The Dr. Hyman Show

By Dr. Mark HymanMedicine Health & Fitness Nutrition

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The Dr. Hyman Show episodes

February 02 Office Hours: Cholesterol and Heart Disease — What I’ve Changed My Mind About
For decades, we’ve been told that high cholesterol is the main driver of heart disease—and that lowering LDL should be the primary goal. But as science has evolved, so has my thinking. In today’s Office Hours, I explain why cholesterol alone doesn’t tell the full story, what most doctors still aren’t testing, and what’s really driving heart disease for the majority of people.
Today we discuss:
• Why many people have heart attacks despite “normal” LDL cholesterol
• The difference between cholesterol levels and cholesterol particles
• How inflammation and insulin resistance fuel heart disease
• Why sugar and refined starches are more dangerous than fat
• The most important labs to assess real cardiovascular risk
• What ApoB, lipoprotein(a), and triglyceride-to-HDL ratio reveal about your health
• How metabolic dysfunction—not cholesterol alone—drives plaque buildup
Heart disease is far more complex than a single lab value. When you understand the role of metabolic health, inflammation, and the right biomarkers, you can take meaningful steps to protect your heart and long-term health.
Visit ⁠functionhealth.com⁠ for 160+ lab tests at just $365 a year.
Helpful Resources:
Join the 10-Day Detox to Reset Your Metabolic Health
https://drhyman.com/pages/10-day-detox
Have a question you’d love answered on Office Hours? Submit it here 👉https://docs.google.com/forms/d/e/1FAIpQLSdNF2y4lFWEOMLlzVNlFDpJ4xl7oOpH9NlImMoHr5mHggL_Ww/viewform?usp=header
31 min
January 28 Why Men’s Fertility Is Collapsing and What It Means for Our Future | Dr. Michael L. Eisenberg
Around the world, we’re seeing declining sperm counts, rising infertility, more erectile dysfunction, and lower testosterone—even in younger men.
These trends aren’t just affecting family planning; they’re pointing to something much bigger happening in men’s health.
Joining me today on The Dr. Hyman Show is Dr. Michael Eisenberg, a Stanford researcher and leading voice in male reproductive health. We talk about why sperm quality matters far beyond fertility—and how everyday health choices quietly shape it. Watch the full conversation on YouTube or listen wherever you get your podcasts.
[YOUTUBE THUMBNAIL]
We cover:
• Why sperm quality may be one of the strongest early indicators of overall health and longevity
• How metabolic dysfunction, belly fat, and low testosterone impact fertility and sexual function
• The role environmental toxins and endocrine disruptors play in declining sperm counts
• What men can do right now to protect fertility and long-term vitality
When we look at fertility through the lens of whole-body health, it changes how we think about prevention, risk, and longevity. Male fertility isn’t just about reproduction. It’s a signal.
Register for The Ultra Learning Series: Functional Fertility on Thursday, February 12 at 12PM ET here.
View Show Notes From This Episode
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Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
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This episode is brought to you by Qualia, Seed, PerfectAmino, Sunlighten, BIOptimizers and Korrus.
Go to qualialife.com/hyman and use code HYMAN at checkout for an extra 15% off.
Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month.
Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order.
Visit sunlighten.com and use code HYMAN to save up to $1400.
Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%.Upgrade your lighting.
Enjoy 15% off at korrus.com/drhyman.

(0:00) Rise in male infertility and testosterone issues
(1:24) Global challenges in men's health and infertility awareness
(4:56) Decline in semen quality and potential causes
(9:52) Reducing exposure to endocrine disruptors and detoxification methods
(14:51) Metabolic health's impact on testosterone and sperm quality as a vital sign
(21:00) Sperm quality biomarkers and the impact of paternal age on offspring
(26:28) Role of paternal health and epigenetics in pregnancy outcomes
(31:29) Lifestyle and supplements to improve sperm quality
(37:57) Stress and environmental factors affecting hormone levels and birth sex ratios
(41:05) Erectile dysfunction: rates, causes, and treatment options
(51:22) Testosterone replacement therapy: benefits and risks
(1:00:08) Andropause and epigenetics in reproductive health
(1:08:22) Rapid fire questions: lifestyle factors affecting sperm quality
(1:09:45) Impact of cycling and sedentary lifestyle on reproductive health
(1:12:46) Importance of sleep, stress management, and relaxation techniques
(1:13:45) Information about swim club and supplements for fertility
(1:14:44) Introduction to the Ultra Learning Series and functional fertility workshop
(1:16:07) Disclaimer and gratitude to sponsors

1 hr 21 min
January 26 Office Hours: Preparing Your Body for Pregnancy — Fertility, Nutrition & Hormones
What’s Really Driving Infertility—and What You Can Do About It
Fertility struggles are far more common than most people realize—and far more complex than we’re often told. Today I answer listener-submitted questions on fertility, hormone balance, and preparing your body for conception.
Here’s what I cover:
• Why infertility is rising and what’s really driving it
• The hidden role of blood sugar, inflammation, and toxins in hormone balance
• What to do if labs are “normal” but fertility struggles persist
• How lifestyle and nutrition improve egg and sperm quality
• Simple, practical steps to support fertility now and long-term
Fertility challenges are complex and often influenced by underlying imbalances. Addressing root causes can help support your body’s natural resilience over time.
Visit ⁠functionhealth.com⁠ for 160+ lab tests at just $365 a year.
Helpful Resources:
Grab Our FREE Fertility Blueprint: 7 Daily Practices That Support Conception
https://drhyman.com/products/fertility-blueprint?_pos=1&_psq=fertility&_ss=e&_v=1.0

What to Eat (and Avoid) When You’re Trying to Conceive Guide: https://drhyman.com/pages/what-to-eat-when-ttc-guide
Join the 10-Day Detox to Reset Your Metabolic Health
https://drhyman.com/pages/10-day-detox
Register for The Ultra Learning Series: Functional Fertility on Thursday, February 12 at 12PM ET here: https://us06web.zoom.us/webinar/register/WN_D-Tzh9z8QmyQdZpBOgohKQ#/registration
Have a question you’d love answered on Office Hours? Submit it here 👉https://docs.google.com/forms/d/e/1FAIpQLSdNF2y4lFWEOMLlzVNlFDpJ4xl7oOpH9NlImMoHr5mHggL_Ww/viewform?usp=header

37 min
January 21 Fix the Brain, Change the Mind: Root-Cause Psychiatry with Dr. Robert Hedaya
On this episode of The Dr. Hyman Show, I sit down with Dr. Robert Hedaya, a psychiatrist who has spent decades working at the intersection of biology, brain function, and mental health. His approach starts with a different question than most psychiatry asks: what’s interfering with the brain’s ability to regulate, adapt, and repair itself?
We talk about why many mental health diagnoses describe symptoms without explaining causes—and how measuring brain function, energy, and network activity is opening the door to more precise, individualized care.
Watch the full conversation on YouTube or listen wherever you get your podcasts.
[YOUTUBE THUMBNAIL]
We discuss:
• How biological imbalances can drive anxiety, depression, and cognitive symptoms
• Why many “treatment-resistant” mental health issues have overlooked root causes
• How brain energy and mitochondrial function influence mood and cognition
• What advanced brain mapping reveals about how your brain is actually working
For far too long, mental health care has focused on managing symptoms in isolation. This discussion looks at what becomes possible when we treat the brain as part of the whole system and support its ability to heal.
View Show Notes From This Episode
Get Free Weekly Health Tips from Dr. Hyman
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Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
This episode is brought to you by Seed, Sunlighten, Timeline, Paleovalley, Fatty15 and Pique.
Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month.
Visit sunlighten.com and use code HYMAN to save up to $1400.
Receive 35% off a subscription at timeline.com/drhyman.
Head to paleovalley.com and use code HYMAN20 for 20% off your first order.
Visit fatty15.com/hyman and use code HYMAN to save an extra 15% on a 90-day subscription.
Secure 20% off your order plus a free starter kit at piquelife.com/hyman.
1 hr 11 min
January 19 Office Hours: Answering Your Questions on the New Dietary Guidelines
In this Office Hours episode, I break down what the government finally got right about food, where the new guidelines still fall short, and—most importantly—how to apply them in real life without confusion or overwhelm. For the first time in decades, there’s meaningful progress: a recognition that ultra-processed foods are harming us, that protein matters for optimal health, and that nutrition isn’t one-size-fits-all. But there’s still work to do.
In this episode, I break down:
• Why calling out ultra-processed foods is the most important—and historic—shift in the new guidelines
• What the new protein recommendations actually mean for everyday people
• Why the low-fat era is finally ending—and why whole foods matter more than isolated nutrients
• Where the guidelines still fall short, including saturated fat limits, whole grain recommendations, and lack of personalization
• How to apply the guidelines to kids and families without perfection or overwhelm
• Why chronic disease is a policy problem—not a personal failure
The new dietary guidelines are a foundation, not a finish line. Use them as a starting point: focus on food quality, reduce ultra-processed foods, prioritize protein, and personalize your choices based on how your body responds.
Visit ⁠functionhealth.com⁠ for 160+ lab tests at just $365 a year.
Helpful Resources:
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Nutrition 101: The Foundation of Feeling Your Best
https://drhyman.com/pages/nutrition-101
Pre-order my book, Food Fix Uncensored:
https://drhyman.com/pages/food-fix
Have a question you’d love answered on Office Hours? Submit it here 👉https://docs.google.com/forms/d/e/1FAIpQLSdNF2y4lFWEOMLlzVNlFDpJ4xl7oOpH9NlImMoHr5mHggL_Ww/viewform?usp=header
28 min
January 14 Muscle Is the Key to Longevity (Not Fat Loss) | Dr. Gabrielle Lyon
Longevity isn’t just about what you eat or how you train—it’s really more about whether you believe your body is worth investing in.
On this episode of The Dr. Hyman Show, I’m joined by my longtime friend and colleague Dr. Gabrielle Lyon to explore why muscle may be one of the most overlooked drivers of long-term health. We focus on practical, accessible ways to build strength as you age, and why muscle plays a much bigger role in your health than most people realize.
We explore:
• How strength training supports your blood sugar and metabolic health, beyond what the scale can show
• Why muscle quality—not weight—is a stronger predictor of long-term health
• How building strength helps you stay mobile, capable, and resilient as you age
• What most people miss about protein and muscle health
Aging well is something you can actively support, starting with how you care for your body today. And strength is one of the most powerful places you can begin.
View Show Notes From This Episode
Get Free Weekly Health Tips from Dr. Hyman
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Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive

This episode is brought to you by Timeline, PerfectAmino, BIOptimizers, Mau Nui, Made In Cookware and BON CHARGE.
Receive 35% off off a subscription at timeline.com/drhyman.
Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order.
Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%.
Learn more about the health benefits of venison and how to get yours, head over to mauinuivenison.com/hyman.
Head to madeincookware.com and use the code HYMAN for 10% off your order.
Upgrade your routine. Head to boncharge.com/hyman and use code DRMARK for 15% off.

(0:00) Introduction and Dr. Gabrielle Lyon's background
(1:00) Protein's importance across ages and muscle benefits
(3:28) Muscle: A neglected organ and its metabolic roles
(8:01) Assessing muscle quality and functional health
(13:09) Resistance training and muscle rejuvenation strategies
(19:33) Muscle's immune and hormonal functions
(22:29) Myokines and body composition analysis
(26:17) Strength training and innovative techniques
(32:05) Muscle as the organ of longevity and protein's significance
(38:12) Dietary guidelines and protein requirement debates
(48:08) Amino acids, protein turnover, and intake strategies
(59:48) Metabolic flexibility and creatine's benefits
(1:00:21) Sponsor: Timeline's research on urolithin A
(1:02:20) Mitochondrial health and muscle-centric medicine
(1:08:14) Muscle health's mismatch with chronic diseases
(1:10:20) Dr. Lyon's longevity practices and quickfire questions
(1:16:03) Strength's importance during menopause and cold exposure
(1:18:51) Dr. Lyon's career highlights and resources
(1:20:17) Closing remarks and disclaimers

1 hr 25 min
January 12 Office Hours: How to Choose the Best Diet for Your Body
What Should I Actually Eat?
Diet confusion is everywhere. But the truth is, there’s no one-size-fits-all diet. The best diet is the one that works for your biology. In this Office Hours episode, I answer your most common diet questions and break down the core principles everyone should understand before choosing how to eat.
In this episode I break down:
• Why the “best diet” is personalized—and why ideology should never override biology
• The universal principles everyone should follow, regardless of diet
• Why ultra-processed foods—not carbs, fat, or protein—are the real problem
• How blood sugar dysregulation drives chronic disease, including mental health issues
• Keto, paleo, vegan, and Mediterranean: who they help, common mistakes, and what to watch for
• How to tell if your diet is working—using symptoms, energy, digestion, mood, and labs
Your body is the smartest doctor in the room. The key is learning how to listen.
Visit ⁠functionhealth.com⁠ for 160+ lab tests at just $365 a year.
Helpful Resources:
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Have a question you’d love answered on Office Hours? Submit it here 👉 https://docs.google.com/forms/d/e/1FAIpQLSdNF2y4lFWEOMLlzVNlFDpJ4xl7oOpH9NlImMoHr5mHggL_Ww/viewform?usp=header
35 min
January 07 Why Mental Illness Is a Metabolic Problem—and What That Means for Your Health | Dr. Chris Palmer
On this episode of The Dr. Hyman Show, I’m rejoined by psychiatrist and Harvard professor Dr. Chris Palmer for a conversation that challenges how we’ve been taught to think about mental illness.
For decades, psychiatry has focused on managing symptoms—often without asking what’s actually driving them. We discuss a different way of understanding mental health, one that looks beyond diagnostic labels and considers how whole-body biology influences brain function, resilience, and recovery.
Watch the full conversation on YouTube or listen wherever you get your podcasts.
In this conversation, we explore:
• Why mental illness is rising alongside obesity, diabetes, and other chronic diseases
• How whole-body biology influences mood, focus, and emotional resilience
• The link between inflammation, metabolic dysfunction, and conditions like depression and bipolar disorder
• How nutrition, testing, and lifestyle changes can support real recovery
If mental health has ever felt close to home for you or someone you care about, this conversation is meant to offer clarity, compassion, and a place to start.
This episode was recorded live at the Eudēmonia Summit, a conference exploring the future of health, longevity, and well-being. Learn more at eudemonia.net.
View Show Notes From This Episode
Get Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
This episode is brought to you by Timeline, BON CHARGE, Qualia, Paleovalley, Pique and Korrus.
Receive 35% off a subscription at timeline.com/drhyman.
Upgrade your routine. Head to boncharge.com/hyman and use code DRMARK for 15% off.
Go to qualialife.com/hyman and use code HYMAN at checkout for an extra 15% off.
Head to paleovalley.com and use code HYMAN20 for 20% off your first order.
Secure 20% off your order plus a free starter kit at piquelife.com/hyman.Upgrade your lighting.
Enjoy 15% off at korrus.com/drhyman.

(0:00) Introduction to mental health crisis and guest Dr. Christopher Palmer
(1:31) Eudaimonia Summit and psychiatric revolution
(3:06) Traditional and systemic views on psychiatric disorders
(7:23) Misconceptions and stigma surrounding mental disorders
(10:15) The impact of childhood experiences on mental health
(13:28) Root causes of mental illness: Inflammation and brain dysfunction
(21:23) Metabolic dysfunction in mental illness
(24:15) Significance of metabolism in mental health
(27:47) Metabolic nutritional psychiatry and premature mortality
(32:34) The mental health revolution and metabolic treatments
(34:16) Ketogenic diet as a potential treatment for mental disorders
(37:18) Functional and network medicine in mental health
(41:13) Biomarkers and potential treatments in metabolic mental health
(49:07) Ketogenic therapy and its anti-inflammatory effects
(50:12) Historical and emerging paradigms in psychiatry
(54:38) Integrating functional medicine into mainstream psychiatry
(56:20) Addressing chronic disease in national health discussions
(58:22) Closing remarks and further resources
(59:02) Podcast outro and call to action

1 hr 4 min
January 05 Office Hours: What Happens to Your Body When You Stop Drinking for 30 Days
Most of us don’t realize how much alcohol affects our bodies until we take a break. In this first episode of Office Hours, I break down what really happens when you give up alcohol for 30 days. Alcohol impacts nearly every system—from your brain and hormones to your gut, liver, and immune system—but the good news is your body begins repairing itself far faster than most people expect.
I discuss:
• What alcohol really is—and why the “buzz” is actually your brain slowing down
• How alcohol affects neurotransmitters like GABA, dopamine, and glutamate
• Why even moderate drinking disrupts sleep, mood, hormones, and metabolism
• How alcohol impacts the liver, gut microbiome, immune system, and cancer risk
• Why hangovers feel like the flu—and what’s actually happening in your body
• What happens when you stop drinking, week by week, from detox to deep repair
• The surprising benefits to energy, focus, skin, sleep, and emotional resilience
• Practical tools to manage cravings, social pressure, and sleep disruption
• Why community support makes behavior change easier and more sustainable
Your body has an incredible ability to heal and often, it just needs you to take your foot off the gas. Try it for 30 days. You may be amazed by how different you feel.
If you want extra support, join us for the Hive January Challenge, where we’ll guide you through the process, track progress, and share experiences together.
Visit functionhealth.com for 160+ lab tests at just $365 a year.
Helpful Resources:
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
Have a question you’d love answered on the podcast? Submit it here 👉 https://docs.google.com/forms/d/e/1FAIpQLSdNF2y4lFWEOMLlzVNlFDpJ4xl7oOpH9NlImMoHr5mHggL_Ww/viewform?usp=header

(0:12) Introduction and the power of personal health agency
(0:51) Joining the Hyman Hive community and dry January benefits
(2:07) Understanding the broad effects of alcohol on health
(7:27) Long-term health consequences of alcohol use
(13:13) Alcohol's link to hangovers and cancer risk
(15:31) The positive changes from abstaining alcohol
(17:13) Emphasizing mindful alcohol consumption and community support
(18:45) Conclusion and invitation for listener feedback

23 min
December 31, 2025 Are You Nutrient Deficient? The Hidden Factors of Accelerated Aging | Rhonda Patrick - ENCORE
This week, in another holiday edition of The Dr. Hyman Show, I’m highlighting a conversation with Dr. Rhonda Patrick, a leading expert in nutritional science and aging — a discussion that still feels incredibly important today. We dig into how hidden micronutrient deficiencies can influence metabolism, mood, longevity, and long-term health. Here’s to supporting our health in the year ahead.
In this episode, you’ll learn:
• Why vitamin D is essential for longevity, immune health, and mood
• How magnesium influences metabolism, blood sugar, and brain function
• Why even “healthy” diets can leave us undernourished
• What it takes to test and personalize your micronutrient intake
Better aging starts by giving your cells what they’re missing. When your body has the right nutrients, it can repair, renew, and thrive at any stage of life.
Here’s to a healthy start to the new year — I’m excited for what we’ll explore together.
View Show Notes From This Episode
Get Free Weekly Health Tips from Dr. Hyman
https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Healthhttps://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Resultshttps://drhyman.com/pages/hyman-hive
This episode is brought to you by Seed, PerfectAmino, Function Health, AirDoctor, LMNT and Pique.
Visit seed.com/hyman and use code 20HYMAN for 20% off your first month of Seed's DS-01® Daily Synbiotic.
Go to bodyhealth.com and use code HYMAN20 for 20% off your first order.
Join today at functionhealth.com/mark and use code MARK2026 to get $50 OFF toward your membership.
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1 hr 30 min

About The Dr. Hyman Show

From the publisher's feed

Welcome to The Dr. Hyman Show, the podcast helping you take ownership of your health and reimagine what’s possible. Hosted by Dr. Mark Hyman—physician, bestselling author, and pioneer in functional medicine—this show explores the most pressing issues of our time: chronic disease, nutrition, mental health, food policy, prevention, and longevity.