High Performance Longevity

#184 Control Your Genetics: A Deep Dive Into Epigenetic Testing, Biological Age Clocks, Longevity Protocols, Therapies & Supplementation | Hannah Went @TruDiagnostic


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What if aging was optional? Or what if you actually have control over your genetics or genetic dispositions to diseases and the like?

In today’s episode, Hannah Went, TruDiagnostic, explore the powers of epigenetics in optimizing health & longevity. Find out about biological age clocks, the role of fat-soluble vitamins, & how lifestyle changes outperform pharmaceuticals in slowing aging. Hannah discusses tools like the True Health Report, methylation risk scores, and advanced tracking technologies to help you take control of your health journey. Learn about all this and more in today’s episode on Everything Epigenetics

Meet our guest

Hannah Went is a biology graduate from the University of Kentucky with a passion for longevity & disruptive technologies. She has a background in cell signaling research & served as Director of Research & Content for the International Peptide Society. In 2020, she founded TruDiagnostic, a company specializing in methylation-based diagnostics for life extension & preventive healthcare.

TruDiagnostic conducts extensive research, with over 30 clinical trials & one of the world’s largest private epigenetic health databases, testing over 35,000 patients. Hannah also created Everything Epigenetics to share insights on how DNA regulation impacts health.

Thank you to our partners
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  • The simple, guided, and actionable Outliyr Longevity Challenge helps you unlock your longevity potential, slow biological aging, and maximize your healthspan
  • Key takeaways
    • Your genetics, or DNA code, act as your hardware—unchanging & responsible for about 20% of your phenotypic outcomes
    • Epigenetics, the software of your genetics, control how genes are expressed. They are modifiable & account for 80% of health outcomes
    • Most genomic testing companies analyze the same genetic positions, but the key difference lies in interpretation
    • Epigenetics serve as a reliable biomarker, providing a running average of the past 3–6 months. They are stable yet adaptable
    • Blood labs can mislead if not done thoroughly, regularly, or analyzed for long-term trends. Variability in lab results can create the illusion of issues where none exist
    • Biological age clocks predict future health outcomes using biomarkers, but their value depends on how well they forecast specific diseases
    • Epigenetics integrate other aging factors, refined by how the algorithms are trained
    • Episode Highlights

      7:39 Understanding The Difference Between Genetics & Epigenetics

      15:03 Hierarchy of Diagnostics & Testing

      26:58 Advantages & Disadvantages of Data Tracking & Wearable Technology

      39:00 How to Personalize Your Health Using Data & Test Results

      48:00 The Best Longevity Protocols & Supplementation

      Links
      • Watch it on YouTube: https://youtu.be/bWEJ3DTYGHU
      • Full episode show notes: mindbodypeak.com/184
      • Connect with Nick on social media
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