Many people don’t know this, but heart disease is the leading cause of death in women. In 2023, 1 in 5 women died from heart disease. Gwyneth sits down with Tara Narula, MD, a board certified cardiologist  and

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Gwyneth sits down with Dr. Dawn Mussallem, the chief medical officer for Fountain Life, a longevity clinic powered by AI. They talk about Dawn’s incredible health journey–from beating stage four non-Hodgkin lymphoma while in medical school to undergoing a heart transplant at 46–and how that experience now informs her work in the medical field and integrating the powers of AI into health care.

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How dangerous are microplastics for us really? And how can we avoid them in our own lives while also working to remove them from our community? Gwyneth sits down with environmental advocate and president of Beyond Plastics Judith Enck to talk about the ways we have been misinformed about microplastics and their true effect on our bodies and the environment.

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Gwyneth sits down with Matthew McConaughey to discuss Poems & Prayers, a collection of personal writings that trace his journey through reinvention, truth, and self-discovery.

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Gwyneth Paltrow takes a solo drive with Polestar and reflects on the rituals that ground her—from “boyfriend breakfast” to self-care.

She shares how these small, intentional practices can bring a sense of steadiness during times of uncertainty, helping us stay connected to ourselves—and, over time, become something we return to again and again, guiding us through some of life’s most difficult moments.

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Gwyneth sits down with Tig Notaro—comedian, writer, actor, and producer—to talk about her Oscar-nominated documentary Come See Me in the Good Light, which follows poet Andrea Gibson through the final chapter of their life.

They talk about friendship, illness, and mortality—and how everything can shift when you’re faced with what really matters. Tig reflects on witnessing Andrea’s humor, openness, and perspective in the face of stage four cancer, as well as her own experience with illness and loss—and how comedy became a way through it.

They also explore art as a way of making meaning, the strange coexistence of heartbreak and laughter, and why we shouldn’t wait for something devastating to start living more fully.

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Gwyneth sits down with Amanda Knox to reflect on life after global scrutiny—rebuilding her identity, processing the years she lost, and the extraordinary strength it takes to choose forgiveness.

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Gwyneth sits down with Andrew Huberman—neuroscientist, Stanford professor, and host of the Huberman Lab podcast—to explore the science behind some of the most talked-about topics in health right now, from protein intake and gut health to the emerging world of peptides. Huberman breaks down what the research actually says about how much protein we need, why the gut microbiome plays such a powerful role in inflammation and overall health, and how new therapies—from peptides to the latest metabolic treatments—are reshaping the conversation around recovery and weight loss. They also discuss circadian rhythms, sleep, and the everyday habits that help regulate the nervous system and allow us to work with our biology rather than against it.

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The Advice That Will Change How You Think About Success

In this episode from 2025, Gwyneth sits down with Emma Grede — founder of Good American, co-founder of Skims, and author of Start With Yourself — to talk about what it really takes to build an empire. Emma opens up about growing up in East London with no money, dropping out of school at 16, and betting on herself when no one else would. They get into why women need to stop being polite about money, what it really takes to lead with intention, and the daily gratitude practice she swears by.

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Emily Hickey—marketer and brand strategist—sits down with Gwyneth Paltrow to talk about personal codes, the inner principles that shape how we move through the world. They discuss reinvention, self-expression, and how aligning with your values can transform how you show up and bring clarity in moments of change.

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