Less of You: Life on Semaglutide & Tirzepatide

Kami is five days into recovery from a balloon sinuplasty and turbinate reduction, and it has been brutal — she’s too congested to wear her CPAP, she can’t use her mouth guard while mouth-breathing all night, and she’s up every hour drinking water. Before any of that came up, though, she showed off three new waist-length hair extension colors, Foxy, Aurora, and Paprika, from Wildcrafted Beauty.

Eva turns Kami’s rough week into a bigger point from her five years surveying surgery patients: people who are prepared for both the recovery and the price end up far happier than people handed a stack of paperwork and sent home. Then she tops it with her own chaotic night — a lice outbreak that sent her and her daughters to a walk-in lice clinic, a neighbor’s warning text, and a mobile lice technician who showed up ten minutes after they got home and combed everything out by hand.

Eva also explains why nobody can tell she had a recent skin treatment: it’s the paper towel effect — you can pull dozens of sheets off a fresh roll before it looks any smaller, and subtle cosmetic work and early weight loss both hide the same way. The flip side: her lower face now looks years younger than the top half, which is making her overdue Botox and untouched forehead lines stand out more than ever.

Kami’s down six pounds on a lower GLP-1 dose and isn’t sure anyone will notice yet, which turns into a debate about Kelly Osbourne’s dramatic transformation and how far is too far. They also flag a telehealth ordering hiccup a listener caught for them (already being fixed) before teasing next episode’s guest, a designer named Lucy Darling.

Questions answered by this episode

1. What does recovery from a balloon sinuplasty and turbinate reduction actually feel like?
2. Why can’t you wear a CPAP machine right after nasal surgery?
3. Why is it important for a doctor to prepare patients for both recovery and cost before surgery
4. What should you do if you find lice in your child’s hair?
5. Are mobile lice removal services worth it?
6. What is the “paper towel effect” in weight loss and cosmetic changes?
7. How much weight do you have to lose before people actually notice?
8. What happens when someone loses too much weight on GLP-1 medications?

Follow us on Instagram: @lessofyoupodcast

Save 10% on weight-loss meds and peptides through our partner EpixNxt with code LESSOFYOU10.

Got a Skinny Shot Story of your own? Eva wants to hear it at skinnyshotstories.com. If you're a doctor interested in sponsoring this or any Axis cosmetic surgery and weight-loss podcast, visit lessofyou.com.

Less of You is a production of The Axis.

Host: Eva Sheie & Kami Gamlem
Assistant Producer: Mary Ellen Clarkson
Engineering: Victoria Cheng
Theme music: Old Grump, Smartface

Eva marched a Stephen King-grade demon clown costume up to the register in a store for kids — and when the manager disagreed that it didn’t belong there, she bought $50 Boden sneakers  out of spite for the place. Weeks later, her 6-year-old still won't go to the bathroom alone, because in her mind, the clown lives there now.

Kami, meanwhile, rides the high of the biggest legal win of her life — a court ruling that her former broker owes her over $6k in commission, plus attorney's fees, after she represented herself start to finish. She's 46 and had never set foot in a courtroom before this case, and is already plotting how to pay it forward with a giveaway once the check actually clears.

Eva's face is healing beautifully from her Junera laser treatment (thank-you sneakers included, minus the promised hot-pink laces), and she opens up about the financial advisor who finally got her out of feast-or-famine bookkeeping — plus the story of an offhand comment she made years ago that changed a friend's entire career path into trauma therapy.

Questions answered by this episode

• What is post-performance blues and why does it happen after a big presentation? 
• Can you win a small claims court case without hiring an attorney? 
• How long does it take skin to fully heal and tighten after a laser treatment?
• What does a fractional CFO actually do for a small business owner?
• How do you help a child who's scared of a Halloween costume or scary mask?
• Is there a real link between ADHD and a strong sense of justice?
• How much interest can you collect on a small claims judgment?

Follow us on Instagram: @lessofyoupodcast

Save 10% on weight-loss meds and peptides through our partner EpixNxt with code LESSOFYOU10.

Got a Skinny Shot Story of your own? Eva wants to hear it at skinnyshotstories.com. If you're a doctor interested in sponsoring this or any Axis cosmetic surgery and weight-loss podcast, visit lessofyou.com.

Less of You is a production of The Axis.

Host: Eva Sheie & Kami Gamlem
Assistant Producer: Mary Ellen Clarkson
Engineering: Victoria Cheng
Theme music: Old Grump, Smartface

Eva hadn't budged from 186 for a year and a half — until she stepped on it this week and saw 180, a number she hasn't seen in ages, ice cream summer in Washington included.

Kami has her own update: three pounds down in her fourth week of GLP-1 shots, plus a blunt reality check on the gastrointestinal side effects nobody warns you about (chewable laxatives included).

Swerving into real life, Kami searches an elderly neighbor's house for his missing 14-year-old cat after he is found on his floor, dehydrated and confused, having fallen some unknown number of days earlier.

Eva also gives a 17-day update on her recent face laser and submental lipo (still a little swollen, still a little numb) and talks through the tricky conversation of watching her daughter start to notice her own changing body during swim season.

Questions answered by this episode

1. How long does it take to see weight loss results on a GLP-1 medication?
2. What GI side effects are common when starting a GLP-1, and how do you manage them?
3. Does increasing your GLP-1 dose too quickly cause more side effects?
4. Is facial numbness normal after a facelift and neck liposuction?
5. How long does numbness last after facial plastic surgery?
6. How do you talk to a child about their changing body without creating body image issues?
7. Why might a doctor ask you to weigh in for a procedure unrelated to weight?
8. What magnesium supplements help with GLP-1-related constipation?

Help us keep this podcast going! When you order your weight loss meds or peptides through our partner at EpixNXT, we get a few dollars and you get 10% off with the code LESSOFYOU10 at epixNXT.com  

Less of You is a candid, funny, no-filter conversation between friends about weight loss, GLP-1 medications, aging, and everything that comes with trying to take care of yourself in real life.

Follow us on Instagram @lessofyoupodcast

Are you confronting the same challenges and have a story to tell? Share it on the Skinny Shot Stories podcast at skinnyshotstories.com

If you're a doctor and would like to learn more about sponsoring this or any of our cosmetic surgery and weight loss podcasts, go to lessofyou.com

Less of You is a production of The Axis: theaxis.io

Host: Eva Sheie & Kami Gamlem
Assistant Producer: Mary Ellen Clarkson
Engineering: Victoria Cheng
Theme music: Old Grump, Smartface

Three weeks after her Halo resurfacing, Eva decides to take the opportunity to have a Junera laser treatment, a new technology that treats the skin from within to tighten the face and neck from the inside. 

On the morning before heading to Dr. Jennifer Walden’s office in Austin, she took her before photos seriously: the 6:43 AM bathroom pictures, the long-stoplight car selfie video, the in-office clinical photos. 

Then two pills, a grid drawn on her face, almost falling while putting on socks, nitrous held by Jenny (“Feels like high school, huh?”), and a new perspective on what a great surgeon looks like and what it means to be a patient. Swelling peaks at 72 hours, and by day 10 the befores and afters look glorious. The great reveal comes next week.

Kami has her own procedure brewing. After 14 years of sleep apnea, an insurance company demanding a sleep study from a clinic on the other side of the country, and a scope that couldn’t even get up one nostril — 80% closed on one side, 90% on the other — scheduled for in Indianapolis booked her for turbinate reduction and balloon sinuplasty, with a real shot at ditching the CPAP for good.


Questions answered by this episode

1. What is the Junera laser and how does it work?
2. Does Junera laser skin tightening hurt?
3. What kind of sedation is used for minimally invasive laser procedures?
4. How long does swelling last after a Junera treatment?
5. Can you tighten loose neck skin after major weight loss without a facelift?
6. What is balloon sinuplasty?
7. What are turbinates and why do they stay swollen?
8. Does losing weight cure sleep apnea?
9. Can fixing a blocked nose get you off a CPAP machine?

Follow us on Instagram: @lessofyoupodcast

Save 10% through our partner EpixNxt with code LESSOFYOU10.

Co-hosts: Eva Sheie & Kami Gamlem
Assistant Producer: Mary Ellen Clarkson
Engineering: Victoria Cheng
Theme music: Old Grump, Smartface

Less of You is a production of The Axis.

After an important discussion about the microwave (also known as the micro-wah-vay), we theorize that GLP-1s are basically commoditized now. 

Meanwhile, to fix the microwave door, Eva's husband drove actual screws through it (that’s not how microwaves work) and we get an update on Kami's small claims case against her former broker.

Eva considers an unexpected opportunity to get her very loose turkey neck skin fixed with the new Junera laser, which was at the top of the wish list someday, and now that day is next Monday.

Kami reports back on her first EpixNxt order and walks through the whole thing: a thorough intake form, telemedicine approval, and a tracking number in under a day — coming in around $125 a month, less than the $170–$300 the local compounding pharmacies quoted.

Questions answered by this episode

1. Why are compounded GLP-1 medications getting cheaper?
2. How do online tirzepatide prices compare to a local compounding pharmacy?
3. If I've been off a GLP-1 for months, how should I restart my dose?
4. What is the Junera laser and can it tighten loose neck skin after weight loss?
5. Is loose skin on the neck caused by weight loss or genetics?

Follow us on Instagram: @lessofyoupodcast

Save 10% through our partner EpixNxt with code LESSOFYOU10.

Co-hosts: Eva Sheie & Kami Gamlem
Assistant Producer: Mary Ellen Clarkson
Engineering: Victoria Cheng
Theme music: Old Grump, Smartface

Less of You is a production of The Axis.

After Eva went in for Halo laser resurfacing with a friend (who happens to be one of the best in the world), she walked out looking horrifying (according to the 8 year old) then drove straight to a dance recital tearing a cooling mask in half and swapping it between cheeks.

She’s back with the whole before-and-after saga: the time-lapse, the nitrous oxide she thought she wouldn’t need, a wicked fever-blister flare, and ten full seconds of obsessing over her jawline.

An opportunity to do Junera came up — a thin, spaghetti-like fiber laser that works under the skin to melt a little fat and tighten the jaw and neck, which happens August 10.

Kami placed her first EpixNxt order for tirzepatide, coupon code and all, with an unboxing and an honest weigh-in coming next week. Eva weighs a switch from her compounded progesterone pill to the injectable version, and the two compare notes on why injections beat pills and how gummies and chewable magnesium became dessert.

Eva’s kids head to a brand-new school with nine kids per class after a rough kindergarten year, and Kami’s daughter starts the high-ability track — plus a Barbie convention where Eva met the woman who designed Barbie’s clothes for three decades, still holding court in her 90s on a scooter. Kami signs off with a cliffhanger about her lawsuit.

Questions answered by this episode

1. What is recovery from a Halo laser resurfacing actually like, day by day?
2. Why do laser providers offer nitrous oxide during a resurfacing treatment?
3. Can a laser skin treatment trigger a cold sore or fever-blister flare?
4. What is Junera, and how does a subdermal laser tighten the jaw and neck?
5. What is it like to be a training or model patient for a new aesthetic device?
6. How does ordering weight-loss medication like tirzepatide through EpixNxt work?
7. Can you switch from a compounded progesterone pill to injectable progesterone?
8. Why do some people end up preferring injections over pills for hormones and GLP-1s?

Follow us on Instagram: @lessofyoupodcast

Save 10% on weight-loss meds and peptides through our partner EpixNxt with code LESSOFYOU10.

Co-hosts: Eva Sheie & Kami Gamlem
Assistant Producer: Mary Ellen Clarkson
Engineering: Victoria Cheng
Theme music: Old Grump, Smartface

Less of You is a production of The Axis.

After an accidental three-and-a-half-month hiatus, we are back with updates and committing to every week. We catch up on  kids, summer camps, GLP-1 dosing and pricing, HRT and perimenopause, peptides, and one genuinely scary night at the tennis court.

Eva shares what she learned digging into the GLP-1 market, from the shell-website pharmacies to the discovery that most of them source from the same distributor, and how she finally found an affordable telehealth source she trusts that also ships fast and costs a fraction of what she used to pay.

Kami shares how backing off her dose and starting HRT collided with perimenopause rage, and why she's rebuilding her plan around her budget instead of the scale.

A heat-stroke scare at Sunday-night tennis turns into a talk about not eating all day to lose weight, a running debate about how much protein a person can actually stomach, and the usual detour through their kids, from cupcake camp to a very memorable definition of "making love."

Help us keep this podcast going! When you order your weight loss meds or peptides through our partner at EpixNXT, we get a few dollars and you get 10% off with the code LESSOFYOU10 at epixNXT.com  

Get your meds and support the show: epixNXT.com  (use our code LESSOFYOU10 for 10% off)

Less of You is a candid, funny, no-filter conversation between friends about weight loss, GLP-1 medications, aging, and everything that comes with trying to take care of yourself in real life.

Follow us on Instagram @lessofyoupodcast

Are you confronting the same challenges and have a story to tell? Share it on the Skinny Shot Stories podcast at skinnyshotstories.com

If you're a doctor and would like to learn more about sponsoring this or any of our cosmetic surgery and weight loss podcasts, go to lessofyou.com

Less of You is a production of The Axis: theaxis.io

Kami goes off her GLP-1, stops her thyroid meds, and gains back 25 lbs. After 3 months of Eva being angry for no reason, it turns out she just needs hormones.

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & updated regularly at lessofyou.com

To learn more about sponsoring this or for details on advertising opportunities on our cosmetic surgery and weight loss podcasts, request more info at theaxis.io. 

Follow us on Instagram @lessofyoupodcast 

Co-hosts: Eva Sheie & Kami Gamlem
Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart
Engineering: Victoria Cheng
Theme music: Old Grump, Smartface

Less of You is a production of The Axis

Kami runs out of weight loss meds during the holidays, gains 10 pounds, and blames the dryer for shrinking her clothes. Eva overschedules everything, battles inconsistent clothing sizes at fancy events, and gets unsolicited body size comments at work.

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & updated regularly at lessofyou.com

To learn more about sponsoring this or for details on advertising opportunities on our cosmetic surgery and weight loss podcasts, request more info at theaxis.io. 

Follow us on Instagram @lessofyoupodcast 

Co-hosts: Eva Sheie & Kami Gamlem
Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart
Engineering: Victoria Cheng
Theme music: Old Grump, Smartface

Less of You is a production of The Axis

Eva gets ghosted in the middle of an important situation and spirals for a day. Kami stops her meds and finds out what it feels like to be hungry again after two years.

Check out Murderland: Crime and Bloodlust in the Time of Serial Killers

Shop Shapermint

Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. 

Are you confronting the same challenges? We’d love to hear your story. Send an email to [email protected].

To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & updated regularly at lessofyou.com

To learn more about sponsoring this or for details on advertising opportunities on our cosmetic surgery and weight loss podcasts, request more info at theaxis.io. 

Follow us on Instagram @lessofyoupodcast 

Co-hosts: Eva Sheie & Kami Gamlem
Assistant Producers: Mary Ellen Clarkson & Hannah Burkhart
Engineering: Victoria Cheng
Theme music: Old Grump, Smartface

Less of You is a production of The Axis 

This episode includes AI-generated content.