In this episode, Dr. Yousef Elyaman, a leading functional medicine doctor, takes us into the pathogenesis of fatty liver disease, sharing his expertise on the underlying imbalances and physiological mechanisms that contribute to this complex condition.

We explore how functional medicine looks beyond traditional diagnostics and treatments, focusing instead on the root causes—whether that’s insulin resistance, genetics, diet, gut health, or hormone imbalances. Dr. Elyaman breaks down how comorbidities like obesity, diabetes, cardiovascular disease, and thyroid dysfunction are interconnected and why identifying these drivers is critical for lasting, meaningful change.

If you’re ready to connect cutting-edge science with practical strategies for chronic health challenges, join us for a masterclass in functional medicine with Dr. Yousef Elyaman. This episode is packed with insights you can apply immediately to improve patient outcomes or your own health journey.

Join us for an online livestream where you'll master the functional medicine strategies that reverse fatty liver. Register now at https://pages.kharrazianinstitute.com/elyaman-fatty-liver

For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/⁠

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For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/⁠

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For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/⁠

Timestamps:

00:00 Fatty Liver: Causes & Comorbidities

05:52 "Fructose, Insulin Resistance, and AGEs"

09:33 "Insulin's Role in Fat Regulation"

12:05 Triglycerides, LDL, and Heart Disease

15:41 Fatty Liver and Iron Overload

19:39 "SIBO and Digestive Health"

21:28 Gut Health and Fatty Liver Connection

25:32 "Functional Medicine Training & Resources"

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In this episode, Dr. Datis Kharrazian explores longevity medicine and the hallmarks of aging and disease. How do early signs of loss of resilience—like cognitive decline or changes in physical appearance—offer clues about our biological age? What can cutting-edge studies, such as the Dunedin Longitudinal Study, teach us about predicting poor aging trajectories and preventing chronic diseases like cardiovascular issues and cancer, before they silently take hold?

Dr. Kharrazian uncovers the mechanisms underlying tissue degeneration, explores why resilience is central to healthy aging, and explains how functional medicine clinicians can use biomarkers and in-depth assessments to help shift morbidity later in life. Whether you’re a healthcare practitioner, a nutrition enthusiast, or facing chronic health challenges, this episode bridges the gap between complex science and actionable steps you can implement right now.

Learn functional longevity strategies from Dr. Datis Kharrazian. Discover how to use personalized nutrition, diet, and lifestyle approaches to optimize healthspan. Enroll in the Longevity Mastery Program at: https://pages.kharrazianinstitute.com/longevity

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

In this episode, Dr. Kharrazian covers the physiological mechanisms that drive aging and how you can take proactive steps to slow disease progression and extend your healthspan.

Learn the foundational concepts of geroscience, the difference between anti-aging appearance medicine and true longevity medicine, and actionable clinical strategies for healthier longevity. You’ll learn why maintaining resiliency is key to a healthy, vibrant life, what laboratory markers and lifestyle interventions actually make a difference, and how to spot early signs of aging before they become disease. 

If you’re passionate about functional medicine, working with chronic patients, or simply want to invest in your own healthy future, this conversation is packed with the essentials you need.

Learn functional longevity strategies from Dr. Datis Kharrazian. Discover how to use personalized nutrition, diet, and lifestyle approaches to optimize healthspan. Enroll in the Longevity Mastery Program at: https://pages.kharrazianinstitute.com/longevity

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 "Exploring Aging, Health, and Longevity"

04:43 "Understanding Geroscience and Longevity"

09:46 "Hallmarks of Aging Explained"

13:36 "Addressing Chronic Inflammaging Challenges"

17:15 "Aging Pathophysiology in Practice"

18:41 "Restoring Physiological Resiliency"

24:11 Extending Human Lifespan Potential

25:47 "Secrets of Longevity: Jean Calment"

29:28 "Longer Lives, Declining Quality"

32:32 "Functional Medicine Resource Hub"

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

In this episode, Datis Kharrazian bridges complex science with practical strategies you can use right away, focusing on the fascinating concept of biological age versus chronological age.

You’ll learn why some people seem to age slower or faster than their years might suggest, and discover how factors like sleep, fasting, diet, and resilience are key to longevity and vibrant health. Datis Kharrazian dives into personalized clinical models, exploring mechanisms such as inflammation, cellular senescence, and genetic influences—and explains why resilience is the central feature in successful aging, healthspan, and overall wellness.

Whether you’re a healthcare professional looking to advance your functional medicine expertise or someone seeking effective strategies for chronic health challenges, this episode lays the groundwork for integrating functional medicine and geroscience into everyday practice. 

Learn functional longevity strategies from Dr. Datis Kharrazian. Discover how to use personalized nutrition, diet, and lifestyle approaches to optimize healthspan. Enroll in the Longevity Mastery Program at: https://pages.kharrazianinstitute.com/longevity

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 "Biological vs. Chronological Age"

04:25 "Inflammaging and Cellular Health Strategies"

08:49 "Resilience: Key to Longevity"

12:03 "Intermittent Fasting and Longevity"

13:00 "Longevity Research and Key Pathways"

19:25 "Genetics and Resilience in Aging"

21:03 "Resilience: Key to Healthy Aging"

23:23 "Enhancing Resiliency Through Geroscience"

27:39 "Inflammatory Resiliency and Intolerances"

30:40 "Geroscience: Aging and Resilience"

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

In this episode, we dive into the environmental and lifestyle factors that impact mood disorders like depression and anxiety. You'll learn how screen time, diet, sleep, and physical activity can set the stage for mental health—and why toxic exposures like pesticides, heavy metals, air pollution, mold, and electromagnetic fields can make things worse.

Drawing on the latest research and longitudinal studies, Dr. Datis Kharrazian breaks down the science behind mitochondrial dysfunction, neuroinflammation, and neurotransmitter imbalance. He shares practical advice for leveraging exercise, improving sleep quality, and minimizing toxic exposures, offering clear strategies that you can use for yourself or your patients. Whether you're a practitioner, a student, or someone seeking answers about mood and resilience, this episode bridges complex science and actionable solutions you can implement right away.

Enroll in the complete master class: Mood and Anxiety Disorders Clinical Strategies and Treatment Applications with Dr. Datis Kharrazian at: 

https://pages.kharrazianinstitute.com/mood-and-anxiety-disorders

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 Lifestyle Factors Linked to Depression

03:32 "Pesticides Linked to Mood Disorders"

08:59 "Heavy Metals Linked to Depression"

11:58 "Air Pollution's Link to Mental Health"

16:36 "Air Pollution's Impact on Brain"

17:35 "Mold Exposure and Neurocognitive Issues"

22:53 "Exercise Intensity Shapes Recovery"

27:13 "Exercise Boosts Mental Health Outcomes"

28:02 "Exercise Benefits for Mental Health"

31:56 "Sleep Consistency Supports Recovery"

34:21 "Subscribe and Share!"

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

In today’s episode, Dr. Datis Kharrazian takes a dive into the intricate relationship between blood sugar stability—what he calls dysglycemia—and mood disorders. You'll learn how rollercoaster blood sugar levels can disrupt neurochemistry, impact hormone balance, and even alter your brain’s stress response. Plus, Dr. Kharrazian explores why stabilizing blood sugar is critical before addressing neurotransmitter imbalances, and he explains real-world clinical signs. 

Enroll in the complete master class: Mood and Anxiety Disorders Clinical Strategies and Treatment Applications with Dr. Datis Kharrazian at: 

https://pages.kharrazianinstitute.com/mood-and-anxiety-disorders

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

In this episode, Dr. Kharrazian dives into the complex world of mood disorders, shining a light on why conditions like depression and anxiety have become such significant global health challenges. He questions the mainstream approach to treating mood disorders, revealing the limitations and biases present in antidepressant research and the pharmaceutical industry's influence on published data.

Dr. Kharrazian explores what’s truly happening in the brains of those suffering from chronic mood issues, moving beyond the conventional neurotransmitter model to focus on the importance of neuronal health and plasticity. He breaks down the latest findings on treatments like ketamine, the real risks and shortcomings of long-term antidepressant use, and the many underlying biological factors—from neuroinflammation to neurodegeneration—that practitioners need to consider.

Enroll in the complete master class: Mood and Anxiety Disorders Clinical Strategies and Treatment Applications with Dr. Datis Kharrazian at: 

https://pages.kharrazianinstitute.com/mood-and-anxiety-disorders

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 "Anxiety Meds: Benefits and Concerns"

03:27 Placebo Effect Outperforms Antidepressants

08:33 "Antidepressant Trial Reporting Bias"

10:09 "Long-Term Antidepressant Effectiveness Questioned"

14:43 Depression: Beyond Neurotransmitter Issues

18:06 Mood Disorders: Causes and Approaches

21:45 "Functional Medicine & Health Education"

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

In this episode, Dr. Kirk Gair dives into the clinical power of laser therapy—bridging the science behind this technology with its practical applications for chronic health issues, brain function, autoimmune conditions, and more.

You'll hear real case stories, from a doctor who saw dramatic improvements in brain activity after a stroke, to patients reversing years of debilitating symptoms, and even a few remarkable pet recoveries. 

Enroll in the complete master class: Enhanced Healing & Performance with High Energy Non-Thermal Laser Therapy with Dr. Kirk Gair at: 

https://pages.kharrazianinstitute.com/erchonia 

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 "Solving Health with Dr. Kirk Gair"

04:17 "Multi-Laser Healing Treatment"

07:30 "Pure Lasers for Optimal Therapy"

10:12 High-Energy Lasers and Biophotons

15:25 "Insulin Reduction & Carrageenan Risks"

18:57 Laser Therapy Helps Brain Injury

20:36 Chronic Illness and Resilience

23:14 Hopeful Path to Healing

29:25 "Laser Marketing for Doctors"

30:20 Functional Health & Nutrition Training

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

In today’s episode, Dr. Kirk Gair shares how a routine imaging procedure turned his family's life upside down, sending his wife into a severe health crisis that conventional medicine couldn’t solve. Faced with life-threatening symptoms and a string of specialists who could offer no answers, he turned to his old friend and functional medicine expert, Dr. Datis Kharrazian. Together, they uncovered an autoimmune thyroid reaction triggered by iodine, and charted a new path—combining advanced functional medicine protocols with cutting-edge low-level laser therapy.

You’ll learn how this approach not only reversed his wife's decline, but also explores the science and global potential of lasers in supporting chronic conditions, brain health, and autoimmune disease. 

Enroll in the complete master class: Enhanced Healing & Performance with High Energy Non-Thermal Laser Therapy with Dr. Kirk Gair at: 

https://pages.kharrazianinstitute.com/erchonia 

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 "ER Visit Misdiagnosed as Panic"

05:29 Healing Brain with Laser Therapy

06:27 "Laser Therapy for Inflammation Control"

12:31 Laser Therapy for Neurological Recovery

13:12 "Laser and Functional Medicine Success"

17:39 Childhood Crash Causes Lifelong Injuries

20:33 "Brian’s Transformation: A Waking Brain"

23:49 Autoimmunity Rise and Environmental Impact

28:08 "Solving the Puzzle Podcast"

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.

Most practitioners trust previous test results without question. But Dr. Steven Sandberg-Lewis reveals why SIBO breath tests, celiac testing, and pancreatic enzyme screening often produce false negatives—leading to years of misdiagnosis and treatment failure. With 46 years of clinical experience, Dr. Sandberg-Lewis explains the critical testing pitfalls that keep practitioners from accurately diagnosing their most complex GI patients.

Enroll in the complete master class: How to Think Like a Functional Gastroenterologist with Dr. Steven Sandberg-Lewis (6 hours) at pages.kharrazianinstitute.com/ssl-gastro⁠ to access over 45 years of refined clinical protocols and systematic approaches.

• For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/
• For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/
• For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/

00:00 Small Intestine Overgrowth Testing

06:29 "Celiac Diagnosis & Testing Insights"

07:42 Celiac, Gluten, and Endoscopy Insights

11:45 Pancreatic Exocrine Insufficiency Causes

18:13 "Functional Medicine Resources Overview"

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.

Hosted on Acast. See acast.com/privacy for more information.