October 03, 2025

Does Melatonin Help Ease Migraines?

8 minutes

More than 1 billion people worldwide and 12% of Americans live with migraines, a disabling neurological condition that disrupts sleep, work, and daily life
Melatonin does more than regulate sleep; it also shields your brain at a cellular level by neutralizing damaging free radicals and reducing inflammation linked to migraines
Research shows melatonin reduces headache frequency by 51%, intensity by 53%, and duration by 46%, offering a powerful natural alternative to standard pharmaceutical drugs
Adults with episodic migraines taking 3 mg of melatonin before bed experienced the strongest improvements, often cutting their migraine frequency by half or more
Melatonin's safety profile is superior to common drugs like amitriptyline, with fewer and milder side effects, making it a well-tolerated option for migraine prevention

...more

By Dr. Mercola

4.6

14871,487 ratings

October 03, 2025

8 minutes

More than 1 billion people worldwide and 12% of Americans live with migraines, a disabling neurological condition that disrupts sleep, work, and daily life
Melatonin does more than regulate sleep; it also shields your brain at a cellular level by neutralizing damaging free radicals and reducing inflammation linked to migraines
Research shows melatonin reduces headache frequency by 51%, intensity by 53%, and duration by 46%, offering a powerful natural alternative to standard pharmaceutical drugs
Adults with episodic migraines taking 3 mg of melatonin before bed experienced the strongest improvements, often cutting their migraine frequency by half or more
Melatonin's safety profile is superior to common drugs like amitriptyline, with fewer and milder side effects, making it a well-tolerated option for migraine prevention

...more