Ultra-processed foods (UPFs) are identified as the leading cause of preventable death globally. These foods are chemically altered, stripped of their natural structures, and filled with additives, sugars, unhealthy fats, and preservatives, resulting in products that offer little to no nutritional benefit while contributing significantly to chronic disease.

In this episode, I talk with Vani Hari and Dr. Shebani Sethi about why ultra-processed foods are not just a health risk—they are a public health crisis.

Vani Hari is the food activist behind FoodBabe.com, a NY Times best-selling author of 4 books, founder of the organic products brand Truvani, and was named one of the “Most Influential People on the Internet” by Time magazine. Hari’s viral testimony before the US Senate sparked a massive movement to stop American food companies from poisoning their own citizens with ingredients they don’t use in other countries. Hari founded Food Babe to spread information about what is really in the American food supply. She teaches people how to make the right purchasing decisions at the grocery store, how to live an organic lifestyle, and how to travel healthfully around the world. Vani has gathered hundreds of thousands of petitions to change the food system and influenced how major food giants like Kraft, Subway, Chipotle, Chick-fil-A, and Starbucks create their products, steering them towards more healthful policies.

Dr. Shebani Sethi is a double board-certified physician in Obesity Medicine and Psychiatry. She is the Founding Director of Stanford University’s Metabolic Psychiatry program and Silicon Valley Metabolic Psychiatry, a new center in the San Francisco Bay Area focused on optimizing brain health by integrating low carb nutrition, comprehensive psychiatric care, and treatment of obesity with associated metabolic disease. 

Full length episodes can be found here:

Why the Last Thing that Should Ever Eat is Ultra Processed Foods

How To Be A Food Activist In Your Own Kitchen

How Does Ultra-Processed Food Affect Our Mental Health?

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We all know sleep is important, but most of us don’t realize just how much it shapes our health—from metabolism and heart function to emotional well-being and even social connections. In this episode of The Dr. Hyman Show, I sit down with world-renowned sleep expert Matthew Walker, PhD, to uncover the science behind why sleep is one of the most powerful (and overlooked) tools for longevity.

In this fascinating conversation, we discuss:

If you’ve ever struggled with sleep—or just want to optimize your health—this is an episode you won’t want to miss.

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Highly processed vegetable oils, derived from seeds and beans, have become a dominant part of modern diets despite significant health concerns. Historical biases in nutrition science, influenced by the vegetable oil industry, have promoted these oils despite evidence from controlled studies showing negative health outcomes. These oils are unstable, prone to oxidation, and can create toxic byproducts, particularly when exposed to heat, contributing to inflammation and chronic diseases. Although they can lower LDL cholesterol, studies have shown that this reduction does not necessarily improve heart health and may increase risks for other conditions like cancer. In contrast, traditional fats like extra virgin olive oil and omega-3-rich foods offer more stability and health benefits, emphasizing the need for a balanced, minimally processed approach to dietary fats.

In this episode, I talk with Nina Teicholz and Max Lugavere to explore the health impacts of different types of fats and oils, debunking misconceptions around cooking with extra virgin olive oil and emphasizing the dangers of industrial vegetable oils.

Nina Teicholz is a science journalist and author of the New York Times bestseller, The Big Fat Surprise, which upended the conventional wisdom on dietary fat—especially saturated fat—and spurred a new conversation about whether these fats in fact cause heart disease. She is also the founder of the Nutrition Coalition, a non-profit working to ensure that government nutrition policy is transparent and evidence-based—work for which she’s been asked to testify before the U.S. Department of Agriculture and the Canadian Senate.

Max Lugavere is a health and science journalist and the author of the New York Times best-seller Genius Foods: Become Smarter, Happier, and More Productive While Protecting Your Brain for Life, now published in 10 languages around the globe. His sophomore book, also a best-seller, is called The Genius Life: Heal Your Mind, Strengthen Your Body, and Become Extraordinary and latest book Genius Kitchen. Max is the host of a #1 iTunes health and wellness podcast, called The Genius Life. Max appears regularly on The Dr. Oz Show, The Rachael Ray Show, and The Doctors. He has contributed to Medscape, Vice, Fast Company, CNN, and The Daily Beast, has been featured on NBC Nightly News, The Today Show, and in The New York Times and People Magazine. He is an internationally sought-after speaker and has given talks at South by Southwest, the New York Academy of Sciences, the Biohacker Summit in Stockholm, Sweden, and many others.

Full length episodes can be found here:

Is Vegetable Oil Good or Bad for You?

Nina Teicholz

The Best Diet for Your Brain

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Have you ever wondered if cholesterol-lowering statins are as effective as they claim? In this episode, Dr. Mark Hyman and Dr. Aseem Malhotra reveal the truth about these medications and the pharmaceutical industry’s influence on your health. Discover why lifestyle changes like diet and exercise can be more powerful than pills, and how misleading studies have shaped what we believe about heart health.

In this episode, we discuss:

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Our current food system is a national emergency. It’s intricately designed to confuse and mislead consumers, making healthy choices difficult and contributing to America’s chronic disease epidemic. In this episode, I sit down with Senator Cory Booker to delve into the systemic issues impacting our diet, food labeling, and the power of policy change. 

In this episode, we discuss:

Uncover the truth behind our food politics and discover how informed choices can lead to a healthier future. This conversation was hosted by Sixth and I in Washington, DC.

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Do you ever feel like the more meds you take, the worse you feel? The problem might lie in how our healthcare system operates. In this episode, I sit down with Dr. Marty Makary to tackle the alarming rise of colon cancer among young people, explore how our microbiome plays a crucial role in preventing chronic diseases, and discuss the unsettling influence of the pharmaceutical industry on medical practices. From the impact of antibiotics on children to the hidden dangers of over-medication, we unpack the urgent need for more transparency and a shift towards addressing the root causes of illness.

In this episode, we discuss:

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Heart disease, cancer, and stroke are the leading causes of death—and premature death at that—in the US. These diseases all have several risk factors in common, like smoking, physical inactivity, and poor diet, which policy often views simply as personal choices. We need to begin looking at disease prevention beyond individual decision-making.

In this podcast, I talk with Dr. Anand Parekh, Senator Bill Frist, and Dr. Dariush Mozaffarian on the need for government policymakers to address disease prevention.

Dr. Anand Parekh is the Bipartisan Policy Center’s chief medical advisor, providing clinical and public health expertise across the organization, particularly in the areas of aging, prevention, and global health. As a US Department of Health and Human Services deputy assistant secretary for health from 2008 to 2015, he developed and implemented national initiatives focused on prevention, wellness, and care management. He is the author of Prevention First: Policymaking for a Healthier America.

Senator Bill Frist is a heart and lung transplant surgeon and former US Senate majority leader. He led passage of the 2003 Medicare Modernization Act and the historic PEPFAR HIV/AIDS legislation that has saved millions of lives worldwide. As the founder and director of the Vanderbilt Multi-Organ Transplant Center, he has performed over 150 heart and lung transplants, authored over 100 peer-reviewed medical articles, and published seven books.

Dr. Dariush Mozaffarian is a cardiologist, Dean and Jean Mayer Professor at the Tufts Friedman School of Nutrition Science and Policy, and professor of medicine at Tufts Medical School. He has authored more than 400 scientific publications on dietary priorities for obesity, diabetes, and cardiovascular diseases and on evidence-based policy approaches to reduce these burdens in the US and globally. He has served in numerous advisory roles, including for the US and Canadian governments.⁣⁣ ⁣

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You’ve probably heard a lot about Robert F. Kennedy Jr., but beyond social media sound bites, do you really know where he stands on the issues shaping America’s health? Recorded last year when Kennedy was a presidential candidate, this episode of The Dr. Hyman Show provides a deep dive into his vision for improving the well-being of Americans. A vision Kennedy could put into action if confirmed as Secretary of Health and Human Services.

Kennedy is the founder of the Waterkeeper Alliance, the world’s largest clean water advocacy group, and served as its longtime chairman and attorney. He also founded the Children’s Health Defense and led efforts to address chronic disease and toxic exposures. As a litigator, he was part of the team that successfully prosecuted Monsanto for glyphosate’s link to cancer.

Tune in to explore Kennedy’s stance on tackling chronic disease, promoting regenerative farming, and improving the quality of the water we drink and the air we breathe.

In this episode, we discuss (audio version / Apple Subscriber version):

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Food has become a more complex part of our lives than ever before. Much of what we think is food is actually many ingredients disguised as food, with entirely different, often negative impacts on the human body. Sadly, this is a greater problem here in the US than in other parts of the world, thanks to the food industry, corrupt intentions, and broken policies. Today, I talk about all this and more with my guest Jason Karp, whose personal experience of nearly going blind due to a toxic lifestyle led him to discover a different way; he made it his mission to get “back to human.”

In this episode, we discuss:

We have a lot to do to shift our food system and eliminate harmful ingredients in the US, but there are ways to enact positive change starting today. We can all support a cleaner food industry and better health by voting with our dollar, purchasing real food, and getting involved in policy policy changes. I hope you’ll listen to this episode to learn more.

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What if the future of medicine isn’t about managing disease but erasing it? In this episode, I sit down with Dr. Darshan Shah to explore cutting-edge therapies like plasmapheresis and their potential to transform health and longevity. Together, we discuss how this innovative treatment reduces inflammation, supports recovery from long COVID, and improves aging biomarkers. Discover how personalized care and functional medicine could redefine how we approach healthspan and lifespan.

In this episode, we discuss:

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