema pallidum (CID)
• Impact of rapid identification and stewardship intervention on coagulase-negative Staphylococcus bloodstream infection (OFID)
• Natural antibodies mediate protection against Acinetobacter baumannii respiratory infections (JID)
• Risk of misleading conclusions in observational studies of time-to-antibiotics and mortality in suspected sepsis (CID)
• Cryptococcal meningitis in young, immunocompetent patients (OFID)
• Experimental acquisition, maintenance, and transmission of methicillin-resistant Staphylococcus aureus (MRSA) (JID)
• Clinical characteristics and prognosis of pediatric Phthirus pubis coinfestation of the eyelashes and scalp hairs (AMJTMH)
• Prognostic significance of Lymphocyte Subpopulations for ICU-acquired Infections in sepsis patients (JHI)

Music is by Ronald Jenkees

On episode #34 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/20 – 8/2/23.

Host: Daniel Griffin

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• FDA approves first treatment for molluscum contagiosum (FDA)
• Identifying children likely to benefit from antibiotics for Acute Sinusitis (JAMA)
• Impact of metagenomic next-generation sequencing of plasma cell-free DNA testing in patients with suspected infectious diseases (OFID)
• Impact of infectious diseases consultation in patients with candidemia at a multisite healthcare system (OFID)
• Relapsing babesiosis with molecular evidence of resistance to certain antimicrobials commonly used to treat Babesia microti infections (OFID)
• Seroprevalence of Chagas disease among people of Latin American descent (AJTMH)
• Malaria transmission-blocking vaccines Pfs230D1-EPA and Pfs25-EPA in Alhydrogel in healthy Malian adults (The Lancet)
• The human blood fluke, Schistosoma mansoni, harbors bacteria throughout the parasite's life cycle (JID)
• Health care provider knowledge regarding Alpha-gal syndrome (CDC)

Music is by Ronald Jenkees

On episode #33 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/6 – 7/19/23.

Host: Daniel Griffin

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• Early antiretroviral therapy not associated with higher cryptococcal Meningitis mortality in people with HIV in high-income countries (CID)
• Implementing a rapid Antiretroviral therapy program using starter packs for emergency department patients diagnosed with HIV infection (OFID)
• Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk Penicillin allergy (JAMA)
• Infectious diseases consultation associated with reduced mortality in gram-negative bacteremia (CID)
• Positive impact of [18F]FDG-PET/CT on mortality in patients with Staphylococcus aureus Bacteremia explained by immortal time bias (CID)
• Azithromycin for bacterial watery diarrhea (JID)
• Periprosthetic joint infection: current clinical challenges (CID)
• Old World medieval Treponema pallidum complex treponematosis (JID)
• Clinical Impact of polymerase chain reaction–based Aspergillus and Azole resistance detection in invasive aspergillosis (CID)
• Superior accuracy of Aspergillus plasma cell-free DNA PCR over serum galactomannan for the diagnosis of invasive aspergillosis (CID)
• Tafenoquine co-administered with dihydroartemisinin–piperaquine for the radical cure of Plasmodium vivax malaria (The Lancet)
• Doubling of cyclosporiasis cases partially attributable to a salad kit (CDC)
• Efficacy and safety of adjunctive corticosteroids in the treatment of severe community-acquired pneumonia (BMC)

Music is by Ronald Jenkees

On episode #32 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/21 – 7/4/23.

Hosts: Daniel Griffin and Sara Dong

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• Clinical characteristics and outcomes among travelers with severe dengue (AIM)
• Phase 3 randomized trial of Bulevirtide in chronic hepatitis D (NEJM)
• Increased peripheral inflammation associated with structural brain changes and reduced blood flow in virologically controlled people with HIV (JID)
• Sustained viral suppression with dolutegravir monotherapy over 192 weeks in HIV patients (CID)
• Side-by-side comparative study of the immunogenicity of the intramuscular and intradermal rabies post-exposure prophylaxis regimens in suspected RABV exposed individuals (CID)
• Reliability of admission procalcitonin testing for capturing bacteremia across the sepsis spectrum (CCM)
• Early discontinuation of antibiotics in patients admitted with clinically suspected serious infection but negative cultures (OFID)
• Short-course therapy for urinary tract infections in children (JAMA)
• Autochthonous Leprosy in the United States (NEJM)
• Management of pediatric pneumonia (CID)
• Added value of (1,3)-β-D-glucan for the diagnosis of Invasive candidiasis in ICU patients (Infection)
• Selection for insecticide resistance can promote Plasmodium falciparum infection in Anopheles (PLOS Pathogens)
• Locally acquired malaria cases identified in the US (CDC)
• Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens (NN)

Music is by Ronald Jenkees

On episode #31 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/8 – 6/20/23.

Hosts: Daniel Griffin and Sara Dong

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• Relative effectiveness of the cell-based quadrivalent influenza vaccine in preventing cardiorespiratory hospitalizations (OFID)
• Evaluation of Oseltamivir used to prevent hospitalization in outpatients with influenza (JAMA)
• Pan-ebolavirus monoclonal antibody cocktail provides protection against Ebola and Sudan viruses (JID)
• Inappropriate antibiotic prescribing and its determinants among outpatient children in low-and middle-income countries (PLOS)
• IDSA 2023 Guidance on the treatment of antimicrobial resistant gram-negative infections (IDSA)
• Evaluating antimicrobial duration for gram-negative bacteremia in patients with neutropenia (TID)
• Antibiotic myths for the ID clinician (CID)
• Dalbavancin for the treatment of acute bacterial skin and skin structure infection in patients with obesity or Diabetes (OFID)
• Global differences in the management of S. aureus bacteremia (CID)
• Clinical risk Scores to Predict Trimethoprim-Sulfamethoxazole, Fluoroquinolone, Nitrofurantoin, and Cephalosporin non-susceptibility among outpatient episodes of complicated UTI among adults (OFID)
• Continuous vs intermittent meropenem administration in critically ill patients with sepsis (JAMA)
• Current pyuria cutoffs promote inappropriate UTI diagnosis in older women (CID)
• Paenibacillus infection as a novel cause of sepsis in term neonates with high risk of sequelae in Uganda (CID)
• Antimicrobial for 7 or 14 Days for febrile urinary tract infection in men (CID)
• Candida auris‒associated hospitalizations (EID)
• Fatal invasive mold infections after transplantation of organs recovered from drowned donors (EID)

Music is by Ronald Jenkees

On episode #30 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/24 – 6/7/23.

Hosts: Daniel Griffin and Sara Dong

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• Foodborne illness outbreaks at retail food establishments (CDC)
• Donor-derived fulminant herpes simplex virus hepatitis after liver transplantation (TID)
• High-dose influenza vaccine is associated with reduced mortality among older adults with breakthrough influenza (CID)
• Letermovir vs valganciclovir for prophylaxis of cytomegalovirus in high-risk kidney transplant recipients (JAMA)
• Association between combination antibiotic therapy as opposed as monotherapy and outcomes of ICU patients with pneumonia (CC)
• Safety of Streptococcus pyogenes vaccines (CID)
• Meningococcal ACWYX conjugate vaccine in 2 to 29 year olds (NEJM)
• Orthopaedic surgical management of pressure-ulcer related pelvic osteomyelitis (OFID)
• On culture and blood cultures (CMI)
• Benchmarking of outpatient pediatric antibiotic prescribing (JPIDS)
• Outbreak of suspected fungal meningitis in US patients who underwent surgical procedures under epidural anesthesia (CDC)
• Risk of systemic fungal infections after exposure to wildfires (The Lancet)
• Giardia duodenalis and dysentery in Iron Age Jerusalem (Parastiology)
• Community water fluoridation levels to promote effectiveness and safety in oral health (CDC)

Music is by Ronald Jenkees

On episode #29 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/11 – 5/23/23.

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• Harmonie phase IIIb study trial results of nirsevimab against RSV lower respiratory tract infection hospitalization for infants (ESPID)
• Mogamulizumab for treatment of HTLV-1 associated Myelopathy/Tropical Spastic Paraparesis (IDSA)
• Revised protocol for secondary prevention of congenital cytomegalovirus infection with valaciclovir (IDSA)
• Increase in false positive fourth generation HIV tests in patients with COVID-19 (CID)
• Implementation of an antibiotic stewardship initiative in a large urgent care network (JAMA)
• Clindamycin + vancomycin versus linezolid for treatment of necrotizing soft tissue infection (OFID)
• Assessing empiric antimicrobial therapy with the dundee classification for skin and soft tissue infections (OFID)
• Combination of amoxicillin 3000mg and probenecid vs 1500mg amoxicillin monotherapy for treating syphilis in patients with HIV (CID)
• The sympathetic nervous system is necessary for development of CD4+ T cell memory following Staphylococcus aureus infection (JID)
• Efficacy and safety of sulbactam-durlobactam versus colistin for the treatment of patients with infections caused by Acinetobacter baumannii-calcoaceticu complex (The Lancet)
• First reported US cases of tinea caused by Trichophyton indotineae (CDC)
• How to use direct microscopy for diagnosing fungal infections (CMI)
• Limited Cutaneous Leishmaniasis as Ulcerated Verrucous Plaque on leg (EID)
• Can Ivermectin kill Sarcoptes scabiei during the molting process? (PLOS)
• The Infectious Diseases Specialist, at risk of extinction (JID)
• Ticks harbor and excrete chronic wasting disease prions (NIH)

Music is by Ronald Jenkees