Today, we welcome back a guest from the early days of this podcast, fellow former vegan and esteemed researcher and scientist, Chris Masterjohn. Chris Masterjohn earned his PhD in Nutritional Sciences from the University of Connecticut, and has worked as a postdoctoral research associate and Assistant Professor of Health and Nutrition Sciences. 

In 2016, he transitioned to entrepreneurship. These days, Chris conducts independent research, consults, develops information products, and creates free content to help people improve their health. 

Chris is dedicated to sharing practical principles from complex science, and to the pursuit of truth and continuous learning. He's a biohacker from before the word “biohacking” came to be, appearing on episode 16 of this podcast when I was just getting that movement started, because he not only pays attention to how stuff works in the world and academic research, but he hacks his own body. I've always liked the way he thinks mechanistically about biology, nutrients, and what to eat. 

In this conversation, we talk about how to recover from veganism and reverse the effects of oxalates, highlighting the long term health impacts of the vegan diet. His own self experimentation lately is of particular interest to me as he’s been exploring the intersection of genetics and mitochondrial health to heal niche health conditions and even quell extreme fears or stressors.

We also talk about the link between energy metabolism and psychological trauma, chronic pain and oxalate overload, and even explore the potential dangers of methylene blue from his latest 58 page research paper breaking down the importance of correct dosing. 

If you’re a true biohacker, you’re going to love this deep dive into how minerals and metabolism play a huge role in our biology.

(03:47) Genetic Optimization: A New Approach to Healing Chronic Pain & Disease

• How his perspective on nutrition has changed since our first episode

• The extreme effects veganism had on his health

• Using genetics research to find solutions to rare health issues

• The role of AI in diagnosing health conditions—now and in the future

• Focusing on mitochondria as the root cause to heal health issues 

• Access his program: chrismasterjohnphd.com

• What will reverse the anti fertility trend?

• The psychological rewiring required to heal chronic disease states 

• Lowering your stress response with GABA and hierarchical exposure therapy

• How energy metabolism and psychological trauma symptoms are related

(32:08) Recovering from Veganism & Oxalate Overload

• Can you do veganism well?

• Addressing the impact of plant toxins and oxalates

• The link between chronic pain and oxalate overload

• How to reverse the effects of oxalates

• The use of biotin to clear oxalates and dosing suggestions

• Read: Toxic Superfoods by Sally Norton 

• Oxalate dumping symptoms explained 

• Advice for recovering vegans

• Read: Le Chatelier's principle

• Viome: viome.com

(01:04:09) Methylene Blue: Potential Dangers & Dosage Recommendations

• The dangers of combining methylene blue with ayahuasca and psychedelics

• Research conclusions on methylene blue dosing

• How methylene blue can impact people with Alzheimer’s

• Side effects of combining methylene blue with SSRIs

• Using methylene blue to help allergy sufferers

• ED as a side effect of methylene blue

Resources

Dave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books 

Website: chrismasterjohnphd.com

Facebook: facebook.com/chrismasterjohn

X: twitter.com/ChrisMasterjohn

Rumble: rumble.com/user/chrismasterjohn

YouTube: youtube.com/user/chrismasterjohn

Gab: gab.com/chrismasterjohn

Telegram: t.me/chrismasterjohnphd

GETTR: gettr.com/user/chrismasterjohn

Podcast: Everything You Need To Know About Saturated Fat & Cholesterol with Chris Masterjohn #16

Podcast: Nicotine, the Perfect Psychotropic? Dr. Paul Newhouse # 494

The Human Upgrade is produced by Crate Media.

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