Why is obesity so difficult to reverse even when people try to eat less? In this episode, Ethan sits down with Dr. Jason Fung, nephrologist and author of The Obesity Code and The Diabetes Code, to unpack the hormonal science behind weight gain, insulin resistance, and type 2 diabetes. They explore why the calorie model of weight loss often fails, how insulin drives fat storage, and why fasting can be a powerful metabolic tool. The conversation also touches on addiction, modern food environments, and sustainable approaches to health.

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SHOW HIGHLIGHTS

Introduction to Dr. Jason Fung

Type 1 vs Type 2 Diabetes

The Problem with the Calorie Model

Why Eating Less Often Fails

Hormones and Weight Gain

Insulin Resistance Explained

The Role of Fasting

Food Environment and Addiction

Why Processed Food Is So Powerful

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What if the way you are eating is directly shaping how you feel every single day?

In this episode, Ethan sits down with Rachael DeVaux to unpack the powerful connection between food, energy, cravings, and overall well being. They explore how ultra-processed foods impact mood and performance, and why many people fail to connect what they eat with how they feel. Rachael shares practical insight on shifting toward whole foods and how small nutritional changes can create noticeable differences in energy and stability.

Introducing Rachael DeVaux

Ethan’s Health Journey and Context

The Real Impact of Sugar Crashes

Why Energy Dips Keep Happening

Understanding Ultra-Processed Foods

Emotional Eating and Hidden Triggers

Building Awareness Around Daily Choices

Protein, Satiety, and Cravings

Sustainable Nutrition vs Diet Culture

Small Changes That Create Big Results

Long Term Habits That Actually Stick

Final Thoughts on Taking Control of Your Health

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Are carbohydrates really the enemy of weight loss? In this episode of the American Glutton podcast, Ethan sits down with Paige to tackle the intense debate surrounding low-carb and no-carb diets.

Ethan passionately argues against moralizing food and blaming a single macronutrient for weight gain. Instead of relying on unsustainable quick fixes, he emphasizes the importance of looking at total energy intake, emotional triggers, and foundational health pillars like quality sleep. Tune in to hear why extreme diets often fail and how to build a realistic approach for long-term success.

SHOW HIGHLIGHTS

Introduction and Weather

The Carb Debate: Low Carb vs. No Carb

The Reality of Caloric Deficits

Good Carbs, Bad Carbs, and Moralizing Food

Quick Fixes vs. Real Examinations

Shifting Mindsets and Sustainable Strategies

Closing Thoughts

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What does it really take to lose weight and keep it off for good? Ethan sits down with Dr. Holly Wyatt to unpack the science of metabolism, appetite regulation, and long term weight management. They explore why the body resists weight loss, how biology influences hunger, and what actually works beyond willpower. Dr. Wyatt shares practical insights drawn from decades of clinical research, offering clarity in a space full of confusion.

If you are serious about understanding sustainable fat loss, this conversation delivers real answers.

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SHOW HIGHLIGHTS

00:00:00 Welcome, Dr. Holly Wyatt

00:02:09 Ethan’s Weight Loss History

00:04:32 Appetite and Hormones Explained

00:12:31 The Reality of Weight Loss Maintenance

00:13:57 Extreme Calorie Restriction

00:16:37 Why We Regain Weight

00:18:28 Metabolism Adaptation

00:30:45 Set Point and Biological Defense

00:40:26 Exercise and Long-Term Health

00:50:34 Final Takeaways on Sustainable Fat Loss

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Is your favorite superfood actually a marketing success story? Ethan sits down with Natalie Alibrandi, a nutrition and food science expert who helps take products from concept to commercialization, to unpack how food trends are born. They explore the rise of kale, goji berries, cottage cheese hacks, and the powerful role marketing plays in shaping what we believe is healthy.

Natalie breaks down formulation, regulation, and the realities of the food industry, while Ethan digs into how consumer psychology drives demand.

00:00 Introduction and Natalie’s Background

05:42 How Food Trends Are Born

12:18 The Rise of Superfoods

18:47 Marketing vs Nutritional Reality

26:15 Product Formulation and Food Science

34:02 Consumer Psychology and Health Claims

42:30 The Business of Health Foods

50:11 Regulation, Labels, and Transparency

58:27 Social Media and Trend Acceleration

01:05:44 Final Thoughts and Takeaways

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How do you navigate the mental and physical hurdles of long term weight maintenance? In this episode of American Glutton, Ethan Suplee sits down with host Paige to answer listener questions on everything from breaking through stubborn plateaus to the realities of life after GLP 1 medications.

Ethan shares his personal strategies for managing intense food cravings with healthy hacks and explains why he prioritizes sleep as the essential foundation for any successful health journey. He also offers advice on using a diet break to reset your metabolism when progress stalls.

• Swapping to Egg Whites
• Calculating Caloric Maintenance
• The Work of Weight Maintenance
• GLP 1s and Regaining Weight
• Navigating Cravings and Food Hacks
• Prioritizing Sleep Over the Gym
• Using Diet Breaks to Reset

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What happens when you come face to face with death and are forced to make a choice?

Ethan sits down with Jaimie Alexander to unpack a raw, deeply personal story about sobriety, self-worth, and survival. Jaimie opens up about being a highly functioning alcoholic, the quiet rationalizations that kept her drinking, and the medical crisis that nearly took her life. What followed was a moment of clarity that changed everything and led to a commitment she could not ignore. This conversation is honest, emotional, and unfiltered, exploring pain, meaning, and the power of choosing to stay.

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SHOW HIGHLIGHTS

00:00 Wired Headphones and Small Talk

00:26 Jaimie’s Journey to Sobriety

01:31 High-Functioning Alcoholism Explained

03:13 The Illusion of Control

05:54 Drinking as Medication

06:07 The Question of Rock Bottom

09:03 Dating, Anxiety, and Drinking Before the Date

10:38 Accidentally Sober in a Snowstorm

15:10 Withdrawal, Denial, and Pushing Through

18:03 Severe Appendicitis and Ignored Pain

21:44 Facing Death in the Operating Room

25:54 “Do You Want to Stay or Go?”

29:43 Surviving Against the Odds

31:18 Choosing to Stay Alive

36:26 Power, Perspective, and Agency

41:30 Self-Kindness as a Practice

47:24 Meaning, Suffering, and Choice

53:57 Toxic Positivity vs Real Empathy

58:04 Sobriety, Growth, and Closing Reflections

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What if improving your physical health was never the real starting point?

In this episode, Ethan sits down with Dr. Tara Narula, cardiologist, journalist, and author, to explore the often ignored mental and emotional foundations of health. Together, they unpack the science of stress, the reality of mind body connection, and why resilience is not about toughness but about acceptance, flexibility, and daily practice.

Dr. Narula shares deeply personal stories from her medical training and clinical work, revealing how trauma, mindset, and social connection directly impact heart health and longevity. This conversation challenges quick fixes and offers a more honest blueprint for lasting change.

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What if weight gain, depression, and chronic illness are symptoms rather than the real problem?

Ethan sits down with Dr.Josh Redd, a functional medicine doctor, to explore why treating symptoms alone often fails. On this episode of American Glutton, Ethan Suplee and Dr. Redd dig into inflammation, metabolic dysfunction, mental health, and why personalized care matters more than one-size-fits-all diets or pills. They discuss real patient stories, overlooked root causes, and what true healing can look like.

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SHOW HIGHLIGHTS

00:00 - What Functional Medicine Really Means

04:10 - Treating Root Causes Instead of Symptoms

09:05 - Why One Size Fits All Diets Fail

14:40 - When Weight Is a Symptom, Not the Problem

20:30 - Brain Inflammation and Mental Health

27:15 - The Emotional Cost of Chronic Illness

32:40 - A Child’s Drawing That Changed Everything

38:20 - Why Patients Feel “Crazy” When Labs Are “Normal”

45:10 - Food, Inflammation, and Modern Lifestyles

52:35 - Why Healing Requires Education, Not Just Treatment

59:40 - What Real Health Transformation Looks Like

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What does it really mean to start over without punishing yourself? Ethan Suplee sits down with Paige Dorian to unpack the emotional and psychological weight of restarting, whether it is after the holidays, a setback, or yet another failed plan. Ethan speaks candidly about crash diets, the illusion of quick fixes, and why weight loss is something to manage, not cure.

Together, they explore sustainable habits, realistic readiness, and the importance of support and accountability. This conversation is a grounded reminder that real change comes from compassion, not extremes.

SHOW HIGHLIGHTS

00:00 Starting Over and January Resets

02:05 The Gloom of Restarting

06:38 Why Crash Diets Fail

09:31 Sustainable Change vs Quick Fixes

12:17 Mindless Eating and Awareness

14:57 Exercise and Unrealistic Expectations

19:36 The Readiness Formula

24:03 Weight Loss vs Life Improvement

26:01 Accountability and Support Systems

30:55 Managing Weight for Life

36:44 Broadening the Goal Beyond Weight

42:19 Compassion, Guardrails, and Self Control

48:00 New Year Perspective

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