High on Life

Retatrutide - Top-Line Results from TRIUMPH 4

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In this quick update, I break down the newest Phase 3 data for retatrutide, Lilly’s investigational triple-agonist medication showing unprecedented results in obesity and knee osteoarthritis.

Highlights:

  • Up to 28.7% weight loss (~71 lbs) over 68 weeks
  • 75% reduction in knee pain and major improvements in physical function
  • Cardiometabolic benefits: lower triglycerides, non-HDL cholesterol, hsCRP, and blood pressure

    • We also cover

    • Common side effects and safety signals
    • Perceived excessive weight loss — and what this means for clinical practice in a new era of powerful medications
    • A reality check on Canadian availability (likely 3+ years away)
    • A strong warning about illegal online sales and the risks of buying unregulated products

      • A concise medical breakdown to help you stay informed and safe as the obesity-medicine landscape evolves.

      ...more
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      High on LifeBy Sasha High
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