The Beautifully Broken Podcast

From Transplant to Trailblazer: Mark Durante’s Exosome Breakthrough in Regenerative Medicine


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Nine years ago, Mark Durante received a heart transplant that saved his life—but it was just the beginning of his healing journey. When post-transplant neuropathy nearly disabled him, he turned to a friend in stem cell research. What happened next changed everything.
This episode dives deep into how exosomes work, what makes 3D manufacturing a breakthrough, and why regenerative medicine isn’t just for the rich and famous anymore. We compare exosomes to stem cells, explore cost and accessibility, and look at the growing global research. Whether you're a practitioner or just health-curious, this conversation might change the way you think about aging, healing, and what’s possible for the human body.

HIGHLIGHTS

[01:10] – Mark’s heart transplant story and how post-op pain led to a regenerative medicine journey
[02:45] – Discovering exosomes through stem cell therapy and getting off neurological meds
[05:22] – The birth of Rise Up Medical and turning healing into purpose
[09:00] – Exosomes 101: what they are and why they matter
[11:30] – Stem cells vs exosomes: when and why they’re used
[16:00] – The 3D manufacturing breakthrough and why it changes everything
[22:30] – Use cases: from arthritis to anti-aging to advanced neurological support
[29:00] – What regenerative treatments cost—and why smart dosing matters
[34:40] – How to find a practitioner or get your doctor on board
[43:00] – Global studies, real results, and what's coming next in regenerative care

GUEST RESOURCES

Rize Up Medical: https://www.rizeupmedical.com
Contact Mark’s Team: 469-269-0844
Instagram: https://www.instagram.com/rizeupmedical

Upgrade Your Wellness

BEAM Minerals: http://beamminerals.com/beautifullybroken
Use code beautifullybroken for 20% off

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30% off Use Code: BEAUTIFULLYBROKEN for Discount

StemRegen: https://www.stemregen.co/products/stemregen?_ef_transaction_id=&oid=1&affid=52
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LightPathLED: https://lightpathled.pxf.io/c/3438432/2059835/25794
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CONNECT WITH FREDDIE

Work with Me: https://www.beautifullybroken.world/biological-blueprint

Website and Store: (http://www.beautifullybroken.world)  

Instagram: (https://www.instagram.com/beautifullybroken.world/)  

YouTube: (https://www.youtube.com/@BeautifullyBrokenWorld)

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The Beautifully Broken PodcastBy Freddie Kimmel

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