Solving the Puzzle with Dr. Datis Kharrazian

In this episode, Dr. Liz Lipski covers what drives intestinal permeability, how LPS affects inflammation, autoimmunity, the brain, and the skin, which tests are most useful, and practical healing strategies like glutamine, zinc carnosine, quercetin, demulcents, and bone broth.

Enroll now in: Insights into Digestive Wellness, with Liz Lipski, PhD, FACN, CNS, IFMCP

A Kharrazian Institute Master Class at https://pages.kharrazianinstitute.com/lipski-digestive-wellness

Practitioners can start a free 7-day trial at kharrazianinstitute.com

TIMESTAMPS:

00:00 Understanding brush borders and zonulin

04:15 Causes of leaky gut

08:13 Causes of celiac disease

12:11 Understanding leaky gut and its tests

13:56 Testing lactulose and mannitol molecules

19:46 Gut health and soothing remedies

21:17 Podcast closing and resources

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Dr. Liz Lipski discusses how to choose the right elimination diet for each patient, why gut healing should be temporary, how resilient the microbiome really is, GLP-1s and Akkermansia, and which gut tests are actually useful.

Enroll now in: Insights into Digestive Wellness, with Liz Lipski, PhD, FACN, CNS, IFMCP

A Kharrazian Institute Master Class at https://pages.kharrazianinstitute.com/lipski-digestive-wellness

Practitioners can start a free 7-day trial at kharrazianinstitute.com

TIMESTAMPS:

0:00 Introduction & the early days of functional nutrition

4:30 Gaps in medical training & "when in doubt, start with the gut"

7:00 Choosing the right elimination diet

10:30 Carnivore, SIBO & resetting the microbiome

14:00 FODMAP reintroduction & the big three: dairy, eggs, gluten

16:00 Elimination diets, orthorexia & disordered eating

19:30 GLP-1s, Akkermansia & satiety

23:00 What gut testing is actually useful

26:00 Comparing stool tests & final thoughts

29:00 Closing

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Liz Lipski breaks down the three main types of digestive enzymes, how to test for pancreatic exocrine insufficiency using fecal elastase, and how to choose the right product for each patient. She walks through prescription options, full spectrum supplements, lipase-loaded formulas, and food-based sources, and explains why pancreatic insufficiency is so commonly missed because it presents exactly like IBS.

Enroll now in: Insights into Digestive Wellness, with Liz Lipski, PhD, FACN, CNS, IFMCP at https://pages.kharrazianinstitute.com/lipski-digestive-wellness

TIMESTAMPS:

00:00 Understanding Pancreatic Conditions

04:00 Testing for enzyme deficiency

07:13 Digestive enzymes and medical use

10:34 Protease enzymes and sensitivities

14:23 Digestive enzymes and their benefits

19:22 Enzyme naming and sensitivity options

23:15 Promoting resources for practitioners

24:13 Consult Your Healthcare Provider

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

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Ferritin is one of the most misunderstood markers on a blood test. A low-normal result doesn’t automatically mean iron deficiency, and an elevated result doesn’t necessarily mean iron overload. In this episode, Dr. Datis Kharrazian explains how ferritin reflects iron storage and inflammation, why unnecessary iron supplementation can create problems, and which tests offer clearer answers.

Interviewed by Elaine Marshall.

Want the most comprehensive functional medicine training? Start your seven-day free trial at kharrazianinstitute.com and access over 300 hours of clinical training with Dr. Kharrazian and leading functional medicine clinicians. 

If you're not a clinician, look for functional medicine patient courses at drknews.com.

TIMESTAMPS: 

00:00 Iron absorption and aging challenges

03:56 Misinterpreting Ferritin Levels

07:49 Understanding ferritin and hemochromatosis

13:07 Understanding health risks for MS patients

15:47 Iron storage depletion explained

17:25 Managing iron deficiency and inflammation

20:39 How the body processes iron

25:51 Learning from Christy Sutton's insights

28:09 Importance of Blood Chemistry Analysis

30:32 Promoting educational resources and courses

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

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Sunjya Schweig looks at where AI in clinical practice is headed over the next one to three years, from AI native EMRs and ambient scribing to fully integrated clinical copilots that surface real time insights and automate routine tasks. He outlines what practitioners who build fluency now will have over those who wait, why the skill advantage compounds over time, and how to stay current without drowning in information overload. 

Enroll now in: Clinical Applications of AI: A Competency-Based Masterclass for Integrative and Functional Medicine Practitioners, with Sunjya Schweig, MD at https://pages.kharrazianinstitute.com/schweig-ai-functional-medicine  

TIMESTAMPS: 

00:00 Discussing future AI developments

03:23 Automating patient intake with AI

09:09 AI streamlining healthcare decisions

10:57 Building expertise through micro-learning

16:45 AI fluency and customization in practice

18:53 Organizing and building with platforms

21:21 Closing and resources mention

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

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Dr. Sunjya Schweig explains how AI is changing day-to-day clinical work in functional medicine. He walks through his clinic's HIPAA-compliant Claude setup and the workflow he uses to compare answers across multiple LLMs. He also makes the case for practitioners to move beyond simply querying ChatGPT and build curated AI knowledge bases for specific chronic-health protocols, patient onboarding, and other recurring clinical tasks.

The conversation also covers the tensions of this transitional period. Patients now arrive at appointments with their own AI assistants, and insurance company bots are squaring off against practitioner automation. Dr. Schweig also discusses why the future of medicine may require more in-person connection, not less.

Sunjya K. Schweig, MD, is an expert in complex chronic illnesses that require rigorous investigation and management. He has studied, taught, and practiced integrative and functional medicine for over 25 years. He founded and leads the California Center for Functional Medicine (CCFM).

Timestamps:

0:00 Intro

0:27 Interview Begins

0:55 Dr. Schweig's Background

3:04 AI Hype vs. Doom

3:51 AI in Functional Medicine

6:13 Building Knowledge Bases

8:59 Patient-Facing AI

11:51 Quality of FM Info in LLMs

15:20 The Human Element

20:46 From Consumer to Producer

24:55 Mold Project Example

29:45 Marketing with AI

34:28 Insurance & AI Battles

36:35 Younger Generation & AI

37:05 Hiring AI Help

39:06 Closing Thoughts

41:21 Outro

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

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In this podcast Sunjya Schweig breaks down what AI agents actually are, how they differ from standard chat tools, and what they can realistically do in a clinical setting right now. He walks through the main platforms, real world use cases, and the safety protocols every practitioner needs to understand before giving an agent access to anything in their workflow. 

Enroll now in: Clinical Applications of AI: A Competency-Based Masterclass for Integrative and Functional Medicine Practitioners, with Sunjya Schweig, MD at https://pages.kharrazianinstitute.com/schweig-ai-functional-medicine 

TIMESTAMPS: 

00:00 AI personal agents and automation tools

06:25 Using cloud-based sandbox VMs

09:07 Agentic workflow and approvals

11:39 Using AI to find specialists

13:49 Understanding AI Agents and Use Cases

18:18 Resources for Healthcare Practitioners and Patients

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

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Seed oils have become a nutritional villain, but the real issue is more specific: oxidation. In this episode, Dr. Datis Kharrazian explains why heat and light can damage unstable oils, while cold-pressed options such as flaxseed, evening primrose, and black currant oil can provide essential fatty acids the body can’t make.

This conversation covers omega-3, omega-6, and omega-9 pathways, prostaglandins, insulin resistance, fatty liver, ketogenic diets, and brain health. You’ll also hear how to distinguish a beneficial oil from a rancid one, why olive oil and ghee are useful for cooking, and why blanket statements about all seed oils miss the biology.

Want to go deeper? Start your seven-day free trial at kharrazianinstitute.com and access over 300 hours of clinical training with Dr. Kharrazian and leading functional medicine clinicians. 

TIMESTAMPS: 

00:00 Discussion about seed oils and health

05:21 Identifying Essential Fatty Acid Imbalances

07:42 Benefits of different cooking oils

10:09 Health benefits of fatty acids

15:26 Managing Fatty Acid Intake

16:35 Understanding prostaglandins and inflammation

21:23 Healthy vs Unhealthy Keto Diets

23:19 Comparing fish oils and flaxseed

26:25 Benefits of ketogenic diet for brain

29:28 Consulting your healthcare provider

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AI can process enormous amounts of clinical information in seconds, but it has never seen a patient, built a clinical relationship, or developed clinical judgment through experience. This episode examines how AI can support treatment planning without replacing the clinician’s reasoning.

Enroll now in: Clinical Applications of AI: A Competency-Based Masterclass for Integrative and Functional Medicine Practitioners, with Sunjya Schweig, MD at https://pages.kharrazianinstitute.com/schweig-ai-functional-medicine 

TIMESTAMPS: 

00:00 Analyzing sleep data with custom GPT

03:05 Iterative refinement with AI

07:34 Creating a Fast Food Diet Plan

10:30 Evaluating AI in Clinical Diagnosis

16:23 AI's impact on clinical expertise

20:06 AI error vigilance in clinical notes

22:27 Discussing AI in clinical practice

25:26 Outro and resources for listeners

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

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In today’s Practitioner Spotlight, we speak with Dr. Edling, a seasoned chiropractor and functional medicine practitioner from the small town of Osceola, Wisconsin. With over 20 years of experience integrating functional medicine into a rural practice, he shares the unique challenges and rewards of serving a close-knit community with limited resources, from adapting care to meet patients’ financial constraints to the importance of ongoing learning and genuine relationships.

Interviewed by Elaine Marshall.

Want the most comprehensive functional medicine training? Start your seven-day free trial at kharrazianinstitute.com and access over 300 hours of clinical training with Dr. Kharrazian and leading functional medicine clinicians. 

If you're not a clinician, look for functional medicine patient courses at drknews.com.

TIMESTAMPS: 

00:00 Chiropractic and functional medicine journey

05:03 Mentoring young football coaches

06:37 Candidate selection and burnout discussion

10:03 Functional neurology focus and family

15:45 Discussing patient follow-through and rehab

18:32 Reflecting on Krause Experiences

21:01 Explaining the upstream health model

24:08 Family vacation and gluten challenge

26:59 Helping patients with financial struggles

32:43 Focus on personal health and fitness

35:07 Recovering from a major accident

39:27 Collaborating with Committed Clients

43:10 Encouragement for practitioners

45:33 Outro and program offerings

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.