Podcast Notes Playlist: Latest Episodes

• Check out Modern Wisdom Episode Page & Show Notes

Daniel Pink is a psychologist, speaker and an author.

Regret is the most common negative emotion humans talk about. It's even the second most common overall emotion which we talk about after love. And yet our relationship with it is pretty terrible. Having no regrets is not only a bad tattoo from the 90's but also a philosophy that robs of us valuable insights from life.

Expect to learn the most common types of regrets people have in life, whether action or inaction is the cause of most suffering, how Daniel suggests we can grow past our regrets, why never looking backward is limiting our growth, how people believe in both free will and things happening for a reason and much more...

Sponsors:

Join the Modern Wisdom Community to connect with me & other listeners - https://modernwisdom.locals.com/

Get 15% discount on Craftd London’s jewellery at https://bit.ly/cdwisdom (use code MW15)

Get 20% discount on the highest quality CBD Products from Pure Sport at https://bit.ly/cbdwisdom (use code: MW20)

Get a free v60 brewing kit and 40 filters from Pact Coffee at https://www.pactcoffee.com/ (use code: MODERNWISDOM)

Extra Stuff:

Buy The Power Of Regret - https://amzn.to/3I0UUx9

Follow Daniel on Twitter - https://twitter.com/DanielPink 

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

-

Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/ 

Onions have been a part of human history since long before records began. It's played a vital part in our diets, but also in our mythology, representing eternal life to some cultures, as well as playing a part in the origin stories of the stars. Onions are one of natures most versatile products and in this episode we dive deep into the role it's played throughout the ages.

-------------------

Please support me on Patreon: https://www.patreon.com/foodhistorypod and get early access to episodes, and bonus content.

Find transcripts and sources on the website: www.foodhistorypodcast.com

-------------------

• The goal is always to become more of who we are, not become something we’re not
• Challenge the system; look for new solutions to health and aging
• We’re on the brink of a major regenerative health movement
• If we tackle aging upstream, we have a shot at solving problems at the root cause
• It’s worth the time and expense to invest in diagnostics not covered by traditional insurance – you’ll have a better shot at catching problems early and setting yourself up for successful intervention

• The way we respond to a diet is highly individualized – people uniquely respond to diet, even if fed the exact same foods
• “The dominant factor that determines the diurnal activity of microbes throughout the day is the timing of our feeding.” – Dr. Eran Elinav
• Our gut microbiome senses when we eat or don’t eat and changes activity accordingly
• Changes in health status, stress status, medication, the way we live, where we live, etc. reflect on our gut microbes and may impact the risk of developing diseases
• A leaky gut is related to disease: diverse molecules secreted by the gut microbe are important in creating the normal state of leakiness which allows us to absorb food and block foreign molecules we don’t want in our body – when disrupted, there’s a strong link to disease (cancer, autoimmune & cardiovascular disease)
• The success of probiotic supplementation depends on whether the exogenous probiotic is welcomed by endogenous microbes in the gut
• The complexity of taking antibiotics and probiotics: giving probiotics together with antibiotics may protect individuals from adverse effects of antibiotics – but the price may be a chronic disturbance in gut microbiome with probiotics taking over and reducing the diversity of the innate gut microbiome
• About 80% of overweight people who diet will gain back the weight plus some – the microbiome seems to store a metabolic memory of past obesity which predisposes people to exaggerated weight gain
• Best practices for a healthy microbiome: (1) maintain a consistent, healthy sleep pattern; (2) stop smoking cigarettes; (3) eat during a regular window during the day (avoid night eating); (4) explore wearing a continuous glucose monitor for personalized data; (5) try a personalized nutrition approach (check out Day Two)

Eran Elinav, MD, PhD, is a professor of immunology and principal investigator at the Weizmann Institute of Science in Tel Aviv, Israel, where he co-directs the Personalized Nutrition Project. Dr. Elinav is also a principal investigator at the German Cancer Research Center in Heidelberg, Germany. His research focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease.

In this episode, Dr. Elinav and I discuss...

• 00:06:38 - Circadian rhythm of the microbiome
• 00:17:17 - Lessons from Hunter-gatherers
• 00:24:44 - Nurturing the microbiome in children
• 00:35:16 - Triglycerides and cholesterol
• 00:38:58 - Saturated fat
• 00:40:25 - Effect of artificial sweeteners on the microbiome
• 00:56:10 - What causes recurrent obesity
• 00:58:17 - Impact of caloric restriction
• 00:59:26 - Intestinal permeability (gut leakiness)
• 01:19:54 - Bacteriophage therapy and precision probiotics
• 01:34:44 - Bacterial role in TMAO risk
• 01:40:33 - Weight gain from smoking cessation
• 01:41:53 - Tips for diet personalization

Looking for more? 
Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

Try thirty days of our FoundMyFitness premium member to get access to exclusive episodes, emails, a live Q+A with Rhonda and more: https://www.foundmyfitness.com/trial

• “Place your biggest bet on a focused strategy and iterate until it works” – Aaron Levietweet
  • Never hedge your bets as a company – if you have two paths, you have no paths
  • You have limited resources, don’t lower your ceiling with two bets
• Design and innovation are directly influenced by the architecture of your organization, it’s important to know your identity
  • Amazon: decentralized with an innovation focus
  • Apple: centralized with a design focus
• Serial entrepreneurship is overrated
  • Choosing the right market at the right moment is more valuable than any years of experience
• Network design comparison: Airbnb vs Crypto
  • Crypto networks experience a value plateau as new participants have less and less upside
  • Airbnb users and hosts gain more value when the network grows, regardless of when you joined

Aaron Levie is the Founder and CEO @ Box, the company incorporating the best of secure content collaboration with an intuitive user experience suited to the way people work today. Prior to their IPO in 2015, Aaron raised from some of the best in the business including the main man Mark Cuban, a16z, Emergence, DST, Coatue, DFJ and many more. Aaron founded the company from his dorm room at the University of Southern California and has led the company to 1,900 employees and over $770M in revenue, as of 2021 data.

1.) How Aaron founded Box from his dorm room at the University of Southern California? What was that founding a-ha moment? What did the first year look like? Does Aaron agree, "serial entrepreneurship is overrated"?

2.) Phases of Leadership and Company Growth:

• How does Aaron define the different phases of leadership required as a company grows?
• Which phase did Aaron find the most challenging? How did he overcome it?
• What are the first things to break when companies grow? What can founders do to prevent this?
• Does Aaron agree, "the best CEOs are the best resource allocators"?

3.) The Market:

• How does Aaron thinkj about the dislocation between private company valuations and public company market caps?
• What does Aaron believe are the biggest challenges founders face when they are over-capitalised?
• What does Aaron mean when he says, "raise when cash is cheap, spend as if it was expensive"? How does Aaron advise founders on fundraising today?

4.) The Team and Culture:

• How does Aaron create a safe space where all team members can come to him with anything?
• How does Aaron approach effective goal setting? How does one balance between achieveable and also aggressive goals?
• How does Aaron approach the art of delegation? What is his decision-making framework for what to delegate vs what to control?

Aaron’s Favourite Book: Innovator's Dilemma: When New Technologies Cause Great Firms to Fail (Management of Innovation and Change)