The Dr. Hyman Show

This episode is brought to you by Rupa Health, BiOptimizers, Mitopure, and AquaTru.

⁣⁣NAD has been popping up everywhere, and for good reason. It’s a fundamental driver of our health and longevity, and we’re now learning how boosting NAD levels might offset and improve the effects of aging. 

On today’s episode, I’m excited to talk to Dr. Andrew Salzman all about NAD—how it is a key component involved in mitochondrial production, and is a critical substrate for several enzymes, including sirtuins, which play key roles in healthy aging, weight management, metabolic syndrome, and metabolism.

Dr. Salzman is a physician, inventor, professor, and biomedical entrepreneur. Dr. Salzman received his medical degree from Harvard University and has spent decades in drug discovery and development, raising over $165M in NIH grants for research. In addition to 50 patents, Dr. Salzman is credited with a breakthrough discovery in cellular DNA repair, which led to the world's first clinical application for successfully treating breast cancer caused by mutations in BRCA1 and BRCA2 genes. Millions of patients are benefiting from discoveries by Dr. Salzman in areas including mitochondrial health, gastrointestinal microbiota, damage caused by inflammation and oxidative stress to human cells and DNA, autoimmune disease, and cancer.

This episode is brought to you by Rupa Health, BiOptimizers, Mitopure, and AquaTru.

Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. You can check out a free, live demo with a Q&A or create an account a RupaHealth.com.

BiOptimizers is offering my listeners 10% off Sleep Breakthrough. If you buy two or more you’ll get a free bottle of Magnesium Breakthrough. This is a limited-time offer. Go to sleepbreakthrough.com/hyman and use the code hyman10. 

Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout.

Right now, my podcast listeners can access the AquaTru water filter for as low as $249. That’s $100 off the normal price. All you have to do is go to drhyman.com/filter, and you can get this special, exclusive price.

Here are more details from our interview (audio version / Apple Subscriber version):

Learn more about Wonderfeel Youngr NMN.

Hey podcast community, Dr. Mark here. My team and I are so excited to offer you a 7 Day Free trial of the Dr. Hyman+ subscription for Apple Podcast. For 7 days, you get access to all this and more entirely for free! It's so easy to sign up. Just go click the Try Free button on the Doctor’s Farmacy Podcast page in Apple Podcast. 

In this teaser episode, you’ll hear a preview of our monthly Ask Mark Anything episode.

Want to hear the full episode? Subscribe now. With your 7 day free trial to Apple Podcast, you’ll gain access to audio versions of:

- Ad-Free Doctor’s Farmacy Podcast episodes

- Exclusive monthly Functional Medicine Deep Dives

- Monthly Ask Mark Anything Episodes 

- Bonus audio content exclusive to Dr. Hyman+

Trying to decide if the Dr. Hyman+ subscription for Apple Podcast is right for you? Email my team at [email protected] with any questions you have.  

Please note, Dr. Hyman+ subscription for Apple Podcast does not include access to the Dr. Hyman+ site and only includes Dr. Hyman+ in audio content. 

Mentioned in this episode

ROOT by Hudson

This episode is brought to you by Rupa Health, AG1, Pique, and Joovv. 

While our body's detoxification systems are sophisticated and well functioning, they are not far enough evolved to protect us fully from the toxic burdens we encounter in our environment.

In today’s episode, I talk with Dave Asprey, Dr. Todd LePine, and Dhru Purohit about environmental contaminants that could be lurking behind your persistent health symptoms and why testing should be an integral part of our routine health exams as we age.

Dave Asprey is an entrepreneur, the “Father of Biohacking,” and the leading voice in the movement to take control of your own biology. He’s hosted over 1,000 episodes of The Human Upgrade podcast (formerly Bulletproof Radio) for more than a decade. He also hosts the world’s largest and longest-running biohacking conference. He’s a New York Times bestselling author of multiple books, creator of Danger Coffee and Bulletproof Coffee, and owner and CEO of Upgrade Labs, the world’s first Human Upgrade Center.

Dr. Todd LePine graduated from Dartmouth Medical School and is board certified in internal medicine, specializing in integrative Functional Medicine. He is an Institute for Functional Medicine Certified Practitioner. Prior to joining The UltraWellness Center, he worked as a physician at Canyon Ranch in Lenox, MA, for 10 years. His areas of interest include optimal aging, bio-detoxification, functional gastrointestinal health, systemic inflammation, autoimmune disorders, and the neurobiology of mood and cognitive disorders.

Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset.

This episode is brought to you by Rupa Health, Athletic Greens, Pique, and Joovv. 

Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.

Right now, Athletic Greens is offering 10 FREE travel packs of AG1 with your first purchase at drinkAG1.com/HYMAN.

For a limited time, get up to 12% off plus an exclusive gift on Pique’s Fasting Tea bundle at Piquelife.com/farmacyfasting.

For a limited time, you’ll get an exclusive discount on Joovv’s Generation 3.0 devices (some exclusions do apply). Just go to Joovv.com/farmacy and use the code FARMACY.

Full-length episodes of these interviews (and links to references mentioned) can be found here:

Dave Asprey

Dr. Todd LePine

Dhru Purohit

This episode is brought to you by Rupa Health and Levels.

What matters most in life is the quality of our experiences and the ability to be awake to what is real and true in our lives for both the difficult and the happy times. But that is harder than it sounds. More and more, we struggle with attention and focus.

In today’s episode of my series I’m calling Health Bites, I discuss why we are so easily distracted, my own journey into meditation, and the incredible health benefits of a regular meditation practice.

This episode is brought to you by Rupa Health and Levels.

Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.

Levels provides real-time feedback on how diet and lifestyle choices impact your metabolic health. Right now, Levels is offering an additional two free months of their annual membership. Learn more at levels.link/HYMAN.

Here are more details from our interview (audio version / Apple Subscriber version):

Mentioned in this episode

Ziva Meditation

This episode is brought to you by Cozy Earth, Rupa Health, Apollo, and Wonderfeel.

Over the years, it has become a widely held belief that cancer is predominately a genetic disease or simply the consequence of bad luck. An empowering evolution in cancer research, however, suggests we have far more control over our risk than previously thought. 

I’m excited to talk to Dr. Thomas Seyfried about the underlying causes of cancer and why addressing metabolic dysfunction is a very important and often overlooked area of its prevention and treatment. 

Dr. Thomas Seyfried is an American professor of biology, genetics, and biochemistry at Boston College. He received his Ph.D. from the University of Illinois Urbana-Champaign in 1976 and did his postdoctoral fellowship at the Yale University School of Medicine. Dr. Seyfried has over 150 peer-reviewed publications, and his research focuses primarily on the mechanisms driving cancer, epilepsy, and neurodegenerative diseases and calorie-restricted ketogenic diets in their prevention and treatment. He is the author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer and presently serves on the Nutrition & Metabolism, Neurochemical Research, Journal of Lipid Research, and ASN Neuro editorial boards.

This episode is brought to you by Cozy Earth, Rupa Health, Apollo, and Wonderfeel.

Get 40% off your Cozy Earth sheet at cozyearth.com and use code MARK40.

Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests. Check out a free, live demo with a Q&A or create an account at RupaHealth.com.

Apollo was designed by neuroscientists and physicians to tap into your body's natural rhythms to bring calm and focus and restore equilibrium to your nervous system. Check out the Apollo wearable and save $40 at apolloneuro.com/drhyman.

Wonderfeel Youngr NMN works by increasing your levels of NAD, a critical molecule our bodies produce that we literally need to survive. Feel the wonder of innovation at getwonderfeel.com.

Here are more details from our interview (audio version / Apple Subscriber version):

Learn more at tomseyfried.com and at the Foundation for Metabolic Cancer Therapies.

This episode is brought to you b Rupa University, Paleovalley, HigherDOSE, and Athletic Greens. 

There are many areas of life that we can dial in for optimal health and longevity. Three of those areas are what we eat, our quality of sleep, and our energy production. We eat pounds of food every single day that act as information for our cells and influence our DNA expression. When we sleep, our brain’s immune system (the glymphatic system) clears away damaged cells. And increasing our energy will not only help us feel better but will also support all the systems of the body to function better.

In today’s episode, I talk with Dhru Purohit in my Masterclass series about the Functional Medicine approach to food, improving our sleep, and powering up our bodies.

Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset.

This episode is brought to you by Rupa University, Paleovalley, HigherDOSE, and Athletic Greens. 

If you’re a healthcare provider who wants to learn more about Functional Medicine testing, you owe it to yourself to go check it out today. Go to rupauniversity.com to sign up for a free live class or a boot camp!

Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal.

Elevate your wellness game today by going to HigherDOSE.com. You can use promo code HYMAN at checkout to save 15% off site-wide or just go to HigherDOSE.com/hyman.

AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, Athletic Greens is offering 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman.

Full-length episodes of these interviews (and all referenced show notes) can be found here:

How to Use Food As Medicine

Daily Steps to Boost Energy and Never Be Tired Again

Why Sleep is More Important Than Diet—Optimize it Today

This episode is brought to you by BiOptimizers and Athletic Greens.

Taking care of yourself, practicing self-love and self-compassion, working on a growth mindset, building relationships and community, and having a sense of purpose are all crucial to living a fulfilling, long, healthy life. Your thoughts, feelings, and beliefs are all transmuted into biological signals that change your gene expression, impacting your immune function, hormones, microbiome, neurotransmitters, neuroplasticity, mitochondria, and more. Yet many of us tend to put self-care last on our list of to-dos (I certainly have for much of my life, to the detriment of my own health).

In today’s episode of my series I’m calling Health Bites, I share my strategies for prioritizing self-care for a healthy mind and spirit.

This episode is brought to you by BiOptimizers and Athletic Greens.

BiOptimizers is offering my listeners 10% off Sleep Breakthrough. If you buy two or more you’ll get a free bottle of Magnesium Breakthrough. This is a limited-time offer. Go to sleepbreakthrough.com/hyman and use the code hyman10.

AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, Athletic Greens is offering 10 FREE travel packs with your first purchase by visiting athleticgreens.com/hyman.

Here are more details from our interview (audio version / Apple Subscriber version):

This episode is brought to you by Rupa Health, Mitopure, Nordic Naturals, and Apollo.

We are a culture obsessed with happiness, except we’ve been going about it all wrong. Before I became a doctor, I actually studied Buddhism. I wanted to understand the root of human suffering, and through that, understand the way to create happiness. 

On today’s episode, I’m excited to talk to Dan Harris about the science of happiness, how to deal with the challenges of modern-day life, and how to create more happiness for ourselves and for those around us. 

Dan Harris is an author, podcaster, and entrepreneur. For 21 years, he worked as an anchor and correspondent for ABC News, hosting such shows as Nightline and the weekend editions of Good Morning America. Dan has reported from all over the planet, covering wars in Afghanistan and Iraq and producing investigative reports in Haiti, Cambodia, and the Amazon. After having a nationally televised panic attack on Good Morning America, Dan discovered meditation and then wrote the best-selling book 10% Happier as a way to encourage fellow skeptics to give the practice a shot. After that first book, Dan launched the Ten Percent Happier app, wrote a second book, and started the Ten Percent Happier podcast, where he interviews celebrities, entrepreneurs, authors, scientists, and meditation teachers about how to do life better.

This episode is brought to you by Rupa Health, Mitopure, Nordic Naturals, and Apollo.

Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests. Check out a free, live demo with a Q&A or create an account at RupaHealth.com.

Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout.

Shop Nordic Naturals omegas today at nordic.com and save 20% using code FARMACY.

Check out the Apollo wearable and save $40 by visiting apolloneuro.com/drhyman.

Here are more details from our interview (audio version / Apple Subscriber version):

The Dalai Lama's Guide to Happiness podcast series and video challenge

This episode is brought to you by Rupa Health, InsideTracker, and LMNT.

Compounds that have long been considered recreational drugs by conventional standards are finally being recognized through science as powerful tools for overcoming hard-to-treat health issues like PTSD, depression, addiction, and more. For the right person, psychedelics can provide a sense of peace and hope that helps heal their inner wounds and allows them to live with more freedom.

In today’s episode, I talk with Rick Doblin, Alberto Villoldo, and Wade Davis about the ancient healing mechanisms of plant medicine.

Rick Doblin, PhD, is the founder and executive director of the Multidisciplinary Association for Psychedelic Studies (MAPS). He received his doctorate in public policy from Harvard’s Kennedy School of Government. His professional goals are to help develop legal contexts for the beneficial uses of psychedelics and marijuana, primarily as prescription medicines but also for personal growth for otherwise healthy people, and eventually to become a legally licensed psychedelic therapist.

Medical anthropologist Alberto Villoldo, PhD, is an international bestselling author who has researched the shamanic healing practices of the Amazon and Andes for over 25 years. He is the founder of the Four Winds Society, an organization dedicated to the bridging of ancient shamanic traditions with modern medicine and psychology.

Wade Davis is a writer, photographer, and filmmaker. Explorer-in-Residence at the National Geographic Society from 2000 to 2013, he is currently Professor of Anthropology and the BC Leadership Chair in Cultures and Ecosystems at Risk at the University of British Columbia. He is the author of 23 books, including One River, The Wayfinders, and Into the Silence, and he was the winner of the 2012 Baillie Gifford Prize for Non-Fiction (formerly the Samuel Johnson Prize), the top nonfiction prize in the English language.

This episode is brought to you by Rupa Health, InsideTracker, and LMNT. 

Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.

InsideTracker is offering my community 20% off at insidetracker.com/drhyman.

LMNT is offering my listeners a free sample pack with any purchase. Get yours at DrinkLMNT.com/hyman today.

Full-length episodes of these interviews can be found here:

Rick Doblin

Alberto Villoldo

Wade Davis

This episode is brought to you by Rupa Health and InsideTracker.

We’ve become exposed to a greater number of environmental toxins than ever before. Environmental toxins can feed cancer, interfere with glucose and cholesterol metabolism, and induce insulin resistance and obesity through multiple mechanisms, including inflammation, oxidative stress, mitochondrial injury, altered thyroid metabolism, and impaired central appetite regulation. 

In today’s episode of my series I’m calling Health Bites, we’re talking about how environmental toxins impact our health, the top endocrine-disrupting toxins, and my strategies for reducing your exposure. I also share which foods you should be sure to buy organic.

This episode is brought to you by Rupa Health and InsideTracker.

Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.

InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman.

Here are more details from our interview (audio version / Apple Subscriber version):

Mentioned in this episode

EWG's Skin Deep Database

EWG's Guide to Healthy Cleaning

Thrive Market

Seatopia.fish

EWG’s 2023 Shopper’s Guide to Pesticides in Produce