October 07, 2025

Mayim Bialik on Anxiety, Recovery & Resilience | Season 14 Premiere

54 minutes

Welcome to Season 14 of Sh!t That Goes On In Our Heads—and we’re opening with a powerhouse: Mayim Bialik. You know her from Blossom, The Big Bang Theory, and Jeopardy!, but in this conversation, she steps off the stage lights and speaks from the heart.

This podcast is proud to be a 2024 People’s Choice Podcast Award winner (Best Health) and the 2024 Women in Podcasting Award winner (Best Mental Health Podcast). With over 2 million downloads, we’re building a global community where mental health conversations are real, raw, and stigma-free.

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Quote of the Episode:

"No one is alone. And even when we feel alone, there is always a lifeboat." – Mayim Bialik

Episode Description

In this powerful Season 14 opener, Mayim Bialik gets real about what it was like growing up on Blossom, navigating the pressures of fame, and surviving the harsh criticism that came with life in the spotlight. She opens up about the insecurities behind her confident on-screen characters, the mental health struggles she faced as a teen actor, and the ongoing journey of therapy and self-discovery. We dive into conversations around anxiety, depression, and the stigma of speaking openly about mental illness—especially in families where silence was the norm.

Mayim also shares why she started her own podcast, Bialik’s Breakdown, and how her PhD in neuroscience inspired her mission to make mental health conversations more accessible. We explore topics like codependency, addiction, spirituality, and the small joys that keep her grounded (spoiler: cats, cooking, and stickers make the list). From advice for teenagers who feel out of place to the importance of borrowing someone else’s faith in you when your own runs out, this episode is full of wisdom, humor, and raw humanity.

It’s not just a celebrity interview—it’s a masterclass in being human, messy and all.

Meet Our Guest — Mayim Bialik

Mayim Bialik is best known for her lead role as Blossom Russo in the early-1990s NBC television sitcom Blossom. She played the role of Amy Farrah Fowler on the critically acclaimed CBS comedy, The Big Bang Theory, a role for which she received 2 Critics’ Choice Award wins, 4 Emmy nominations and a SAG Award nomination. She served as host of Jeopardy! for 2 seasons, earning her fifth Emmy nomination for her contributions to the iconic show, which won its first Primetime Emmy the year she hosted.

In 2021, Bialik wrote and directed the feature film As They Made Us, starring Dustin Hoffman, Candice Bergen, Dianna Agron, and Simon Helberg. She hosts the popular mental health podcast Mayim Bialik’s Breakdown, which has garnered over 60 million downloads.

Bialik holds a BS and PhD in Neuroscience from UCLA, and she has authored four books, two of which are New York Times Bestsellers: "Girling Up: How to Be Strong, Smart, and Spectacular" and "Boying Up: How to Be Brave, Bold, and Brilliant."

Socials:

Instagram: https://instagram.com/missmayim

Substack: https://bialikbreakdown.substack.com/

Podcast IG: https://instagram.com/bialikbreakdown

Why Mayim matters:

This woman is a force. From Blossom to The Big Bang Theory to Jeopardy! to directing films, Mayim’s résumé is stacked—but what makes her matter here is her willingness to get honest about the hard stuff. She has taken her scientific brain, her Hollywood grit, and her own lived experiences to open up conversations that make people feel less alone. That’s the kind of guest who doesn’t just inspire—you feel her words.

Key Takeaways

Being “quirky” or different doesn’t go away—it just bothers you less with time.

Mental health isn’t one-size-fits-all; healing looks different for everyone.

Secrets keep us sick—honesty and vulnerability are the keys to connection.

Fame doesn’t shield anyone from insecurity or anxiety.

Joy often comes from the small, simple things—like cooking, cats, or stickers.

Borrowing someone else’s faith in you can be the lifeline you need.

Actionable Items

Start a gratitude practice—list three small things daily that bring you joy.

If you’re struggling, try “speed-dating therapists” until you find one who’s the right fit.

Drop the shame: share your truth with someone you trust—you’re only as sick as your secrets.

References Mentioned

NAMI (National Alliance on Mental Illness): https://nami.org

Mayim Bialik’s Breakdown Podcast: https://www.bialikbreakdown.com

Whitney Cummings (on codependency): https://whitneycummings.com

Important Chapters

[00:02:00] Blossom Days – Mayim opens up about the groundbreaking role and how it shaped conversations on TV.

[00:06:15] Tackling Heavy Topics – Behind the scenes of handling episodes on consent, drugs, and family dynamics.

[00:15:00] Starting a Mental Health Podcast – Why Mayim launched Bialik’s Breakdown.

[00:22:00] Breaking Family Silence – From secrecy to speaking openly about mental health and recovery.

[00:36:10] Advice for Young Girls – Wisdom for teens who feel different, bullied, or alone.

[00:50:00] Borrowing Faith – How the belief of others carried Mayim through tough times.

Closing CTA

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#MentalHealthPodcast #MentalHealthAwareness #Grex #DirtySkittles #Podmatch #MayimBialik #BialikBreakdown #MentalHealthMatters #Neuroscience #BigBangTheory #BlossomTV #TherapyTalk #HealingJourney #MentalHealthCommunity #BreakingStigma #SelfCompassion #BeKind #PodcastSeason14

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If You Need Support, Reach Out

If you or someone you know is facing mental health challenges, please don’t hesitate to reach out to a crisis hotline in your area. Remember, it’s OK not to be OK—talking to someone can make all the difference.

United States: Call or Text 988 — 988lifeline.org
Canada: Call or Text 988 — 988.ca
Worldwide: Find a Helpline
Mental Health Resources and Tools: The Help Hub

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