Dr. Dale Bredesen explains how inflammation, toxins, and metabolic dysfunction drive Alzheimer’s—and how a systems approach may help reverse cognitive decline.

Dr. Dale Bredesen discusses a new systems-based understanding of Alzheimer’s disease, explaining how cognitive decline emerges from a network imbalance in the brain. In conversation with Dr. Richard Horowitz, he explores how mitochondrial dysfunction, inflammation, infections, toxins, and metabolic issues contribute to neurodegeneration—and why addressing multiple root causes simultaneously may help improve cognitive health.

Dr. Dale Bredesen is a neuroscientist and internationally recognized expert in neurodegenerative diseases, including Alzheimer’s disease. A graduate of Caltech and Duke University School of Medicine, he has published more than 200 scientific papers on the mechanisms of neurodegeneration. His work focuses on identifying the root causes of cognitive decline and developing comprehensive, personalized strategies aimed at preventing and reversing Alzheimer’s disease.

Dr. Terry Wahls shares how diet, lifestyle, and the Wahls Protocol may help reduce neuroinflammation and support recovery from autoimmune conditions.

Dr. Terry Wahls shares her personal journey from relying on a wheelchair for years due to multiple sclerosis to regaining mobility through targeted diet and lifestyle changes. In this conversation with Dr. Darin Ingels, she explains the Wahls Protocol, the role of mitochondrial health, the gut microbiome, and how nutrition, sleep, and stress management can influence neuroinflammation and recovery in autoimmune and chronic illness.

Dr. Terry Wahls is an Institute for Functional Medicine Certified Practitioner and a board-certified internal medicine physician. She also conducts clinical trials testing the efficacy of diet and lifestyle in the setting of multiple sclerosis. In 2018, she was awarded the Institute for Functional Medicine’s Linus Pauling Award for her contributions to research, clinical care, and patient advocacy. In addition, Dr. Wahls has secondary progressive multiple sclerosis, which confined her to a tilt-recline wheelchair for four years. Dr. Wahls restored her health using a diet and lifestyle program she designed specifically for her brain and now pedals her bike to work each day. She is the author of The Wahls Protocol: How I Beat Progressive MS Using Paleo Principles and Functional Medicine, The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles (paperback), and the cookbook The Wahls Protocol Cooking for Life: The Revolutionary Modern Paleo Plan to Treat All Chronic Autoimmune Conditions. Learn more about the current study, Efficacy of Diet on Quality of Life in Multiple Sclerosis, here.

Dr. Anshul Gupta explains the Hashimoto’s–MS connection, root causes, testing strategies, and lifestyle steps to reduce autoimmune inflammation.

Dr. Anshul Gupta explores the powerful connection between Hashimoto’s thyroid disease and multiple sclerosis. He explains how thyroid hormone affects remyelination, why comprehensive thyroid testing is essential, and how autoimmune diseases often cluster together. The conversation covers root causes—from food sensitivities and nutrient deficiencies to stress, infections, and toxins—along with practical lifestyle steps to reduce inflammation and support thyroid and mitochondrial health.

Dr. Anshul Gupta is a best-selling author, speaker, researcher, and world expert in Hashimoto’s disease. He educates people worldwide on reversing Hashimoto’s disease.

He is a Board-Certified Family Medicine Physician, with advanced certification in Functional Medicine, Peptide therapy, and also Fellowship trained in Integrative Medicine.

He has worked at the prestigious Cleveland Clinic Department of Functional Medicine alongside Dr. Mark Hyman. He has helped thousands of patients to reverse their health issues by using the concepts of functional medicine.

His dedication towards his patients was recognized when he was awarded Reader's Choice, Best Doctor in the Northern Neck Area.

He is now on a mission to help 1 million people reverse their health conditions. To achieve this mission, he has written a best-selling book called Reversing Hashimoto’s. He has also started a virtual functional medicine practice, a blog, and a YouTube channel so he can reach people from all over the world. And recently, he also hosted the Reversing Hashimoto’s summit by DrTalks.

Megan Weigel, DNP, explains how lifestyle medicine, sleep, stress, and energy healing complement disease-modifying therapies for MS.

Megan Weigel, DNP, ARNP-c, MSCN, discusses how integrative lifestyle medicine supports patients with multiple sclerosis alongside disease-modifying therapies. She shares real-world success stories of patients who embraced nutrition changes, stress reduction, better sleep, and mindfulness practices. The conversation explores alcohol moderation, cognitive behavioral therapy for insomnia, and energy medicine approaches that help patients build resilience and improve quality of life with MS.

Dr. Megan Weigel is a nurse practitioner specializing in neurological care in Jacksonville Beach, FL. She has been a Multiple Sclerosis (MS) certified nurse since 2005, and an NP for over 20 years. She is also a board-certified Advanced Practice Holistic Nurse. She earned her doctorate of Nursing Practice from the University of Florida, where her research emphasis was on preventive healthcare. She completed a fellowship in Integrative Medicine at the University of Arizona in the Fall of 2018, which complements her practice focus on wellness and holistic care. She is the past-president of the International Organization of MS Nurses and the co-founder of oMS Yoga. This non-profit organization brings free yoga classes to people living with MS (www.omsyoga.org). Her bestselling book, Monday Mantras with Megan, offers an approachable mindfulness journey and is available on Amazon.

Dr. Elisa Song explains why childhood autoimmunity is rising and how gut health, mitochondria, and mindset shape kids’ immune resilience.

Dr. Elisa Song discusses the alarming rise in childhood autoimmunity and explains how the microbiome, mitochondrial health, and mindset shape immune development. She breaks down the impact of antibiotics, processed foods, emulsifiers, screen time, stress, and medication use on children’s health. The episode offers empowering, practical tools parents can use to support gut balance, immune resilience, and long-term wellness.

Elisa Song, MD, is an integrative pediatrician, pediatric functional medicine expert, and mom to 2 thriving children. In her integrative pediatric practice, Whole Family Wellness (www.wholefamilywellness.org), she’s helped 1000s of kids get to the root causes of their health concerns and helped their parents understand how to help their children thrive – body, mind, and spirit – by integrating conventional pediatrics with functional medicine, homeopathy, acupuncture, herbal medicine, and essential oils. Dr. Song created Healthy Kids Happy Kids (www.healthykidshappykids.com) as an online holistic pediatric resource to help practitioners and parents bridge the gap between conventional and integrative pediatrics with an evidence-based, pediatrician-backed approach.

Dr. Cassie Smith shares her personal journey from Graves’ disease to Hashimoto’s and how she reversed her condition by focusing on gut health, inflammation, sleep, stress reduction, and whole-food nutrition. She explains the gut-thyroid connection, microbiome imbalances like SIBO, and why consistency—not extremes—is key to healing. This episode offers practical tools to restore balance and take ownership of your thyroid health.

Dr. Cassie Smith is a dual board-certified physician by the ABIM in Endocrinology, Diabetes, Metabolism, and Internal Medicine who founded Modern Endocrine after years of struggling with an autoimmune thyroid disease herself. She is passionate about functional and holistic medicine, along with determining the root causes of disease, because of her personal medical journey with Graves Disease and Hashimoto’s for years without answers.

At Modern Endocrine, Dr. Smith and her team are dedicated to providing comprehensive and personalized endocrinology care for conditions such as insulin resistance, weight management, thyroid disorders, and hormonal imbalances. Her practice focuses on a 10-step system to repair cellular damage, restore gut health, enhance metabolism, balance hormones, and promote overall wellness through a holistic and preventative approach. Dr. Smith believes in the power of personalized medicine to provide the most effective and appropriate care for each individual patient. Therefore, Modern Endocrine tailors treatments to each individual’s unique needs by thoroughly understanding each patient’s medical history, lifestyle, and health goals. This information is used along with extensive lab, gut, and genetic testing to customize treatment plans and teach lifestyle modifications. As an expert endocrinologist, she can help any patient struggling with overwhelm make changes to rebalance and align their health.

Dr. Miles Nichols reveals how hidden infections, B12 antibodies, and chronic inflammation drive thyroid fatigue—and how to address root causes.

Dr. Miles Nichols shares his personal journey through chronic fatigue and subclinical thyroid dysfunction, explaining how hidden infections, stomach autoimmunity, B12 issues, mold exposure, and cumulative stress load can drive thyroid symptoms. He breaks down molecular mimicry, autoimmune triggers, and practical resilience-building strategies—from foundational lifestyle habits to advanced functional testing.

Dr. Miles Nichols is a functional medicine doctor specializing in Lyme, mold illness, gut, thyroid, and autoimmunity. After Dr. Miles personally struggled with chronic fatigue in his early 20’s, Dr. Miles dedicated himself to figuring out the root causes. He suffered from and recovered from thyroid dysfunction, autoimmunity, a gut infection, Lyme co-infections, and mold illness.

Dr. Miles has authored two books. He founded the Medicine with Heart functional medicine clinic in Colorado, as well as the Medicine with Heart Institute that trains other doctors in functional medicine. Dr. Miles has been a featured speaker at national conferences, professional associations, podcasts, and summits.

Dr. Todd Watts explains how parasites, toxins, and terrain imbalance drive chronic gut issues—and how to address the true root cause.

Dr. Todd Watts shares his personal journey through Lyme, chronic fatigue, and parasite-related illness, and explains how terrain imbalance—not just infections—drives persistent gut dysfunction. He breaks down the role of toxins, parasites, immune suppression, and drainage pathways in chronic illness, and outlines why true healing requires addressing toxic burden, supporting elimination, and restoring the body’s natural resilience.

Dr. Todd A. Watts is a national board-certified Chiropractic Physician in Idaho and a Functional Wellness Practitioner. Many know him as the “Parasite Guy”, but he also has extensive knowledge in Functional Blood Chemistry, Biochemistry, and in helping those with chronic illness overcome their struggles to restore their health. He is also the cofounder of Microbe Formulas and CellCore Biosciences and loves to research to formulate products that will change the world. Dr. Watts was the first to bring Mimosa Pudica seed to the general health market in the US. He has an amazing health journey, which has led him to be able to help others.

Dr. Peter Kan explains the brain-immune-gut connection and how to reverse chronic illness using a root-cause roadmap.

Dr. Peter Kan introduces the brain-immune-gut framework as a new way to understand chronic illness. He explains how dysfunction in any one of these systems—brain, immune, or gut—can spread to the others, driving inflammation, autoimmunity, and neurological symptoms. He outlines how vagus nerve function, blood sugar stability, oxygen delivery, and proper sequencing of care are foundational to sustainable healing.

Dr. Kan supports and manages patients with chronic conditions using a comprehensive approach by merging the exciting advances of functional neurology and functional medicine. Dr. Kan is Board Certified in Integrative Medicine, Functional Medicine, and a Board Certified Chiropractic Neurologist. He is the creator of NeuroMetabolic Integration, a virtual functional medicine program that identifies the root cause of autoimmune and other chronic conditions. Over 5000 patients from across the country have come to seek out his holistic approach that is changing the lives of those suffering from chronic conditions. Born in Taiwan and immigrating to America at the age of 13, Dr. Kan has a deep appreciation of the Eastern wisdom and Western advances in natural healthcare. He believes in the God-given ability of the body to heal and regulate itself.

Ashok Gupta explains how limbic retraining calms mast cell activation, rewires stress responses, and restores nervous system balance.

Ashok Gupta shares his personal recovery from chronic fatigue syndrome and explains how limbic system dysfunction can drive mast cell activation and chronic illness. He outlines how the brain’s threat detection system becomes overactivated, leading to exaggerated immune responses, and how structured neuroplasticity practices can calm the nervous system, retrain stress pathways, and support long-term healing alongside conventional and functional care.

Ashok Gupta is an internationally renowned Speaker, Filmmaker & Health Practitioner who has dedicated his life to supporting people through chronic illness, and achieving their potential. Ashok suffered from ME, or Chronic Fatigue Syndrome, around 25 years ago when he was studying at Cambridge University.

Through neurological research that he conducted, he managed to get himself 100% better. He then set up a clinic to treat others and published the well-known recovery program known as the Gupta Program in 2007. it now has 5 independent randomised controlled trials demonstrating its efficacy for ME/CFS, Long Covid, Fibromyalgia, Mold illness, Lyme, and many more.

He has published several medical papers and is continually researching these conditions. You can find out more information at www.guptaprogram.com.