The Human Upgrade: Biohacking for Longevity & Performance

This Nobel Prize Discovery Reverses Aging In 72 Hours : 1432


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Is aging an inevitable decline, or just a "repair backlog" your body hasn't cleared yet?. In this episode, Dave breaks down the 2016 Nobel Prize-winning science of autophagy—the body's internal recycling system discovered by Dr. Yoshinori Ohsumi.


Most people are stuck in a state of "biological debt," where cellular junk piles up like trash in a factory, leading to brain fog, fatigue, and chronic inflammation. Standard 16-hour fasts aren't enough to reach the deep-cleaning phase. You will learn the exact 3-day protocol to trigger a "Deep Reset," where ketones peak, inflammation falls, and stem cells wake up to rebuild your immune system from scratch.


Join my FREE Fasting Challenge: https://daveasprey.com/fast-this-way-challenge/


Timestamps:

00:00 - The Anti-Aging Switch

01:30 - Chronological vs. Biological Age

02:32 - How Aging Works at the Cellular Level

04:58 - 43 Ways to Upgrade Your Mitochondria

07:37 - What Is Autophagy

09:17 - The Stages of Fasting

10:46 - What Happens During a 3-Day Fast

13:04 - How to Fast Correctly

14:42 - Breaking the Fast

15:58 - The Power of Subtraction


Thank you to our sponsors!

-KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off

-Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/


Connect with Dave Asprey!


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The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/


Danger Coffee: https://dangercoffee.com/DAVE15

Dave Asprey’s BEYOND Conference: https://beyondconference.com/

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15

Upgrade Labs: https://upgradelabs.com

40 Years of Zen: https://40yearsofzen.com

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The Human Upgrade: Biohacking for Longevity & PerformanceBy Dave Asprey

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