The Human Upgrade with Dave Asprey

Upgrade Your Metabolic System with the Right Foods – Dr. Robert Lustig – Best of 2021


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IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™…

 … Dr. Robert Lustig’s knowledge about the metabolic system landed with listeners in a big way.

He’s a New York Times bestselling author of several books about the problems caused by sugar, processed food and the health conditions of obesity. 

In his latest book “Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine,” he focuses on how real food can reverse chronic disease and promote longevity. He also challenges the current healthcare paradigm and the influence of Big Food, Big Pharma, and Big Government. 

“I wrote Metabolical to basically explain what is healthy,” Dr. Lustig says. “And based on the empiric data, based on the science, based on the pathologies that I describe in the book that belie chronic disease, I distilled all of the information down to six words – two precepts, six words: ‘Protect the liver, feed the gut.’”

These are the eight cell pathologies that underlie all chronic disease, according to Dr. Lustig:

  • glycation
  • oxidative stress
  • mitochondrial dysfunction
  • insulin resistance
  • membrane instability
  • inflammation
  • epigenetics
  • autophagy


"[When] you look at the entire molecular mechanism of every single one of those eight subcellular pathologies, none of them have a medicine," he says. "None of them are druggable. They're all foodable." 

His book also documents how processed food has impacted human health, the economy, and the environment over the past 50 years. 

“It’s not about obesity, it never was,” Dr. Lustig says. “The key to the kingdom is that it is not about obesity, it is about metabolic dysfunction and anyone can get it, and that’s what makes it a public health crisis, because obesity is a result of the problem, not the cause.”

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