In a world where healthcare often focuses on treating illness rather than promoting wellness, what does it really take to live a healthy, vibrant life?

You can catch our full conversation on YouTube or listen wherever you get your podcasts.

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Relationships have the power to change lives in ways both visible and hidden. Deep, supportive bonds can quiet inflammation in the body, protect against disease, and anchor people through decades of triumphs and trials. Communities that come together—whether in small groups at a church or around a shared health goal—often achieve far more than individuals working alone, sometimes transforming their health on a massive scale. Lifelong friends celebrate each other’s victories without jealousy, weather hardship side by side, and dare to speak difficult truths even at the risk of the relationship. Yet, many remain in unfulfilling connections out of fear of loneliness, forgetting that genuine, vulnerable connection is not just emotionally nourishing—it is essential to human health and resilience.

In this episode, I talk with Simon Sinek, Esther Perel, and Angelika Alana about how relationships are vital not just for emotional health, but for physical wellbeing and can be a great source of growth and healing.

Simon is a spark that ignites passion and ideas. He envisions a world where people wake up inspired, feel safe, and end their day fulfilled. As an unshakeable optimist and trained ethnographer, Simon is fascinated by people and organizations that make a lasting impact. He has discovered remarkable patterns in how they think, act, and communicate, revealing how people perform at their best. Simon is widely known for his TED Talk on "WHY" and his viral video on millennials in the workplace. Through bestselling books like Start with WHY and his podcast A Bit of Optimism, he continues to inspire. Founder of The Optimism Company and Optimism Press, Simon shares innovative views on leadership, attracting international attention. He also works with the U.S. government, the RAND Corporation, and in 2021, founded The Curve to reform modern policing, advancing justice with dignity, equity, and fairness.

Psychotherapist and New York Times bestselling author Esther Perel is recognized as one of today’s most insightful and original voices on modern relationships. Fluent in nine languages, she helms a therapy practice in New York City and serves as an organizational consultant for Fortune 500 companies around the world. Her celebrated TED Talks have garnered more than 30 million views and her bestselling books, Mating in Captivity and The State of Affairs, are global phenomena translated into nearly 30 languages. Esther is also an executive producer and host of the popular podcasts Where Should We Begin? and How’s Work? Her latest project is Where Should We Begin - A Game of Stories with Esther Perel.

Angelika Alana is the founder and CEO of the Somatic Healing Institute. She has been featured in Vanity Fair, Well+Good, and Modern Luxury. She certifies coaches and facilitators in her transformational body-based healing method. She has traveled and studied extensively in Indonesia, Brazil, Australia, and the UK, and is a massive foodie with her husband Patrick Drake, co-founder of Hello Fresh.

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Full-length episodes can be found here:

Simon Sinek on the Power of Relationships for Longevity

How To Have Successful Relationships

How To Move From Toxic Relationships And Sex To Healing Relationships And Sex

With so much conflicting health advice online, it’s no wonder people feel overwhelmed by food choices. Is saturated fat really the enemy? Are seed oils as harmful as some headlines claim? And how do we know what’s actually true? 

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Medicine stands at the threshold of a new era, where artificial intelligence and systems biology are working hand in hand to make care more personal, predictive, and precise than ever before.

AI is already improving diagnostic accuracy, automating administrative tasks, and uncovering patterns in data—like retinal scans or genomics—that humans often miss.

Rather than replacing doctors, AI enhances their ability to deliver more informed, precise, and efficient care. At the same time, individuals are gaining tools—from at-home diagnostics to wearable biosensors—that empower them to track and optimize their own health.

This shift marks a move from reactive, disease-centered care to a proactive, data-driven model of scientific wellness.

In this episode, I talk with Dr. Eric Topol, Dr. Nathan Price, Dr. Leroy Hood, Dr. Vijay Pande, and Daisy Wolf about how artificial intelligence, personalized data, and wearable technology are converging to radically transform medicine.

Dr. Eric Topol is Executive Vice President of Scripps Research and founder/director of its Translational Institute, recognized as one of the top 10 most cited researchers in medicine with over 1,300 publications. A cardiologist and author of several bestselling books on the future of medicine, he leads major NIH grants in precision medicine and shares cutting-edge biomedical insights through his Ground Truths newsletter and podcast.

Dr. Nathan Price is Chief Scientific Officer at Thorne HealthTech, author of The Age of Scientific Wellness, and a National Academy of Medicine Emerging Leader. He also serves on the Board on Life Sciences for the National Academies and is Affiliate Faculty in Bioengineering and Computer Science at the University of Washington.

Dr. Leroy Hood is CEO and founder of Phenome Health, leading the Human Phenome Initiative to sequence and track the health of one million people over 10 years. A pioneer in systems biology and co-founder of 17 biotech companies, he is a recipient of the Lasker Prize, Kyoto Prize, and National Medal of Science.

Dr. Vijay Pande is a General Partner at Andreessen Horowitz and founder of a16z Bio + Health, managing over $3 billion in life sciences and healthcare investments at the intersection of biology and AI. An Adjunct Professor at Stanford, he is known for his work in computational science, earning honors like the DeLano Prize and a Guinness World Record for Folding@Home.

Daisy Wolf is an investing partner at Andreessen Horowitz, specializing in healthcare AI, consumer health, and healthcare-fintech innovation. She previously worked at Meta and in various startups, holds a JD from Yale Law, an MBA from Stanford, and a BA from Yale, and is based in New York City.

This episode is brought to you by BIOptimizers.

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Full-length episodes can be found here:

Can AI Fix Our Health and Our Healthcare System?

The Next Revolution In Medicine: Scientific Wellness, AI And Disease Reversal

The Future of Healthcare: The Role of AI and Technology

This special bonus episode features Dr. Todd LePine from the UltraWellness Center, diving into how functional medicine can help reverse fatty liver disease—an often-overlooked condition that’s quietly affecting millions. While conventional care may miss early warning signs or focus solely on medication, Dr. LePine and I take a deeper look at the root causes.

Our healthcare system is broken—and it’s not by accident. On this episode of The Dr. Hyman Show, I’m joined by Brigham Buhler, a former pharmaceutical rep turned healthcare entrepreneur, to explore how misaligned incentives across pharma, insurance, and government are undermining patient care. 

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Social media platforms are designed to hijack our brain’s reward system, keeping us hooked through endless dopamine hits. This constant stimulation fragments our attention, reshapes our behavior, and can lead to burnout, anxiety, and even addiction—especially in developing brains. The more we scroll, the more we crave quick hits of novelty, making it harder to tolerate boredom or engage in deeper, more meaningful tasks. And while adults may struggle, kids are even more vulnerable, facing emotional dysregulation and long-term brain changes. The good news? Awareness is the first step toward reclaiming agency and creating healthier boundaries in a world built for distraction.

Jonathan Haidt is a social psychologist, bestselling author, and professor at NYU’s Stern School of Business. His research focuses on the moral foundations of culture and politics, exploring why good people are divided by religion, ideology, and values. He is the author of The Happiness Hypothesis, The Righteous Mind, and The Coddling of the American Mind (co-authored with Greg Lukianoff), and has given four widely viewed TED talks. Haidt is also a co-founder of Heterodox Academy, the Constructive Dialogue Institute, and Ethical Systems—organizations that promote viewpoint diversity, constructive disagreement, and ethical leadership. Since 2018, he has turned his attention to the mental health crisis among teens and the role of social media in political polarization. His latest book, The Anxious Generation: How the Great Rewiring of Childhood is Causing an Epidemic of Mental Illness, was published in 2024. In 2019, he was inducted into the American Academy of Arts and Sciences.

Cal Newport is an associate professor of computer science at Georgetown University. In addition to researching cutting-edge technology, he also writes about the impact of these innovations on our culture. Newport is the author of six books, including Slow Productivity, Digital Minimalism, and Deep Work. His work has been featured in many publications, including the New York Times, the Wall Street Journal, and the Economist, and he has been writing essays for his personal website (CalNewport.com) for over a decade. He has never had a social media account.

Tobias Rose-Stockwell is a writer, designer, and media researcher whose work has been featured in major outlets such as The Atlantic, WIRED, NPR, the BBC, CNN, and many others. His research has been cited in the adoption of key interventions to reduce toxicity and polarization within leading tech platforms. He previously led humanitarian projects in Southeast Asia focused on civil war reconstruction efforts, work for which he was honored with an award from the 14th Dalai Lama. He lives in New York with his cat Waffles.

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Full-length episodes can be found here:

How to Protect Your Child’s Mental Health from the Dangers of Social Media

How Social Media May Be Ruining Your Life

How Social Media And AI Impacts Our Mental Health: Reclaiming Our Minds And Hearts And Healing A Divided World

On this episode of The Dr. Hyman Show, we’re exploring the emerging science of metabolic psychiatry. My guest, Dr. Iain Campbell, is a researcher at the University of Edinburgh and someone who has lived with bipolar disorder himself. He brings a rare dual perspective as both a scientist and a patient to this critical conversation. 

Catch our full conversation on YouTube here - https://youtu.be/YCcZb2H2Ceg

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This episode is brought to you by Sunlighten, Paleovalley, AirDoctor and LMNT.

ADHD and other brain-based conditions such as depression, autism, and even schizophrenia are increasingly understood as inflammatory disorders of the brain—deeply rooted in the complex interplay between genetics, environment, and lifestyle. Many individuals go undiagnosed for years, internalizing harmful labels like “lazy” or “difficult,” until the weight of unaddressed symptoms finally becomes too much. But there is hope: Functional Medicine offers a radically different approach by uncovering and addressing root causes such as nutritional deficiencies, gut microbiome imbalances, food sensitivities, toxin exposures, and lifestyle factors. Stories of transformation emerge when these root drivers are corrected—children once labeled disruptive begin to thrive, adults regain focus and emotional balance, and families find relief. This emerging paradigm offers not just symptom management but the possibility of genuine healing through personalized, whole-body care.

In this episode, I discuss, along with Dr. George Papanicolaou and Dr. Jaquel Patterson, how ADHD and other mental health challenges are often rooted in inflammation and imbalances in the body—and how addressing diet, lifestyle, and root causes can lead to real healing.

Dr. Papanicolaou is a graduate of the Philadelphia College of Osteopathic Medicine and is Board Certified in Family Medicine from Abington Memorial Hospital. Over time as the healthcare system made it harder for patients to receive personal care, Dr. Papanicolaou decided a change was needed. He began training in Functional Medicine through the Institute of Functional Medicine. In 2015, he established Cornerstone Personal Health—a practice dedicated entirely to Functional Medicine. In August 2017, I invited Dr. Papanicolaou to join The UltraWellness Center and we’ve been successfully helping people together ever since.

Dr. Jaquel Patterson is a nationally recognized naturopathic physician, success coach, three-time Amazon bestselling author, and Forbes contributor. She owns a successful medical practice, Fairfield Family Health in Connecticut, and brings over 16 years of clinical experience, specializing in Lyme disease, autoimmune conditions, integrative psychiatry, and environmental medicine. A sought-after speaker, Dr. Patterson has been featured in USA Today, New York Magazine, and Forbes, and on CBS, Fox, NBC, and ABC. She’s the past president of the American Association of Naturopathic Physicians and currently serves on the board of the American Academy of Environmental Medicine. Certified by the Institute for Functional Medicine (IFM), she’s also completed a fellowship in functional medicine with a focus on psychiatry and ADD/ADHD. In addition to her naturopathic medical degree, Dr. Patterson holds an MBA in Healthcare Management from Quinnipiac University and an undergraduate degree from Cornell University.

This episode is brought to you by BIOptimizers.

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Full-length episodes can be found here:
Why ADHD Is Not A Psychiatric Disorder Or Brain Disease

What’s Fueling Our Mental Health Crisis and How Can We Fix it?

7 Strategies To Address ADHD

On this episode of The Doctor Hyman Show, I sit down with Dr. Eric Topol—renowned cardiologist, geneticist, and founder of the Scripps Research Translational Institute—to talk about the future of disease prevention. From AI diagnostics to genetic risk scoring, we explore the tools that could help stop Alzheimer’s and other chronic diseases before they start.

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This episode is brought to you by Seed, Pique, fatty15 and AirDoctor.