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What if the fatigue, brain fog, joint pain, or mysterious symptoms you've been chasing for years weren't caused by stress, aging, or burnout—but by a tick bite you never even noticed? Lyme disease is one of the most misunderstood illnesses in medicine. But Lyme is rarely just one infection—it's often part of a much bigger picture involving co-infections, immune dysfunction, inflammation, gut health, and environmental triggers.
In today's episode, I walk through a functional medicine approach to Lyme disease and tick-borne illness, including:
Lyme disease isn't always just an infection—it's often a whole-body disruption. By addressing the underlying drivers of inflammation, immune dysfunction, gut health, and cellular resilience alongside the infection itself, you give your body the best chance to heal and recover.
Resources Mentioned:
(0:00) Introduction to Lyme disease, overview, and Dr. Hyman's experience
(4:13) Functional medicine's approach and comprehensive treatment strategies
(10:51) Innovative therapies for Lyme disease
(14:08) Managing die-off reactions and restoring gut health
(17:18) Supporting the immune and nervous systems; prevention strategies
(19:29) Future research, persistent symptoms, and conclusion
(21:15) Alzheimer's disease, neuroinflammation, and call to action
For decades, depression has often been described as the result of a chemical imbalance in the brain. But how strong is the evidence behind that idea? This episode explores one perspective on an area of medicine that continues to be actively debated and is intended to encourage thoughtful discussion—not to provide individualized medical advice.
View Show Notes From This Episode
https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link
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Join the 10-Day Detox to Reset Your Health
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Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
(0:00) The impact of the chemical imbalance theory and myths of mental illness
(2:02) Disclaimers and introduction of Joanna Moncrieff
(3:00) The serotonin myth, antidepressant use, and marketing of SSRIs
(16:12) Risks, side effects, and wrong-headed approaches to mental health
(21:00) Societal, biological, and lifestyle factors in mental health
(27:13) Commercial determinants of health
(30:49) The rise and implications of psychedelic treatments in psychiatry
(43:21) Drug-centered vs. disease-centered models in mental health
(45:40) The role of the brain and alternative approaches to treating depression
(50:00) Addressing severe depression and strategies for deprescribing antidepressants
(54:41) Reframing mental health narratives and future outlook
(57:09) Encouraging self-education, debate, and discussion in medicine
(59:23) Closing remarks, disclaimers, and gratitude to sponsors
Do you hit a wall every afternoon around 2 or 3 p.m.? If your energy disappears, your brain gets foggy, and you need caffeine or sugar just to finish the day, it isn't a lack of willpower—it's a sign that something deeper is driving your energy crash. In this episode, I explain the three biggest drivers of the afternoon slump and the simple changes that can help you maintain steady energy all day long.
In today's episode, I discuss:
That afternoon crash isn't something you have to accept as part of modern life. When you stabilize your blood sugar, support your body's natural rhythms, and reduce chronic stress, your energy becomes more consistent, your focus improves, and you stop relying on caffeine and willpower just to make it through the day.
Resources Mentioned:
(0:00) Understanding the afternoon crash and blood sugar's role in energy
(4:36) Importance of circadian rhythm
(8:06) Environmental toxins and health
(9:36) Impact of stress on energy and caffeine use
(12:55) Rapid fire Q&A
(15:08) Key takeaways for steady energy
We all experience stress. The real challenge isn't stress itself—it's whether we recover from it. Over time, chronic stress can quietly affect everything from inflammation and metabolism to sleep, digestion, and healthy aging.
View Show Notes From This Episode
https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link
Get Free Weekly Health Tips from Dr. Hyman
https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
(0:00) Introduction to HRV
(3:43) Introduction to Salim and his HRV expertise
(4:18) What is HRV and how is it measured
(5:32) Chronic stress, stress regulation, and sovereignty
(9:52) Why HRV is an important health metric
(20:31) Deeper dive into HRV as a health indicator
(25:43) Salim's HRV coaching, website, and personal journey
(28:49) Salim’s framework and steps for improving HRV
(30:07) The role of sleep and hormetic stress in HRV
(33:12) Tools and tracking for HRV measurement
(37:22) The art framework and five pathways for HRV
(38:17) Salim’s injury, reframing, and HRV improvement
(46:22) Viktor Frankl, intentionality, and alignment
(51:46) Community and its role in health and HRV
(55:02) Practical steps for building community and emotional regulation
(58:18) Emotional processing, elite athletes, and HRV performance
(1:00:35) Sovereignty, compassion, and daily nervous system practices
(1:03:18) Awareness, parasympathetic activation, and reframing HRV
(1:05:01) Closing remarks, social media, and gratitude
(1:05:51) Disclaimer and sponsor acknowledgments
Histamine isn't just about seasonal allergies or a runny nose. It influences your brain, gut, hormones, immune system, and nervous system—and when your body can't regulate it properly, it can show up as everything from anxiety and migraines to insomnia, digestive issues, skin rashes, and brain fog. In this episode, I explain why histamine overload happens, how it relates to Mast Cell Activation Syndrome (MCAS), and what a root-cause approach looks like for calming an overactive immune system.
For decades, we've thought about conditions like Alzheimer's disease, depression, and Parkinson's disease as disorders of the brain. But what if that's only part of the story?
https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link
Get Free Weekly Health Tips from Dr. Hyman
https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
(0:00) Understanding brain dysfunction, inflammation, and lifestyle interventions
(0:21) Heavy metals, toxins, and Parkinson's disease
(3:30) Introduction to the summer series on brain health
(4:02) The MIND diet, precision nutrition, and brain-healthy fats
(9:06) Vitamins, supplements, and caloric intake for cognitive health
(11:23) Vitamin D, B complex, and reversing mild cognitive impairment
(14:05) Additional supplements and intensive lifestyle interventions
(17:18) Importance of magnesium and metabolic health
(18:24) Multimodal treatments, hormone replacement therapy, and individualized care
(26:49) Biopsychosocial factors, stress, and the gut-brain connection
(32:30) Inflammation, energy dysregulation, and metabolism in brain health
(42:33) Parkinson's disease: causes, history, and environmental factors
(46:02) Leaky brain, blood-brain barrier, and Parkinson's as a whole-body disease
(49:00) Closing remarks, disclaimer, and gratitude to sponsors
You've cleaned up your diet. You're taking the supplements. You're exercising, sleeping more, and doing everything "right." So why do you still feel exhausted, inflamed, anxious, or stuck? In this encore episode—one of the most impactful Office Hours conversations we've shared—I explore a question that could change the way you think about healing: What if your nervous system is the missing piece? When your body doesn't feel safe, it prioritizes survival over repair, affecting everything from your metabolism and hormones to your gut, immune system, and brain.
In today's episode, I break down:
Healing isn't just about finding the right supplement or following the perfect diet. It's about creating an environment where your body feels safe enough to repair itself. When you begin working with your nervous system instead of against it, everything else—from your energy and metabolism to your mood and resilience—can start to change.
Check out my full conversation with Dr. Scott Sherr HERE.
Have a question you’d love answered on Office Hours? Submit it here
Resources Mentioned:
As part of our summer series, we're revisiting some of the most important conversations we've had on the topics that matter most to our health. And few are more important than heart disease.
https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link
Get Free Weekly Health Tips from Dr. Hyman
https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
(0:00) The persistence of heart disease and the low-fat diet hypothesis
(0:32) Preventing heart disease through diet, lifestyle, and simple behaviors
(2:19) Revisiting key conversations on heart disease
(3:44) Beyond cholesterol: deeper drivers and risk factors
(7:18) Typical workup, treatments, and advances in cholesterol testing
(17:48) Metabolic health, hormonal, and inflammatory factors in heart disease
(29:37) Advances in cardiovascular diagnostics and AI
(31:31) Impact of lifestyle and new pharmacological treatments
(36:55) Statins, side effects, and lipoprotein fractionation
(40:13) The role of AI, new diagnostics, and Dr. Topol's journey
(43:19) Rethinking treatment: diet, industry influence, and the low-fat craze
(45:28) Saturated fat, cholesterol, and revisiting the evidence
(48:00) Cholesterol in heart disease risk and systematic drug review
(52:31) Insulin resistance, cholesterol’s role, and mortality
(58:31) Challenges in changing medical dogma
(1:00:31) Closing remarks and call to action
High cholesterol has been treated as the main cause of heart disease for decades. But over the years, I've changed my mind. Today, I believe cholesterol is only part of the story, and that inflammation, insulin resistance, and metabolic health are often the real drivers of cardiovascular disease. In this encore episode, I'm revisiting one of my most talked-about Office Hours conversations to share how my thinking has evolved and why understanding the root cause of heart disease can completely change the way you approach prevention.
In today's episode, I discuss:
Heart disease isn't simply a cholesterol problem—it's often a metabolic and inflammatory problem. When you understand what's really driving your risk, you can stop chasing a single number and start addressing the underlying biology that supports lifelong cardiovascular health.
Track your metabolic and cardiovascular health biomarkers: functionhealth.com/mark for 160+ lab tests at just $365/year. Use code MARK2026 for $50 off.
Have a question you'd love answered on Office Hours? Submit it here'
(0:00) The cholesterol and heart disease paradox; introduction and overview of cholesterol, inflammation, and metabolic health
(1:11) Sponsor: Function Health
(1:41) Traditional views vs. new science on cholesterol, inflammation, and heart disease
(4:52) Inflammation and sugar as key factors in heart disease
(8:41) Advanced markers: ApoB, lipoprotein fractionation, and comprehensive testing
(13:57) Causes of inflammation and holistic heart disease prevention
(19:35) Metabolic health risks, new technologies, and personalized interventions
(22:35) Diet, exercise, lifestyle, and supplements for heart and metabolic health
(25:03) Understanding heart disease beyond cholesterol
(25:37) Sponsor: Brain Shaping Academy
(26:33) Community engagement, sharing, and final thoughts
(28:07) Sponsor acknowledgments and closing remarks
Most health issues don't appear overnight. Long before a diagnosis is made, the body often provides subtle clues that something needs closer attention.
On this episode of The Dr. Hyman Show, I talk with double board-certified fertility physician Dr. Natalie Crawford about her new book, The Fertility Formula, and why fertility and hormone health can reveal far more about your health than many people realize.
We discuss:
Why the menstrual cycle may be one of the clearest indicators of overall health
How sleep, stress, and insulin resistance may be affecting your hormones
The overlooked symptoms that may signal deeper dysfunction
What many women get wrong about PCOS and hormone health
Practical strategies to support fertility, reduce inflammation, and improve long-term health
Health challenges don't begin when symptoms become impossible to ignore. They often start years earlier. Being able to recognize those signals is one of the most effective ways to take a proactive approach to your health.
Looking for a place to start? My 10-Day Detox is designed to help reduce inflammation, reset your metabolism, and build a stronger foundation for long-term health.
View Show Notes From This Episode
Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health - https://drhyman.com/products/brainshaping?utm_source=dr_hyman_show&utm_medium=newsletter&utm_campaign=may_27&utm_content=link
Get Free Weekly Health Tips from Dr. Hyman
https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive
This episode is brought to you by BIOptimizers, Paleovalley, Perfect Amino, Rho, Sunlighten, and Pique.
Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%.
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(0:00) Infertility and fertility as indicators of overall health
(3:10) Welcome Natalie Crawford and reframing fertility as health optimization
(5:21) Access to fertility data, proactive health, and reproductive well-being
(7:25) Menstrual cycle, hormonal communication, and ovulatory dysfunction
(14:39) Inflammation's role in reproductive health
(19:11) Reproductive health relevance beyond fertility and early warning signs
(21:13) Medical training, coping mechanisms, and personal journey with celiac disease
(23:48) Self-advocacy and higher infertility rates among female physicians
(25:03) Personal experience with recurrent pregnancy loss
(27:09) Inflammation, genetics, family history, and patient-centric care
(35:38) Reducing inflammation, mitochondrial health, and top health recommendations
(38:28) Sleep, stress, and their effects on fertility
(47:25) Insulin resistance, diet optimization, and fertility
(55:37) Environmental toxins, plastics, and hormone health
(1:00:09) Unscented vs. fragrance-free products and toxin reduction
(1:01:18) Fertility, aging, ovarian health, and AMH testing
(1:07:38) Male fertility, sperm health, and testosterone
(1:09:10) Resources for reproductive health and personalized care
(1:10:16) Outro and sponsor acknowledgment
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