Commune with Jeff Krasno

The Menopause Gut: How Hormones Shape Your Microbiome with Cynthia Thurlow

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What happens to your gut when estrogen declines?


In this episode, Jeff sits down with Cynthia Thurlow, nurse practitioner and author of The Menopause Gut, to explore the overlooked connection between hormones and digestive health.

  • How declining estradiol impacts the microbiome and increases inflammation
  • What is the estrobolome and estrogen processing in the gut
  • Why 80% of autoimmune conditions affect women
  • Sleep, stress, and their cascading effects on gut health
  • Practical protocols for nutrition, movement, and hormone optimization

    • This episode is for women navigating perimenopause and menopause, anyone curious about the gut-hormone connection, and those seeking science-backed strategies for midlife health.


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