Pro-metabolic Food Guide: https://mikefave.com/011526/FREE-CALCULATOR-GUIDE

Coaching: https://mikefave.com/011526/COACHING

0:00 Rising fasting glucose & A1C on low-carb/carnivore diets

3:30 Dr. Ben Bickman's theory on hemoglobin A1C and red blood cell lifespan

14:30 Bickman & Judy Cho discuss fasting glucose on carnivore diet

17:40 Ideal fasting blood glucose ranges (research data)

26:00 Bickman's protein sensitivity theory vs. gluconeogenesis explanation

35:30 The red blood cell lifespan theory examined

44:00 Research findings: RBC lifespan impact on A1C

49:00 Dr. Shawn Baker's lab results after 15 months carnivore (case study)

57:00 Judy Cho on A1C, red blood cells, and plant-based dieters

1:09:00 Blood glucose numbers on carnivore - what's problematic?

1:14:08 Judy Cho asks, "Why eat sugar to lower blood sugar?"

1:28:00 Dr. Cywes says "Excessive healing causes harm"

1:41:00 Insulin suppression and gluconeogenesis discussion

1:47:00 Clinical signs: Rising A1C, BUN, declining T3, testosterone issues

1:51:00 Closing thoughts - Understanding downsides of dietary approaches

Sources:

https://doi.org/10.1007/s00125-008-1246-y

https://doi.org/10.1016/S0140-6736(10)60484-9

https://doi.org/10.2337/dc12-1577

https://doi.org/10.3390/ijms17122093

https://doi.org/10.1152/ajpendo.00093.2009

https://doi.org/10.1007/s00394-015-1108-6

https://doi.org/10.3389/fphys.2017.00428

https://doi.org/10.1139/o76-082

https://doi.org/10.1038/onc.2009.160

https://doi.org/10.1210/jcem.85.5.6573

https://doi.org/10.3945/ajcn.2009.27834

https://doi.org/10.3390/jpm12101738

https://doi.org/10.1159/000342232

https://doi.org/10.1016/S0008-6363(96)00245-3

https://doi.org/10.1038/s41374-018-0038-3

https://doi.org/10.3978/j.issn.2072-1439.2015.10.04

Pro-Metabolic Food Guide & Calculator: https://mikefave.com/122625/FREE-CALCULATOR-GUIDE

Work With Me: https://mikefave.com/122625/COACHING

01:14 - “Energy and structure are interdependent at every level” - Ray Peat, PhD

03:22 - Why glucose is the optimal fuel

05:51 - Ray Peat’s logical framework vs low-carb assumptions

08:21 - Why bioenergetics explains dietary paradoxes

10:27 - Ray Peat Quote on Sugar & Oxidative metabolism

14:42 - Benefits of CO₂ 22:15 - Sugar’s support for oxidative metabolism

26:34: Ray Peat Clip on: Sugar and the thyroid: T4 → T3 conversion

42:15 - Dr. Ray Peat Clips on Sugar Lowering Stress

45:30 - What happens when your blood sugar drops

50:18 - What are the roles of the stress hormones?

53:57 - Transient rise in cortisol on low-carb?

59:17 - High protein and cortisol

1:01:32 - Is glucagon a stress hormone?

1:06:19 - Dr. Ray Peat on anti-inflammatory effects on insulin & sugar

01:19:02 - Why high insulin isn’t the goal

01:22:13 - Hypoglycemia is directly inflammatory

01:23:05 - Hypoglycemia increases clotting and vascular inflammation

01:28:14 - Dr. Ray Peat on the ideal sources of sugar

01:31:30 - Potassium depletion reduces insulin action

01:34:45 - Diuretics, ARBs, potassium retention, and insulin sensitivity

01:36:58 - Calcium’s anti-obesity and metabolic effects

01:39:08 - Why Dr Ray Peat paired dairy + fruit

01:42:00 - Ideal potassium, sodium, calcium, magnesium targets

01:43:23 - Why Ray Peat’s work gets misrepresented & honoring Ray Peat’s legacy

Ray Peat Sources

1. Ray Peat – Glycemia, starch, and sugar in context https://raypeat.com/articles/articles/glycemia.shtml

2. Ray Peat YouTube clips cited throughout:

https://www.youtube.com/watch?v=jQw1SJ3UFww

https://www.youtube.com/watch?v=buJpzZJoGsg

https://www.youtube.com/watch?v=bxnO0PzBdtQ

https://www.youtube.com/watch?v=pWEwav6x8Bg

Ray Peat Clips Channel: https://www.youtube.com/@RayPeatClips

Sources: In YouTube Description- https://youtu.be/1Cap9NmjLpM

Pro-Metabolic Food Guide & Calculator: https://mikefave.com/51225/FREE-CALCULATOR-GUIDE

Work With Me: https://mikefave.com/51225/COACHING

01:21 – Why low-carb and pro-metabolic camps disagree, and where they actually overlap

07:01 – The “sugar diet” trend and influencers adding carbs back in

08:53 – Reacting to Ben Bikman’s “fat burner vs sugar burner” claims

16:55 – How low-carb improves glucose markers without fixing the root metabolic problem

21:03 – Client case study: moderate-carb macros, DEXA results, and 5-month transformation

28:16 – Reacting to Ben Bickman & thyroid on keto

35:50 – How low-carb mimics starvation and alters hormones

43:05 – Reacting to Nick Norwitz & Dr. Ken Berry on the “Keto flu”

58:40 – Dr. Chaffee Straw mans Bioenergetic Approach with SAD

01:04:10 - Dr. Chaffee on Low thyroid & High Cortisol on Low- Carb Diets

01:13:58 – “Humans are lions”: critiquing the carnivore paradigm and its troubleshooting limits

01:25:49 – Dr. Ken Berry & Dr. Chaffee on Paul Saladino & fructose glycation

01:38:43 – Why low-carb “works” short term

01:41:18 – Dr. Ray Peat on carbs producing more CO₂ than fats

Sources:

Linked in YouTube Description ->

Build Your Pro Metabolic Diet: https://mikefave.com/92925-ENERGY

Work With Me: https://mikefave.com//92925-COACHING

Dr. Chris Knobbe's channel: https://www.youtube.com/@UCyRSoypSQDgCyYWmiWtOKgg

Time Stamps:

00:00 - Is saturated fat really the main culprit in heart disease?

02:07 - Heart disease was rare in the 19th century

07:15 - Sir William Osler and the first U.S. heart attack cases

18:07 - Coronary deaths explode from 1912 through the 1970s

25:16 - Seed oil consumption rises alongside heart disease

28:33 - Smoking decline, medical advances, but heart disease remains #1 killer

35:18 - How atherosclerosis develops and the role of oxidized LDL

46:43 - Linoleic acid makes LDL vulnerable to oxidation

53:38 - Why LDL alone cannot explain heart disease trends

58:22 - PUFA instability and lipid peroxidation risks 1

:05:16 - High cholesterol but zero heart disease: Chris's testimonial

1:11:01 - Processed foods, seed oils, and antioxidant depletion

1:17:45 - USDA data: dramatic rise in linoleic acid since 1909

1:24:23 - Where linoleic acid comes from: seed oils vs ancestral fats

1:28:03 - Saturated fat intake stayed flat while heart disease rose

1:30:04 - Ancel Keys, the lipid hypothesis, and dietary guidelines

1:37:29 - How PUFA lower cholesterol (SREBP and PPAR pathways)

1:44:39 - Cutting linoleic acid lowers oxidized metabolites in weeks

1:53:02 - Seed oils linked to obesity, diabetes, and metabolic dysfunction

1:56:14 - Final takeaways: avoid industrial seed oils, return to ancestral fats

Build Your Energy Based Diet: https://mikefave.com/ENERGY-82925

Work With Me: https://mikefave.com/COACHING-82925

Time Stamps:

00:00 - Prevalence of Obesity & Diabetes

7:38 - Sources of Chris's Data

14:20 - Is eating less the solution to the obesity epidemic?

22:09 - Does sugar consumption = obesity?

31:22 - What is to blame for obesity? Sugar or vegetable oil?

33:22 - Are carbohydrates responsible for obesity epidemic?

36:26 - Vegetable Oils = Obesity?

40:07 - Does sugar cause diabetes?

46:40 - Are carbohydrates & sugar responsible for diabetes?

52:33 - New research from 17 countries - Sugar Consumption

58:35 - New research from 17 countries - Carb Consumption

1:00:29 - 17 country study - Vegetable Oil Consumption

1:03:48 - Correlation vs. Causation, Randomized Control Trials etc.

1:22:25 - What is going on in France? 1:28:53 - New Research: Obesity

1:43:08 - How much vegetable oil a day increases obesity?

1:45:56 - New Research: Sugar, Carbs, Diabetes

1:48:56 - Hidden Sources of Seed Oils

1:50:57 - Do you need to stop eating carbs?

1:58:25 - Is there an ideal macronutrient ratio? 2:04:21 - Dietary Recommendations

Build Your Energy Based Diet: https://mikefave.com/energy-based-diet/

Work With Me: https://mikefave.com/coaching-program/

0:00 - Intro

1:06 - What Is The Randle Cycle

7:11 - Why Carb Oxidation Is Better Than Fat Oxidation 1

9:57 - Benefits of CO2

23:35 - Role of Insulin

32:28 - Steps to Reverse Insulin Resistance

37:10 - Optimal Amount of Fat Intake

43:28 - Best Fat Sources

46:28 - Importance of Vitamins and Minerals to Reverse Insulin Resistance

50:49 - What is the Upper Limit Fat Intake for a Healthy Individual

52:29 - Why Not to Eat as Little Fat as Possible

55:03 - Thoughts on Metabolic Flexibility

58:41 - Damaging Effects of Constantly High Levels of Insulin

1:04:44 - How to Test if You Are Oxidizing Carbs Well

1:10:24 - Tracking Calories Debate

Disclaimer: This video is for informational purposes only and does not constitute medical, nursing, or healthcare advice. It does not establish a doctor-patient relationship. The use of this information is at the user’s own risk and is not a substitute for professional medical advice, diagnosis, or treatment. Users should consult a qualified healthcare provider before making any dietary, lifestyle, or medical changes. The views expressed are for educational discussion only.

Build Your Energy Based Diet: https://mikefave.com/energy-based-diet/

Work With Me: https://mikefave.com/coaching-program/

Grab The Cronometer Sugar Diet Templates: https://welcome.mikefave.com/sugar-diet-templates

How To Set Up a Sugar Diet Without Ruining Your Health: https://youtu.be/lv8au4X5Gb8?si=pN6LGxHUt_5Rmn-i

🔹Time Stamps:

0:00 - Intro

3:01 - How People Are Losing Weight On The Sugar Diet

6:36 - What is FGF21 & How It Works

12:15 - Is FGF21 A Stress Hormone?

15:35 - Is FGF21 Increasing Net ATP Production?

21:35 - Uncoupling Effects From Thyroid Function vs. FGF21

23:45 - FGF21 Resistance 30:55 - Sugar Increase Insulin Sensitivity

35:36 - Is Low Fat, Low Protein, High Sugar The Fastest Way To Reverse Insulin Resistance

43:21 - The Sugar Diet Spectrum Pros & Cons 59:33 - Will You Gain Weight On A Purely Refined Sugar Diet?

1:00:53 - Will High Carbohydrate Intake Protect You Muscle Loss On The Sugar Diet?

1:05:45 - Lowest Amount Of Daily Protein Intake To Optimize Insulin Sensitivity & Still Preserve Muscle Mass

1:09:10 - Low Carb Diets & Insulin Resistance + Shawn Baker's Labs

1:13:52 - How To Know If You Should Do The Sugar Diet

🔹 Disclaimer: This video is for informational purposes only and does not constitute medical, nursing, or healthcare advice, nor does it establish a doctor-patient relationship. The use of this information is at the user’s own risk and is not a substitute for professional medical advice, diagnosis, or treatment. Users should not delay seeking medical advice and should consult a qualified healthcare provider before making any dietary, lifestyle, or medical changes. The views expressed are for educational discussion and do not constitute medical treatment or diagnosis.

Mike Fave and Ethan Wright discuss 7 key benefits of dairy outlined in Dr. Ray Peat's article, ”Milk in context: allergies, ecology, and some myths.” Spotify: Apple:

✅ Download The Nutrition Blueprint → https://mikefave.com/the-nutrition-blueprint/

✅ Work With Me → https://mikefave.com/work-with-me/

🔹 Where to Find Me:

✅ Website: https://mikefave.com/

✅ Twitter: https://x.com/MikeFaveScience/

✅ Instagram: / mikefavescience

✅ YouTube: / @mikefavescience

🔹 Timestamps:

0:00 - Intro

4:01 - Understanding Dr. Ray Peat's Work

8:05 - Calcium & Parathyroid Hormone

17:21 - Calcium's Anti-Obesity Effect

20:34 - Quality of Dairy Proteins Vs. Other Types of Protein

28:56 - Low PUFA Content of Dairy

32:31 - Carbohydrates in Milk Lower Cortisol

40:06 - Low Iron Content of Dairy

45:11 - Cows Filter Out Toxins

47:58 - Additives in Dairy

52:14 - The Diary Spectrum

54:49 - Most Tolerated Sources of Dairy

1:01:25 - Key Takeaways

🔹 Sources: https://pubmed.ncbi.nlm.nih.gov/24731656/ https://pubmed.ncbi.nlm.nih.gov/32835617/

https://pubmed.ncbi.nlm.nih.gov/36615866/

https://pubmed.ncbi.nlm.nih.gov/24482589/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4153072/

https://pubmed.ncbi.nlm.nih.gov/24951650/

https://raypeat.com/articles/articles/milk.shtml

🔹 Disclaimer: This video is for informational purposes only and does not constitute medical, nursing, or healthcare advice, nor does it establish a doctor-patient relationship. The use of this information is at the user’s own risk and is not a substitute for professional medical advice, diagnosis, or treatment. Users should not delay seeking medical advice and should consult a qualified healthcare provider before making any dietary, lifestyle, or medical changes. The views expressed are for educational discussion and do not constitute medical treatment or diagnosis.

In this episode of The Mike Fave Podcast, we discuss 3 reasons why you could be struggling to tolerate dairy. Many people come to a pro-metabolic style of eating and use dairy as a centerpiece of the diet. For some people this works great and others experience a variety symptoms. In this episode we cover the symptoms you could be experiencing from different types of dairy and the strategies you can use to overcome them.

✅ Download The Nutrition Blueprint → https://mikefave.com/the-nutrition-blueprint/

✅ Work With Me → https://mikefave.com/work-with-me/

🔹 Where to Find Me:

✅ Website: https://mikefave.com/

✅ Twitter: https://x.com/MikeFaveScience/

✅ Instagram: / mikefavescience

✅ YouTube: / @mikefavescience

🔹 Timestamps:

0:00 - Intro

2:00 - Mike's Experience With Dairy

4:58 - 3 Reasons Why You May Not Tolerate Dairy

6:08 - What Percent Of Mike's Clients Start With Dairy In The Diet

12:16 - Lactose Intolerance

20:38 - Can You Have Dairy If Your Lactose Intolerant?

25:43 - Lactose Free Dairy Options

27:00 - Can Taking Antibiotics Help You Tolerate Dairy?

31:00 - Symptoms of Casein Intolerance

33:33 - Mechanism Behind Casein Intolerance

37:54 - Solutions For Casein Intolerance

43:11 - Hormonal Problems With Dairy

54:04 - Changes To Modern Day Cows

58:17 - Solutions If You Have Hormonal Problems With Dairy

1:02:10 - Key Takeaways & Solutions

🔹 Sources:

http://www.rcsb.org/pdb/explore/explore.do?structureId=1jyn

https://pubmed.ncbi.nlm.nih.gov/33946892/

https://pubmed.ncbi.nlm.nih.gov/31505870/

https://pubmed.ncbi.nlm.nih.gov/19496976/

In this episode of The Mike Fave Podcast, we are joined by Dr. Chris Knobbe—physician, researcher, and author of The Ancestral Diet Revolution—to explore one of the most important topics in health today: seed oils.

We use graphs from "The Ancestral Diet Revolution" to illustrate seed oils rise in the modern food supply, the mechanisms by which they contribute to metabolic dysfunction, and the real strategies I use with my clients to repair the damage.

✅ Download The Nutrition Blueprint → https://mikefave.com/the-nutrition-blueprint/

✅ Work With Me → https://mikefave.com/work-with-me/

🔹 Where to Find Me:

✅ Website: https://mikefave.com/

✅ Twitter: https://x.com/MikeFaveScience/

✅ Instagram: / @mikefavescience

✅ YouTube: / @mikefavescience

🔹 Timestamps:

0:00 - Intro to Chris's Background

3:04 - What Is Driving Chronic Diseases?

10:53 - Saturated Fat & Vegetable Oil Vs. Heart Disease Deaths

16:05 - Obesity & Vegetable

24:45 - Sugar & Vegetable Vs. Debates

29:44 - Sugar & Vegetable Oil Vs. Cancer

41:15 - Will Removing Sugar From Diet Fix Your Blood Sugar

43:53 - Linoleic Acid & Cancer

47:29 - Why Retrospective Observational Epidemiological Studies Are Important

53:38 - The Problem Only Relying On Human Randomized Control Trials

57:04 - The Mechanism Behind PUFA Being Harmful

🔹 Sources:

Weston Andrew Price. Nutrition and Physical Degeneration. Lemon Grove, Ca Price-Pottenger, 2016.

Knobbe, Chris A, and Suzanne J Alexander. The Ancestral Diet Revolution. 14 May 2023.

(full list on website)