In this eye-opening chronicle of scientific research on the brain in the early Cold War era, the acclaimed historian Andreas Killen traces the complex circumstances surrounding the genesis of our present-day fascination with this organ.

The 1950s were a transformative, even revolutionary decade in the history of brain science. Using new techniques for probing brain activity and function, researchers in neurosurgery, psychiatry, and psychology achieved dramatic breakthroughs in the treatment of illnesses like epilepsy and schizophrenia, as well as the understanding of such faculties as memory and perception. Memory was the site of particularly startling discoveries. As one researcher wrote to another in the middle of that decade, “Memory was the sleeping beauty of the brain—and now she is awake.” Collectively, these advances prefigured the emergence of the field of neuroscience at the end of the twentieth century.

But the 1950s also marked the beginning of the Cold War and a period of transformative social change across Western society. These developments resulted in unease and paranoia. Mysterious new afflictions—none more mystifying than “brainwashing”—also appeared at this time. Faced with the discovery that, as one leading psychiatrist put it, “the human personality is not as stable as we often assume,” many researchers in the sciences of brain and behavior joined the effort to understand these conditions. They devised ingenious and sometimes transgressive experimental methods for studying and proposing countermeasures to the problem of Communist mind control. Some of these procedures took on a strange life of their own, escaping the confines of the research lab to become part of 1960s counterculture. Much later, in the early 2000s, they resurfaced in the War on Terror.

These stories, often told separately, are brought together by the historian Andreas Killen in this chronicle of the brain’s mid-twentieth-century emergence as both a new research frontier and an organ whose integrity and capacities—especially that of memory—were imagined as uniquely imperiled in the 1950s. Nervous Systems: Brain Science in the Early Cold War (Harper, 2023) explores the anxious context in which the mid-century sciences of the brain took shape and reveals the deeply ambivalent history that lies behind our contemporary understanding of this organ.

Paul Lerner is Professor of History at the University of Southern California where he directs the Max Kade Institute for Austrian-German-Swiss Studies. He can be reached at [email protected] and @PFLerner.

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How healthy you are is dependent on where you live. Americans suffer more cancers, heart disease, mental illness, and other chronic diseases than those who live in other wealthy nations, despite having the most expensive healthcare system in the world. Why? Embark on a journey to unravel the profound impact of public policies on American health from before birth in Born Sick in the USA: Improving the Health of a Nation (Cambridge UP, 2026). Delve into the intricate web where economic inequality weaves a tapestry of sickness stemming from a highly stressed society. This compelling read illuminates the need for transformative change in social safety nets and public policies to uplift national health and well-being. Through vivid storytelling, the book unveils the symptoms, diagnosis, and 'medicine' required to steer the nation toward a healthier future. Join the movement for a healthier America by embracing the insightful revelations and empowering calls to action presented within the pages of this eye-opening book. Contact the author at: [email protected] 

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In the seventeenth and eighteenth centuries, venereal disease, or the 'pox,' was a dreaded diagnosis throughout Europe. Its ghastly marks, along with their inexorable link to sex, were so stigmatizing that it was commonly called 'the secret disease.' How do we capture everyday experiences of a disease that so few people admitted having? In The Dreaded Pox: Sex and Disease in Early Modern London (Cambridge UP, 2026), Dr. Olivia Weisser presents a remarkable history that invites readers into the teeming, vibrant pox-riddled streets of early modern London. She uncovers the lives of the poxed elite as well as of the maidservants and prostitutes who left few words behind, showing how marks of the disease offered a language for expressing acts that were otherwise unutterable. This new history of sex, stigma, and daily urban life takes readers down alleys where healers peddled their tinctures, enters kitchens and gardens where ordinary sufferers made cures, and listens in on intimate exchanges between patients and healers in homes and in taverns.

This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda’s interviews on New Books with Miranda Melcher, wherever you get your podcasts.

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Jonathan Gleason spent ten years writing the ten essays in his debut collection, Field Guide to Falling Ill (Yale UP, 2026). In them, Gleason braids together strands from a variety of sources – from his experience with a potentially-lethal blood clot, to his imprisoned uncle, to his journey to access medication to prevent HIV – to analyze America’s healthcare system and the humiliating, confusing, and depersonalizing effects it can often have. The essays approach medicine from a variety of viewpoints, from Jonathan’s perspective as a gay man analyzing the development of HIV medications like AZT and Truvada, to his experience as a Spanish language medical interpreter at a free clinic in Iowa City. But each essay also reminds readers of the importance of understanding the history of our healthcare institutions, and the necessity of feeling less alone when confronted by their myriad failures. Lyrical, poignant, and deeply human, Field Guide to Falling Ill is a poetic approach to understanding medicine in America.

For more information on Jonathan and his writing, visit:

Jonathan’s website: here

Jonathan’s Substack, Histories of Present Illness: here 
Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). Her new book, Addiction, Inc.: Medication-Assisted Treatment and America's Forgotten War on Drugs, will be released in April 2026.

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Using the narratives of women who use(d) drugs, this account challenges popular understandings of Appalachia spread by such pundits as JD Vance by documenting how women, families, and communities cope with generational systems of oppression. Prescription opioids are associated with rising rates of overdose deaths and hepatitis C and HIV infection in the US, including in rural Central Appalachia. Yet there is a dearth of studies examining rural opioid use.

RX Appalachia: Stories of Treatment and Survival in Rural Kentucky (Haymarket, 2020) explores the gendered inequalities that situate women’s encounters with substance abuse treatment as well as additional state interventions targeted at women who use drugs in one of the most impoverished regions in the US.

Lesly-Marie Buer is a harm reductionist and medical anthropologist in Knoxville, TN.

Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context.

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Mark Parrino has been involved with the delivery of health care and treatment for opioid use disorder (OUD) since 1974. As the president of the American Association for the Treatment of Opioid Dependence, Inc. (AATOD), he works with treatment providers across the country to develop and improve treatment protocols.

In December 2022, AATOD worked with the National Association of State Alcohol and Drug Abuse Directors (NASADAD) to initiate a first-of-its-kind census of all patients currently receiving treatment from government-certified opioid treatment programs (OTPs). Their findings, based on responses from over 1,500 OTPs nationwide, show the breadth and distribution of addiction treatment in America, and are the product of almost fifty years of medication-assisted treatment (MAT) in the United States.

I spoke with Mark about his census results, as well as the history of MAT, and specifically methadone, treatment in America. You can see the full report here.

Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, her second book, on the development of the opioid addiction medication industry, is under contract with the University of Chicago Press.

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Habitual drug use in the United States is at least as old as the nation itself. Elizabeth Kelly Gray's book Habit Forming: Drug Addiction in America, 1776-1914 (Oxford UP, 2023) traces the history of unregulated drug use and dependency before 1914, when the Harrison Narcotic Tax Act limited sales of opiates and cocaine under US law. Many Americans used opiates and other drugs medically and became addicted. Some tried ‘Hasheesh Candy’, injected morphine, or visited opium dens, but neither use nor addiction was linked to crime, due to the dearth of restrictive laws. After the Civil War, American presses published extensively about domestic addiction. Later in the nineteenth century, many people used cocaine and heroin as medicine.

As addiction became a major public health issue, commentators typically sympathized with white, middle-class drug users, while criticizing such use by poor or working-class people and people of color. When habituation was associated with middle-class morphine users, few advocated for restricted drug access. By the 1910s, as use was increasingly associated with poor young men, support for regulations increased. In outlawing users' access to habit-forming drugs at the national level, a public health problem became a larger legal and social problem, one with an enduring influence on American drug laws and their enforcement.

Rachel Pagones is an acupuncturist, educator, and author based in Cambridge, England. She was chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego before moving to the UK.

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The Mask: A History of Breathing Bad Air (Yale UP, 2025) by Dr. Bruno J. Strasser and Dr. Thomas Schlich presents a history of masks protecting against bad air—in cities, factories, hospitals, and war trenches—exploring how our identities and beliefs shape the decision to wear a mask.

For centuries, humans have sought to protect themselves from harmful air, whether from smoke, dust, vapors, or germs. This book offers the first history of respiratory masks—ranging from simple pieces of cloth to elaborate gas masks—and explores why they have sparked both hope and fear.

Dr. Strasser and Dr. Schlich captivate readers with stories of individuals—from renowned doctors and political leaders to forgotten inventors and anonymous factory workers—who passionately debated the value of masks. In Renaissance Italy and Meiji Japan, in Victorian Britain and Cold War America, the way societies have engaged with face coverings reveals their deepest cultural and political fractures. The Mask challenges us to reconsider how we care for one another and the kind of environment we aspire to inhabit.

This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda’s interviews on New Books with Miranda Melcher, wherever you get your podcasts.

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Clare Griffin's book Mixing Medicines: The Global Drug Trade and Early Modern Russia (McGill-Queen's UP, 2022) introduces the reader to the dynamic and complex world of early modern Russian medical drugs, from the enthusiasm for newly imported American botanicals to the disgust at Western European medicines made from human corpses.

Based on a unique set of previously unused sources, this book is the first study of how the Russian Empire took part in the early modern global trade in medical drugs. The extensive and detailed records kept by the Moscow court show how ingredients produced elsewhere and passed through the massive, long-distance trade network of the early modern world were finally consumed. Looking at medicine as materia medica gives us a different perspective than when looking at practitioners, texts, and ideas.

Erika Monahan is the author of The Merchants of Siberia: Trade in Early Modern Eurasia (Cornell UP, 2016) and a 2023-2024 Alexander von Humboldt Fellow

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Cervical cancer kills almost 350,000 women each year. What's more horrifying, is that millions have died of this disease that's nearly 100% preventable. It's no secret that healthcare is full of inequities, with a severe lack of accessible screening programs. But women's health care is also impeded by cultural, gender, and political barriers, issues that have combined to create devastating consequences. 

In Enough: Because We Can Stop Cervical Cancer (Cambridge UP, 2024), Dr Linda Eckert takes her years of experience and weaves it together with the voices of the courageous women who use their own experience of cervical cancer to advocate for change. This heart-breaking, yet hopeful, book takes you through the world of cervical cancer with evidence-based information, personal stories and actionable outcomes. Society flourishes when women have access to safe and affordable healthcare. Together we can make this need a reality and eliminate the world's most preventable cancer.

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