Is the genetics industry full of BS? 

Joe Cohen sits down with Dr. Puya Yazdi, co-founder of SelfDecode, to expose the real science behind genetic testing, polygenic risk scores, and why most DNA reports are giving you half-truths (or worse—total garbage).

If you care about your health, longevity, and actually understanding what your genes say about you, this episode is a must-listen. 

Buckle up—this one's a game-changer.

- Check out SelfDecode: https://selfdecode.com/
- Join Joe’s online community: https://thejoecohenshow.com/

In this episode of The Joe Cohen Show, Joe dives into the world of probiotics and biohacking with a deep dive into Lactobacillus fermentum. He shares his personal experience megadosing this unique probiotic, which has been linked to boosting glutathione levels—one of the body's most powerful antioxidants. Joe discusses the science behind L. fermentum, its potential benefits, and whether he's noticed any significant effects. 

Tune in to explore the latest in supplementation, self-experimentation, and cutting-edge health optimization!

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

In this episode of The Joe Cohen Show, we take a deep dive into genetic reports, specifically analyzing the Wild Health Report. Joe breaks down the strengths and weaknesses of these reports, highlighting the common pitfalls in genetic testing and how they often analyze only a limited set of variants. He also introduces a new and improved alternative: the 100X Wildly Healthy Functional DNA Report. Tune in to discover what makes a genetic report truly effective, how to interpret DNA-based diet and nutrition insights, and why a more comprehensive approach can revolutionize personalized health optimization. Don't miss this insightful discussion on the cutting edge of biohacking and functional medicine!

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

In this episode of The Joe Cohen Show, Joe explores the science of air purification and why investing in the right air purifiers and air filters is essential for optimizing health. 

He breaks down how poor indoor air quality—filled with mold spores, VOCs, and airborne pollutants—can impact energy levels, cognitive function, and inflammation. 

Joe shares his biohacking approach to selecting the most effective air filtration systems, including the latest technology for achieving cleaner air at home. 

If you're looking to upgrade your air quality, reduce toxins, and take control of your environment, this episode is for you.

Buy the Air Purifiers:

AZEUS UV Light Air Purifier on Amazon

DAYETTE H14 Air Purifier on Amazon

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

Join host Joe Cohen as he sits down with biohacker, actress, and health influencer Melanie Avalon for an insightful discussion on women and biohacking.

Melanie shares her top biohacks, secrets to boosting performance, and even some surprising drinking biohacks. 

As the host of multiple health-focused podcasts, founder of AvalonX, and author of What, When, Wine, Melanie brings a wealth of knowledge on intermittent fasting, paleo-style nutrition, and longevity strategies. 

Get 10% OFF on https://avalonx.us/ by using coupon code ‘JOE’

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

In this episode of Should You Take This?, host Joe Cohen dives deep into Lactobacillus rhamnosus GG (L. Rhamnosus GG)—one of the most researched probiotic strains for gut health, brain function, and heart health.

Joe shares his megadosing experiment, where he took 375 billion CFU of L. Rhamnosus in one day—25x the standard dose—to test its effects on mood, cognition, digestion, and cardiovascular health. 

He breaks down the scientific research behind Lactobacillus rhamnosus, explaining how it can:

✔ Reduce excess glutamate and increase GABA, leading to improved mood and mental clarity✔ Lower TMAO levels, a metabolite linked to heart disease risk✔ Strengthen the gut barrier, improving digestion and immune function

He also explores the genetic link, explaining how SelfDecode flagged L. Rhamnosus as a top recommendation based on his unique DNA risks for neurotransmitter imbalance, inflammation, and metabolic health.

If you’re wondering whether Lactobacillus rhamnosus is the right probiotic for you, this episode breaks down the real-world benefits, genetic considerations, and optimal ways to take it.

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

In this episode of Should You Take This?, host Joe Cohen dives deep into one of his top three favorite probiotics—Bifidobacterium longum.

If you've struggled with bloating, digestion issues, or simply want to optimize your gut health, this probiotic might be a game-changer.

Joe shares his personal experience with B. longum, breaking down its effectiveness in reducing gas, improving digestion, and supporting overall health. He also explores the scientific research behind it, discussing its potential benefits for mood, immunity, and inflammation.

Tune in to learn whether B. longum is the right probiotic for you and how it fits into Joe’s biohacking regimen. Don't miss this insightful episode packed with actionable tips to enhance your well-being!

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/

Join Joe Cohen in the second episode of the DNA Deceptions series, where he takes a hard look at the world of DNA and genetic testing.

In this episode, Joe shares his unfiltered thoughts on 10x Genetics, explaining why he believes it’s one of the worst products in the genetic testing market.

From questionable marketing tactics to flawed science, this episode uncovers the truth behind the claims and sets the stage for a deeper exploration of the myths surrounding genetic testing.

A must-listen for anyone seeking clarity in the confusing world of DNA-based health solutions!

In the first episode of the DNA Deception series, Joe Cohen takes a critical look at 3x4 Genetics and their functional approach to DNA testing. With an emphasis on the science and practical applications, Joe explains why this method often fails to meet expectations. Whether you're exploring DNA-based health solutions or simply curious about genetic testing, this episode offers valuable insights into the promises and pitfalls of functional genetics.

In this special "Best of Season 7" episode, we’re revisiting the most impactful, inspiring, and thought-provoking moments from our standout interviews this season. From groundbreaking health hacks and personal growth strategies to expert insights on optimizing your life, these are the clips that sparked the biggest conversations. Whether you're a long-time listener or new to the show, this episode is packed with must-hear wisdom from our incredible guests. Tune in for a quick recap of what made Season 7 unforgettable!

- Check out SelfDecode: https://selfdecode.com/

- Join Joe’s online community: https://thejoecohenshow.com/