Question: Why Would Vitamin C cause muscle pain, joint pain, and brain fog? Short Answer: Acutely, vitamin C would likely cause these effects by generating oxalate, which could cause crystals that lead to muscle and joint pain, and could cut energy metabolism in half, leading to brain fog. This vulnerability could result from deficiencies of any of the B vitamins, any of the electrolytes, or of iron, copper, or sulfur; from diabetes, low adrenals, or hypothyroidism; or from any of the hundreds of genetic defects in energy metabolism, only one of which is glucose 6-phosphate dehydrogenase deficiency; or any one of a huge number of toxins that impair energy metabolism. Chronically, vitamin C may increase the harms of iron overload or contribute to copper deficiency. The main ways to manage these latter issues are to take vitamin C away from meals, to maintain good copper status through proper dietary intake, and to treat iron overload with phlebotomy.

This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:

https://chrismasterjohnphd.substack.com/p/questions-on-nac-biofilms-vitamin

In that batch of free episodes you will also find the answer to this question:

• Can NAC hurt your gut health?

• How to Find the Root Cause of Autoimmunity?

If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up:

https://chrismasterjohnphd.substack.com/qanda

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This snippet is from the May 13, 2023 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what's included:

• GLA to lower hydroxyhaemopyrrolin-2-one?

• When would I use the StrateGene and Genova Methylation Panel for nutritional testing?

• Energy metabolism as a root cause of gut issues?

• Nutrition for skin healing?

• Nutrition for hypnic jerks?

• Suggestions for snoring or sleep apnea?

• Nutrition to protect against restaurant meals?

• What is the cause of crusty eyes in the morning?

• What causes brain fog?

• How much oxalate should one eat each day?

• Should I be concerned about low alkaline phosphatase?

• What nutrients give tall children to short parents?

• Energy metabolism impairment mimicking Wilson's disease.

• Can taking digestive enzymes reduce our own production?

• Rapid-fire response to non-winners from the question contest.

Here's a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-may

Access the show notes, transcript, and comments here.

Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.