<a target="_blank" href="https://www.buzzsprout.com/twilio/text_messages/1535644/open_sms">Send us a text</a>Dr. John Speakman is a biologist whose research focuses on energy balance, energy expenditure, genetic and environmental drivers of obesity and the energetic contribution to aging. They discuss: the history of the obesity epidemic in the US vs. China; changes in patterns of physical activity, diet, and energy expenditure in humans over time; how saturated fats vs. PUFAs affect basal metabolism; the relative contributions of fats, carbs, and protein to fat & weight gain; and more. *Not medical advice. <a rel="payment" href="https://mindandmatter.substack.com/p/how-to-support-mind-and-matter">Support the show</a>All episodes, show notes, transcripts, and more at the <a href='https://mindandmatter.substack.com/'>M&M Substack</a> Affiliates: <ul> <li> <a href='https://santabarbaranutrients.com/products/ketocitra'>KetoCitra</a>—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)</li> <li> <a href='https://www.lumen.me/shop?fid=8731&discount=MINDMATTER'>Lumen device</a> to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off</li> <li> <a href='https://readwise.io/nickjikomes/'>Readwise</a>: Organize and share what you read. 60 days FREE through link</li> <li> <a href='https://siphoxhealth.com/?sca_ref=5338127.lZ39LNbYg8'>SiPhox Health</a>—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount.</li> <li> <a href='https://www.masachips.com/discount/MIND'>MASA Chips</a>—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off</li> </ul> For all the ways you can <a href='https://mindandmatter.substack.com/p/how-to-support-mind-and-matter'>support my efforts</a>

Send us a text Dr. John Speakman is a biologist whose research focuses on energy balance, energy expenditure, genetic and environmental drivers of obesity and the energetic contribution to aging. They discuss: the history of the obesity epidemic in the US vs. China; changes in patterns of physical activity, diet, and energy expenditure in humans over time; how saturated fats vs. PUFAs affect basal metabolism; the relative contributions of fats, carbs, and protein to fat & weight gain; and more. *Not medical advice. Support the show All episodes, show notes, transcripts, and more at the M&M Substack Affiliates: KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off Readwise: Organize and share what you read. 60 days FREE through link SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off For all the ways you can support my efforts

<a href="https://www.buzzsprout.com/twilio/text_messages/1535644/open_sms" rel="noopener noreferrer">Send us a text</a>Dr. John Speakman is a biologist whose research focuses on energy balance, energy expenditure, genetic and environmental drivers of obesity and the energetic contribution to aging. They discuss: the history of the obesity epidemic in the US vs. China; changes in patterns of physical activity, diet, and energy expenditure in humans over time; how saturated fats vs. PUFAs affect basal metabolism; the relative contributions of fats, carbs, and protein to fat &amp; weight gain; and more. *Not medical advice. <a href="https://mindandmatter.substack.com/p/how-to-support-mind-and-matter" rel="noopener noreferrer">Support the show</a>All episodes, show notes, transcripts, and more at the <a href="https://mindandmatter.substack.com/" rel="noopener noreferrer">M&amp;M Substack</a> Affiliates: <ul> <li> <a href="https://santabarbaranutrients.com/products/ketocitra" rel="noopener noreferrer">KetoCitra</a>—Ketone body BHB + potassium, calcium &amp; magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)</li> <li> <a href="https://www.lumen.me/shop?fid=8731&amp;discount=MINDMATTER" rel="noopener noreferrer">Lumen device</a> to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off</li> <li> <a href="https://readwise.io/nickjikomes/" rel="noopener noreferrer">Readwise</a>: Organize and share what you read. 60 days FREE through link</li> <li> <a href="https://siphoxhealth.com/?sca_ref=5338127.lZ39LNbYg8" rel="noopener noreferrer">SiPhox Health</a>—Affordable at-home blood testing. Key health markers, visualized &amp; explained. Code TRIKOMES for a 20% discount.</li> <li> <a href="https://www.masachips.com/discount/MIND" rel="noopener noreferrer">MASA Chips</a>—delicious tortilla chips made from organic corn &amp; grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off</li> </ul> For all the ways you can <a href="https://mindandmatter.substack.com/p/how-to-support-mind-and-matter" rel="noopener noreferrer">support my efforts</a>

Obesity Epidemic, Metabolism, Saturated Fat vs. PUFAs, Energy Expenditure, Weight Gain & Feeding Behavior | John Speakman | 132

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists &amp; thinkers alive today about how your mind-body reacts to what you feed it. The weekly <a href="https://mindandmatter.substack.com/podcast?sort=top">M&amp;M podcast</a> features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&amp;M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body &amp; mind work by curating &amp; synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: <ul><li><a href="https://mindandmatter.substack.com/p/the-psychiatry-of-metabolism">Taking ownership of your health starts with taking ownership of your information diet</a>.</li><li>All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas &amp; preferred conclusions.</li><li>Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but <a href="https://mindandmatter.substack.com/p/what-is-psychological-dissociation-78d">pain is information.</a></li></ul> Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload &amp; historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: <ul><li>“Γνῶθι σεαυτόν” (Know thyself)</li><li>“Μηδὲν ἄγαν” (Nothing in excess)</li><li>“Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)</li></ul>

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Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it. The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body & mind work by curating & synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: Taking ownership of your health starts with taking ownership of your information diet.All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas & preferred conclusions.Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but pain is information. Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload & historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: “Γνῶθι σεαυτόν” (Know thyself)“Μηδὲν ἄγαν” (Nothing in excess)“Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists &amp; thinkers alive today about how your mind-body reacts to what you feed it. The weekly <a href="https://mindandmatter.substack.com/podcast?sort=top" rel="noopener noreferrer">M&amp;M podcast</a> features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today. Not medical advice. At M&amp;M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so be it. As the host, my aim is to help you better understand how the body &amp; mind work by curating &amp; synthesizing information in a way that yields science-based insights that you can choose to use or disregard in your own life. Taking ownership of your health starts with taking ownership of your information diet. I am motivated to connect the dots and distill general principles from what I learn, preferring to ask questions and play devil’s advocate to debating or incessantly pushing my own viewpoint. My beliefs: <ul><li><a href="https://mindandmatter.substack.com/p/the-psychiatry-of-metabolism" rel="noopener noreferrer">Taking ownership of your health starts with taking ownership of your information diet</a>.</li><li>All knowledge is provisional and we must work hard to prevent ourselves from becoming attached to our favorite ideas &amp; preferred conclusions.</li><li>Wisdom comes from an iterative, trial-and-error process of learning and unlearning. Letting go of pre-conceived notions can be painful, but <a href="https://mindandmatter.substack.com/p/what-is-psychological-dissociation-78d" rel="noopener noreferrer">pain is information.</a></li></ul> Sometimes modern discoveries teach us we must unlearn received wisdom. Other times, modern information overload &amp; historical chauvinism cause us to forget ancient wisdom which stills applies. The framework for learning that I embody is inspired by three Ancient Greek maxims inscribed in the Temple of Apollo at Delphi: <ul><li>“Γνῶθι σεαυτόν” (Know thyself)</li><li>“Μηδὲν ἄγαν” (Nothing in excess)</li><li>“Ἐγγύα πάρα δ Ἄτα” (Certainty brings insanity)</li></ul>

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Obesity Epidemic, Metabolism, Saturated Fat vs. PUFAs, Energy Expenditure, Weight Gain & Feeding Behavior | John Speakman | 132

Obesity Epidemic, Metabolism, Saturated Fat vs. PUFAs, Energy Expenditure, Weight Gain & Feeding Behavior | John Speakman | 132

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