Podcast Notes Playlist: Latest Episodes

Podcast Notes Playlist: Latest Episodes

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Podcast Notes Playlist: Latest Episodes episodes

  • #143 Andrew Wilkinson: Entrepreneurial Insights
    Knowledge Project


    Podcast Notes Key Takeaways
    • Mimetic desire: whatever the people you surround yourself with want, you end up wanting as well, i.e. being subconsciously driven to achieve external validation rather than intrinsic validation 
    • The constant desire to want to improve parts of your life or business turns your weaknesses into strengths
    • “Most successful people are just an anxiety disorder harnessed for productivity” – Andrew Wilkinson 
    • Andrew focuses on building businesses that do not compete with venture capital and whose success can be predicted with reasonable certainty 
    • Andrew applies the “80/20 rule” to learning about health; spend an hour a month reading all of the scientific summaries and then don’t think about it again
    • On raising kids with wealth: “At the end of the day, your kids just need to know that you’re there and you love them, and I hope that’s enough.” – Andrew Wilkinson
    • The Concept of Self-Binding: create an environment where you can’t do the things you don’t want to do, such as eating ice cream, by removing the stimulus from your environment completely
    • The unconscious mind is far more powerful than the conscious mind 


    Read the full notes @ podcastnotes.org



    Canadian businessman and billionaire investor Andrew Wilkinson has made a successful career out of channeling his entrepreneurial spirit, but he knows that sometimes that energy can be a double-edged sword. On this episode, Wilkinson goes in-depth on the lessons learned from a career that’s seen him build a business empire of more than 40 companies, but also why he’s had to re-calibrate his personal goals after struggling to find happiness in the summer of 2021. He also discusses mimetic desire, building a business in a small Canadian market, competing with venture-backed companies, strategies for hiring CEOs, the mistakes that have cost him millions of dollars, and so much more.   Wilkinson is the co-founder of Tiny Capital, which boasts an enterprise value of more than $1 billion and owns 35 different companies including AeroPress, MetaLab and Dribble. He is also the co-founder and chairman of WeCommerce, a holding company that starts, buys, and invests in the world’s top Shopify businesses. He is based in Victoria, British Columbia.
    --

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    Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

    1 hr 16 min
  • The Science & Treatment of Bipolar Disorder | Episode 82
    In this episode, I explain the biology, symptoms, causes and types of bipolar disorder (sometimes called bipolar depression). I discuss neuroplasticity and how the brain normally regulates mood, energy, and perceptions; then, I contrast that with the biology of bipolar disorder, which is characterized by extremes of energy and mood, e.g., mania and depression. I outline the mechanisms through which bipolar disorder manifests in the brain, including deficits of interoception and reduced connections between the parietal and limbic systems. I also outline how treatment options (such as lithium) work in part through homeostatic plasticity.’ I discuss not only lithium but also the treatment of bipolar with ketamine, different talk therapies, electroconvulsive therapy, transcranial magnetic stimulation, and nutraceuticals, including Omega-3 and Inositol supplementation. This episode should interest anyone who has or knows someone with bipolar disorder and, more broadly, those interested in how the brain works to create a balance between thoughts, energy levels, focus, and mood.
    Thank you to our sponsors
    InsideTracker: https://insidetracker.com/huberman
    ROKA: https://roka.com/huberman
    Blinkist: https://www.blinkist.com/huberman
    Supplements from Momentous
    https://www.livemomentous.com/huberman.
    For the full show notes, visit hubermanlab.com.
    Timestamps
    (00:00:00) Bipolar Disorder
    (00:02:23) Momentous Supplements
    (00:03:42) Tool: Appetite Suppression & GLP-1, Parallel Pathways, Yerba Mate
    (00:10:23) InsideTracker, ROKA, Blinkist
    (00:14:24) Prevalence & Severity of Bipolar Disorder
    (00:16:30) Bipolar Disorder I, Diagnostic Criteria of Mania
    (00:28:58) Bipolar Disorder II, Individual Variability
    (00:33:07) Bipolar I vs. Bipolar II: Manic, Depressive & Symptom-Free States
    (00:38:20) Consequences of Bipolar Disorder, Heritability
    (00:46:53) Bipolar Disorder vs. Borderline Personality Disorder
    (00:51:51) Mania & Depression, Negative Impacts
    (00:53:06) History of Lithium Treatment
    (01:02:44) Lithium Treatment & Side-Effects
    (01:05:05) Effects of Lithium: BDNF, Anti-inflammatory & Neuroprotection
    (01:10:10) Neural Circuits of Bipolar Disorder, Interoception, Hyper- vs. Hypoactivity
    (01:17:11) Neural States & Mania, Parietal Lobe & Limbic System
    (01:22:58) Homeostatic Plasticity, Synaptic Scaling, Lithium & Ketamine
    (01:36:00) Talk Therapies: Cognitive Behavioral Therapy, Family-Focused Therapy, Interpersonal & Social Rhythm Therapy
    (01:43:18) Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (rTMS)
    (01:48:01) Psylocibin, Cannabis
    (01:51:50) Lifestyle Support, Supplements: Inositol & Omega-3 Fatty Acids
    (02:03:31) Omega-3s, Membrane Fluidity & Neuroplasticity
    (02:06:44) Mania, Creativity & Occupations
    (02:15:33) Bipolar Disorder: Diagnosis, Neural Circuits & Treatment
    (02:17:45) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter
    Title Card Photo Credit: Mike Blabac
    Disclaimer
    2 hr 20 min
  • Salary Negotiation with Haseeb Qureshi
    Originally published on April 12, 2016. Negotiation is an important skill for software engineers. The salary you negotiate at the beginning of your job could be a difference of tens of thousands of dollars over the course of an engineer’s career, but intimidating recruiters and exploding offers scare many engineers from negotiating at all. Today,
    1 hr 33 min
  • Michael Saylor Interview: The Future of Bitcoin
    Bitcoin Magazine Podcast
    ✓
    Claim


    Podcast Notes Key Takeaways
    • Money and currency are two different things
      • Money is economic energy, while a currency is a method of moving economic energy across time and space that is typically designated by a government 
    • Fiat currencies are a method of moving economic energy, but they dissipate energy over time
      • For example, the US dollar dissipates energy at a rate of about 15% per year, and the Turkish Lira dissipates about 70% of its energy per year
    • Bitcoin could become a $250 trillion ecosystem without threatening any nation state by demonetizing gold, then real estate, then corporate bonds, equities, etc.
      • It doesn’t have to “replace” anything; it can partner with people, companies, and nations and improve them 
    • “If you want to watch how Bitcoin Hyperization happens, watch how dollarization happens … and does it happen with bloodshot or without bloodshed.” –  Michael Saylor
      • He doesn’t think it’s practical for the world to collectively adopt a Bitcoin standard anytime in the next few decades
    • As Bitcoin grows and becomes more understood, rational nations will embrace Bitcoin holders, miners, and companies, which will result in more favorable policies toward Bitcoin
    • “Sound money in the 19th century was gold. Sound money in the 21st century is bitcoin.” – Michael Saylor
      • Bitcoin is just the introduction of a better technology; it is not “coming to get” anyone or anything
    • There don’t have to be losers if Bitcoin adoption continues; everyone can win
      • Instead of “Bitcoin fixes this”, the more appropriate meme is “Bitcoin improves this”


    Read the full notes @ podcastnotes.org



    Michael Saylor (@Saylor) and Aleks Svetski (@GhostofSvetski) have a long-form conversation about the implications of Bitcoin and its effects on the world we live in today.

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    1 hr 13 min
  • Will Bitcoin Replace Central Banks with Lyn Alden
    What Bitcoin Did


    “I think this decade is going to be transformative, but we’re still too early to say exactly where this ends up or how quickly this goes.”

    — Lyn Alden

    SHOW DESCRIPTION

    Lyn Alden is a macroeconomist and investment strategist. In this interview, we discuss the rise and role of Central Banks: their intermittent role in the US’s history, the piecemeal erosion of a gold standard, the new era of easy money, and whether Bitcoin could replace Central Banking.

    - - - -

    Central Banks have played such a dominant role in our societies it’s easy to assume that they are required institutions within modern governmental systems. The idea that the market can determine a monetary policy and the price for money is well outside of the Overton window.

    Yet, for long periods in the industrialised era modern civilised societies have functioned, developed and prospered without such institutions. Further, there is ample evidence that central banks are now far from being a steadying force that brings stability to economies.

    For around 100 years, the international monetary system was pegged to gold; albeit there were debasements, new controls, and periodic abandonments during this period. Then in 1971, the monetary system was taken off any remnants of a gold standard. Its constraints on US fiscal policy had become too burdensome. It led to the development of fiat currencies and a period of easy money.

    Governments have become increasingly dependent upon Central Banks in creating new money to assist with economic shocks: following the global financial crisis the production of dollars markedly increased. But these events were dwarfed by the injection of new money during the pandemic. Inflation is now catching up, but at a time when economies are stagnating.

    Cycles of debt accumulation always come to an end. Without careful political judgement, coordination and luck, the resolution of unsustainable debt at the global level can lead to domestic and international conflict. So, we’re entering a transformative decade.

    The question is whether Bitcoin, the strongest form of money ever invented, can enable society to navigate through this unwinding of the long-term debt cycle? Additionally, can it enable the market to again determine the price of money?

    This episode’s sponsors:
    Gemini - Buy Bitcoin instantly
    BlockFi - The future of Bitcoin financial services
    Bitcasino - The Future of Gaming is here
    Pacific Bitcoin - Bitcoin‑only event, Nov 10 & 11, 2022
    Ledger - State of the art Bitcoin hardware wallet
    Compass Mining - Bitcoin mining & hosting
    Cake Wallet - Open-source, privacy-focused Bitcoin wallet
    BCB Group - Global digital financial Services


    -----

    WBD521 - Show Notes

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    1 hr 15 min
  • #171 – Anthony Pompliano: Bitcoin
    Anthony Pompliano is an entrepreneur, investor, writer, and podcaster on topics of decentralized finance. Please support this podcast by checking out our sponsors: – Theragun: https://theragun.com/lex to get 30 day trial – Sun Basket: https://sunbasket.com/lex and use code LEX to get $35 off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – Indeed: https://indeed.com/fridman to get $75 credit EPISODE LINKS: Anthony’s Twitter: https://twitter.com/APompliano Anthony’s YouTube: https://www.youtube.com/c/AnthonyPompliano Anthony’s Website: https://anthonypompliano.com/ Pomp Letter: https://pomp.substack.com/ Pomp Podcast: https://anthonypompliano.com/podcast/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT &
    3 hr 9 min
  • Dr. Charles Zuker: The Biology of Taste Perception & Sugar Craving | Episode 81
    My guest this episode is Dr. Charles Zuker, PhD, Professor of Biochemistry, Molecular Biophysics and Neuroscience at Colombia University and an Investigator with the Howard Hughes Medical Institute. Dr. Zuker is the world’s leading expert in the biology of taste, thirst and craving. His laboratory explores the mechanisms of taste perception, focusing on how our conscious and unconscious processing of specific foods and nutrients guide our actions and behaviors. We discuss the neural circuits of taste, the “gut-brain axis,” the basis of food cravings and the key difference between wanting (craving) and liking (perceiving) sugar. We also explore how taste perception relates to specific food satiety, thirst, to our emotions, and expectation. We also consider how sugar containing and highly-processed foods can hijack the natural balance of the taste and digestive systems. Dr. Zuker provides a true masterclass in the biology of taste and perception that ought to be of interest to anyone curious about how the brain works, our motivated behaviors and the neural, chemical perceptual aspects of the mind.
    Thank you to our sponsors
    Thesis: https://takethesis.com/huberman
    ROKA: https://roka.com/huberman
    Helix Sleep: https://helixsleep.com/huberman
    Supplements from Momentous
    https://www.livemomentous.com/huberman.
    For the full show notes, visit hubermanlab.com.
    Timestamps
    (00:00:00) Dr. Charles Zuker & Taste Perception
    (00:03:05) Momentous Supplements
    (00:04:35) Thesis, ROKA, Helix Sleep
    (00:08:35) Sensory Detection vs. Sensory Perception
    (00:11:48) Individual Variations within Perception, Color
    (00:16:20) Perceptions & Behaviors
    (00:20:19) The 5 Taste Modalities
    (00:26:18) Aversive Taste, Bitter Taste
    (00:28:00) Survival-Based & Evolutionary Reasons for Taste Modalities, Taste vs. Flavor
    (00:30:14) Additional Taste Modalities: Fat & Metallic Perception
    (00:34:02) Tongue “Taste Map,” Taste Buds & Taste Receptors 
    (00:39:34) Burning Your Tongue & Perception
    (00:42:54) The “Meaning” of Taste Stimuli, Sweet vs. Bitter, Valence
    (00:51:55) Positive vs. Negative Neuronal Activation & Behavior
    (00:56:16) Acquired Tastes, Conditioned Taste Aversion 
    (01:01:44) Olfaction (Smell) vs. Taste, Changing Tastes over One’s Lifetime
    (01:09:14) Integration of Odor & Taste, Influence on Behavior & Emotion
    (01:17:26) Sensitization to Taste, Internal State Modulation, Salt
    (01:24:05) Taste & Saliva: The Absence of Taste
    (01:28:10) Sugar & Reward Pleasure Centers; Gut-Brain Axis, Anticipatory Response
    (01:36:23) Vagus Nerve
    (01:43:09) Insatiable Sugar Appetite, Liking vs. Wanting, Gut-Brain Axis
    (01:52:03) Tool: Sugar vs. Artificial Sweeteners, Curbing Appetite
    (01:54:06) Cravings & Gut-Brain Axis 
    (01:57:30) Nutrition, Gut-Brain Axis & Changes in Behavior
    (02:01:53) Fast vs. Slow Signaling & Reinforcement, Highly Processed Foods 
    (02:10:38) Favorite Foods: Enjoyment, Sensation & Context
    (02:15:58) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter
    Title Card Photo Credit: Mike Blabac
    Disclaimer
    2 hr 18 min
  • Billion Dollar Business Philosophies With Hubspot Co-Founder Dharmesh Shah
    Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) talk to Co-Founder & CTO of HubSpot, Dharmesh Shah (@dharmesh), about why a bad economy is a good time to start a business, creating an alternative to Wordle, and the trillion dollar Venn diagram of success.
    Also, want $5,000? Check out the My First Million Clips contest.
    -----
    Links:
    * HubSpot
    * Why to Start a Startup in a Bad Economy article
    * WordPlay
    * Maven writing course
    * Shaan tweet about starting the next Pixar
    * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
    * Want more insights like MFM? Check out Shaan's newsletter.
    -----
    Show Notes:
    (02:10) - Why renting is better than owning
    (25:20) - Framework for three types of employees
    (35:05) - Why Dharmesh built WordPlay
    (01:07:55) - Driving value through an intersection of skills (Trillion dollar Venn diagram)
    (01:12:10) - Why Shaan is starting the next Pixar
    -----
    Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.
    -----
    Additional episodes you might enjoy:
    • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
    • #209 Gary Vaynerchuk - Why NFTS Are the Future
    • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
    #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
    • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates
    • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
    • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
    1 hr 32 min
  • The Next Founders
    There are nearly 4000 universities in the U.S.. Many of them have billions of dollars in endowments and histories that go back to well before the country's founding. So you'd be forgiven for thinking that it would be a bit ridiculous to try and compete with those Goliaths. 
    But that's exactly what the new University of Austin or UATX is doing. The premise, of course, is simple, and it goes like this. While the brand name schools have the money, they no longer have the mission. They have fundamentally abandoned the point of the university, which is the pursuit of truth. The good people at UATX, where I'm proud to be on the board, are not waiting for the broken status quo to change. They're not sitting around criticizing or whining. They are doing. 
    Just a few weeks ago, UTAX opened its doors to its first students at its inaugural summer school. I was blown away by the students that I met there, and I was honored to lecture alongside teachers like Neil Ferguson, Kathleen Stock, Ayaan Hirsi Ali, Rob Henderson and Thomas Chatterton Williams. And today I wanted to share with all of you the talk that I gave at the old parkland in Dallas to that first class of students. It's about the broken moment that we're in as a culture and a country, but more it's about what I think is required of us to meet this moment.
    Learn more about your ad choices. Visit megaphone.fm/adchoices
    46 min
  • #500 - Special: 18 Lessons From 500 Episodes
    Modern Wisdom


    Podcast Notes Key Takeaways
    • Check out the Modern Wisdom Episode Page & Show Notes


    Read the full notes @ podcastnotes.org



    To celebrate 500 episodes on Modern Wisdom, I broke down some of my favourite lessons, insights and quotes from the last 4 and a half years.

    Expect to learn why having no role models can be an advantage, how discipline eats motivation for breakfast, why you should be training for the difficult, why success in pursuit of happiness can be self-defeating, why fame makes you weak, how an obsession with productivity is just immortality by another name, what I learned about negativity biases from Margaret Thatcher, the importance of letting go of successful habits for new ones and much more...

    Sponsors:

    Join the Modern Wisdom Community to connect with me & other listeners - https://modernwisdom.locals.com/

    Get £250 discount on Eight Sleep products at https://eightsleep.com/modernwisdom (discount automatically applied)

    Get 83% discount & 3 months free from Surfshark VPN at https://surfshark.deals/MODERNWISDOM (use code MODERNWISDOM)

    Get over 37% discount on all products site-wide from MyProtein at https://bit.ly/proteinwisdom (use code: MODERNWISDOM)

    Extra Stuff:

    Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

    To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

    -

    Get in touch.

    Instagram: https://www.instagram.com/chriswillx

    Twitter: https://www.twitter.com/chriswillx

    YouTube: https://www.youtube.com/modernwisdompodcast

    Email: https://chriswillx.com/contact/ 

    1 hr 15 min

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