The Dr. Hyman Show

By Dr. Mark HymanMedicine Health & Fitness Nutrition

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The Dr. Hyman Show episodes

May 18 Are You Secretly Dehydrated? Why a 1% Drop Kills Your Focus and Mood
Hydration affects far more than thirst. Even mild dehydration can impact your focus, memory, mood, energy, and overall brain performance—yet most people walk through the day without realizing they’re under-hydrated. The problem isn’t just not drinking enough water. It’s also caffeine overload, low electrolytes, processed foods, and inconsistent habits that quietly leave your brain and body struggling to keep up.
In today’s episode, we break down how hydration impacts brain health and what you can do to optimize it, including:
• Why even a 1–2% drop in hydration can lead to brain fog, fatigue, headaches, and reduced concentration
• The hidden role electrolytes play in energy, focus, and actually absorbing the water you drink
• How caffeine can quietly contribute to dehydration and create a cycle of fatigue and dependency
• Simple strategies to improve hydration—from morning water habits to eating more water-rich whole foods
Hydration isn’t just about drinking more water—it’s about helping your body and brain function the way they’re designed to. Small, consistent shifts can dramatically improve your energy, clarity, focus, and overall resilience.
Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year.
Want more on brain health? Sign up for the Brain Shaping Academy HERE.
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19 min
May 13 Women Are Not Small Men! Why Fitness Advice Is Failing Half the Population | Dr. Stacy Sims
Most health and fitness advice for women is based on research done in men. That’s something we need to rethink.
On this episode of The Dr. Hyman Show, I sit down with Dr. Stacy Sims, an exercise physiologist and leading researcher in women’s health. Her work has focused on how female physiology actually changes over time—and how training and nutrition need to change with it.
Watch the full conversation on YouTube, or listen wherever you get your podcasts.
We explore:
• Why eating less and doing more cardio can make fat loss harder
• What actually changes in your metabolism in your 30s and 40s
• How to train for strength—and why it matters for long-term health
• Why most workouts aren’t building muscle (and what to do instead)
• How to eat and time protein to support recovery, energy, and better sleep
A lot of the advice women have been given doesn’t account for how the body actually changes. Adjusting how you train and eat can make a meaningful difference in your energy, strength, and long-term health.
If you’re interested in learning more, Dr. Stacy Sims is offering my listeners 15% off her online courses with the code DRSTACYSIMS15OFF.
View Show Notes From This Episode
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Join the Hyman Hive for Expert Support and Real Results
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This episode is brought to you by Rho, Pique, Perfect Amino, Sunlighten, Korrus and Made In Cookware.
Head over to rhonutrition.com and use code HYMAN to get 20% off their entire product line.
Secure 20% off your order plus a free starter kit at piquelife.com/hyman.
Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order.
Visit sunlighten.com and use code HYMAN to save up to $1600 today!
Visit korrus.com/drhyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15.
Visit madeincookware.com and use code HYMAN10 for 10% off your order

(0:00) Women’s unique health needs, fitness, and nutrition mistakes
(0:56) Introduction of Dr. Stacy Sims
(3:34) Women’s health and fitness through life stages
(5:39) Navigating diet, exercise, and cognitive health for women
(24:00) Benefits and misconceptions of heavy weight lifting for women
(30:55) Understanding anovulatory cycles and high intensity interval training (HIIT)
(35:47) Reducing inflammation and proper high intensity exercise
(39:11) How to properly perform HIIT
(46:06) Overcoming gym intimidation and starting strength training
(50:12) Importance of community, support, and lifestyle on longevity
(55:01) Optimizing nutrition: circadian rhythm, time-restricted eating, and protein
(1:02:44) Post-exercise nutrition and fasted vs fed workouts
(1:08:01) Common nutrition mistakes for women
(1:12:17) Scheduling self-care and wellness meetings
(1:13:43) Quick fire questions on women’s health and fitness
(1:17:40) Benefits of creatine and favorite workout snacks
(1:18:23) Morning vs evening workouts and advice for younger self
(1:19:28) Where to learn more about Dr. Stacy Sims and Collective X Health
(1:20:20) Closing remarks, sharing, and social media
(1:21:15) Disclaimer, importance of healthcare practitioners, and sponsor gratitude

1 hr 24 min
May 11 The 5 Root Causes of Autoimmune Disease (And How to Start Healing)
Autoimmune disease is often treated as something random, lifelong, and out of your control. But what if it’s not your body malfunctioning—what if it’s your immune system responding exactly the way it’s designed to, to something it sees as a threat? When you understand what’s driving that response, everything changes.
Here’s what I cover in today’s episode:
• The 5 key drivers—food, toxins, gut health, infections, and stress—and how they disrupt the immune system
• Why diet is one of the most powerful levers for turning inflammation on or off every single day
• The connection between leaky gut, the microbiome, and immune dysfunction
• A practical, functional medicine framework to start reducing symptoms and addressing the condition at the root
Autoimmune disease isn’t random—it’s the result of cumulative inputs over time. When you begin to change those inputs, you can shift your biology, calm the immune system, and change the trajectory of your health.
Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year.
Join the 10-Day Detox: https://drhyman.com/pages/10-day-detox
Have a question you’d love answered on Office Hours? Submit it here

The waitlist is open**
Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health - Click here

(0:12) Introduction, Sponsor: Function Health, and Overview of Autoimmune Diseases
(1:38) Immune System, Causes, and Triggers of Autoimmune Disease
(3:45) Common Mistakes and Root Causes in Treating Autoimmune Disease
(5:26) Food, Diet, and Anti-Inflammatory Strategies
(11:47) Toxins, Gut Health, and the Microbiome
(17:32) Hidden Infections and Treating by Root Cause
(19:38) Stress and Other Triggers for Autoimmune Disease
(23:14) Sponsor: Brain Shaping Academy
(24:10) Audience Engagement, Sharing, and Subscription
(25:19) Disclaimer, Professional Advice, and Sponsor Gratitude

28 min
May 06 The Real Reason You Age (And How to Slow It Down) | Dr. Eric Verdin
We tend to think of heart disease, cancer, and Alzheimer’s as separate problems. But what if they all stem from the same underlying process?
On this episode of The Dr. Hyman Show, I sit down with Dr. Eric Verdin, whose research, including work on compounds like urolithin A, is helping reshape how we think about aging and long-term health. We explore why aging may be the biggest driver of chronic disease and what that means for how you approach your health.
Watch the full conversation on YouTube, or listen wherever you get your podcasts.
We unpack:
• How your immune system becomes both overactive and less effective over time
• What chronic inflammation is doing inside your body and how to start bringing it back into balance
• Why cellular energy and mitochondrial health are key to repair and recovery
• How your microbiome shapes inflammation, immunity, and long-term health
• The daily habits that impact longevity most and where people get it wrong
This conversation reflects a shift in how we think about health, moving beyond treating disease to understanding what’s driving it in the first place.
View Show Notes From This Episode
Get Free Weekly Health Tips from Dr. Hyman
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Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
This episode is brought to you by Timeline, Seed, BIOptimizers, BON CHARGE, Paleovalley and Big Bold Health.
Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79.
Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month.
Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%.
Head to boncharge.com/hyman and use code HYMAN for 15% off.
Head to paleovalley.com/hyman to save 15% off your first order today.
Go to bigboldhealth.com/drhyman and use code HYMAN15 to save 15% on your first order.

(0:00) Biological age vs. cholesterol in heart disease and chronic disease risk
(0:50) Introduction of Dr. Eric Verdin and his work
(1:23) Sponsor: Brain Shaping Academy
(1:51) Sponsor: Mitopure
(2:54) Sponsor: Seed
(3:48) Welcoming Dr. Eric Verdin and longevity framing
(5:42) The geoscience hypothesis and modifying age as a risk factor
(8:21) Early-stage interventions in aging and potential for life extension
(9:56) Longevity skepticism and practical steps for today
(11:20) Mitochondria, inflammation, and hallmarks of aging
(17:20) Mitochondrial DNA, inflammation, and immune system aging
(22:17) Innate vs. adaptive immunity and immune aging
(28:47) Strategies to combat immune aging
(33:07) Gut health, inflammation, and foundational elements of longevity medicine
(38:20) Social connections, sociogenomics, and cellular energy in aging
(46:29) Cellular repair systems and postbiotics
(50:33) Sponsor: Paleo Valley
(52:34) Sponsor: Big Bold Health
(53:23) Urolithin A, immune rejuvenation, and longevity interventions
(59:08) Longevity and functional medicine approaches
(1:02:27) Big data, AI, and the evolution of medicine
(1:04:26) Microbiome, diet, and gut health
(1:06:14) Measuring biological age and biological clocks
(1:09:37) Future of health monitoring and closing remarks

1 hr 13 min
May 04 6 Root Causes of Migraines (And How to Fix Them)
Migraines aren’t just headaches and if you’ve ever had one, you know how debilitating they can be. But they’re not random, and they’re not just genetic. Migraines are a signal that something deeper is out of balance in your body and if you only treat the symptoms, you miss the real opportunity to prevent them.
In this episode, I break down what’s really driving migraines, including:
• The root causes most people miss—from inflammation and blood sugar swings to hormones, gut health, and nutrient deficiencies
• Why migraines are a full-body neurological event, not just a head issue, and what that means for treatment
• How your cycle, stress levels, and nervous system can lower your threshold and make migraines more likely
• A functional medicine approach to prevention—simple shifts in diet, lifestyle, and nutrients that can reduce frequency and severity
Migraines don’t come out of nowhere—they happen when your body hits a threshold. When you lower the load and support your biology, you don’t just manage migraines—you can actually start to prevent them. To go deeper on this topic, check out my past episode with Dr. Todd LePine: https://youtu.be/hnmCIGNko64.
Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year.
Have a question you’d love answered on Office Hours? Submit it here
**The waitlist is open**
Sign up for Dr. Hyman’s Brainshaping Academy to learn how to nourish the biological systems that support your mental, emotional, and cognitive health Click here to sign up.
(0:12) Introduction and overview of migraines
(0:58) Understanding migraines and functional medicine approach
(2:08) Root causes of migraines: hormones, gut health, nutritional deficiencies, nervous system
(7:00) Practical steps for migraine prevention
(12:35) Regulating the nervous system
(14:44) Case study with Dr. Todd Lapine
(22:49) Introduction to Brain Shaping Academy and mental health

27 min
April 29 The Mental Health Crisis Starts in the Gut | Dr. William Li & Dr. Mark Hyman
It’s easy to think of mental health as something happening only in the brain. But more and more, we’re seeing how closely it’s tied to what’s going on in the gut.
Today, I’m joined again by Dr. William Li, a New York Times bestselling author. We discuss his latest book, Eat to Beat Your Diet, and how food, inflammation, and microbiome shape the way we think and feel.
Watch the full conversation on YouTube, or listen wherever you get your podcasts - https://youtu.be/rY0OE-1blL0
In this conversation we discuss:
• What if your anxiety or brain fog is actually a signal coming from your gut
• Why gut health may be the missing piece in how we think about mental health
• How everyday foods can either fuel inflammation or help calm your system
• The compounds in real food that quietly support memory, mood, and mental clarity
• Simple shifts that can help reset your system and support how you feel day to day
Mental health isn’t separate from the rest of the body. The more we understand that, the more it shifts where you look for answers.

If you’re looking for more support and community around this, the 10-Day Detox is designed to help reduce inflammation and support your body using real food.
View Show Notes From This Episode
Get Free Weekly Health Tips from Dr. Hyman
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Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
This episode is brought to you by Korrus, BIOptimizers, Seed, Maui Nui, Made In Cookware and Sunlighten.
Visit korrus.com/drhyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15.
Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%.
Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month.
Go to mauinuivenison.com/hyman to claim your free 6-pack of their Wild Axis Venison Jerky Sticks.
Visit madeincookware.com and use code HYMAN10 for 10% off your order.
Visit sunlighten.com and use code HYMAN to save up to $1600 today!

(0:00) Food as medicine, the flavorome, and the gut-brain connection
(3:20) Food, gut health, and mental health
(6:02) The flavorome’s impact on gut and brain health
(10:33) Importance of a balanced gut microbiome
(13:35) Feeding the microbiome with polyphenols
(21:19) Anti-inflammatory properties of ellagic acid and polyphenols
(26:05) Lactobacillus reuteri: benefits for wound healing and mental health
(30:12) Natural flavors, phytochemicals, and animal intelligence
(38:17) Inflammation, processed foods, and mental health
(44:12) Diet’s impact on gut health, symptoms, and benefits of cooking
(47:50) Polyphenols, brain health, and neurogenesis
(55:25) Ibogaine, brain regeneration, and personal experiences
(1:00:40) The future of brain and eye health
(1:02:28) Upcoming projects, professional advice, and gratitude
(1:05:45) Final thoughts, resources, and outro

1 hr 6 min
April 27 Feeding Kids Is Hard—Here’s What They Actually Need
Most parents are doing their best but the modern food environment is working against them. Between ultra-processed foods, constant marketing, and confusing nutrition advice, it’s easy to feel overwhelmed.
But what your child eats doesn’t just affect their growth—it shapes their brain, immune system, metabolism, and long-term health. In this episode, we break down what actually matters and how to approach it without perfection or guilt.
Here’s what every parent needs to know:
• The foundational nutrition principles that matter most for kids (and why blood sugar stability plays central role)
• Whether kids actually need supplements and the most common nutrient deficiencies to watch for
• How to strengthen your child’s immune system through food, gut health, sleep, and daily habits
• Practical strategies to reduce ultra-processed foods, handle picky eating, and support issues like eczema at the root
You don’t need to do everything perfectly to transform your child’s health. Small, consistent shifts—what’s on their plate, how they eat, and the environment you create—can shape their biology for decades to come.

Full Nora LaTorre Interivew - https://youtu.be/qWJ9LRAbXoY
Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year.
Have a question you’d love answered on Office Hours? Submit it here

(0:12) Introduction and overview of children's nutrition challenges
(0:33) Sponsor: Function Health
(1:01) Importance of nutrient density and sugar's impact on kids
(5:28) Five key nutritional anchors and supplements for kids
(10:34) Building a strong immune system and transitioning off processed foods
(17:02) Sponsor: Function Health
(18:06) Clean snack ideas and tackling school food challenges
(23:54) Diet's connection to eczema
(28:48) Rapid fire Q&A: seed oils, organics, and more
(33:48) Parental influence on children's health
(36:04) Closing thoughts and call to action

39 min
April 22 We Can Detect Cancer Years Earlier—So Why Aren’t We?
Most of medicine is built around snapshots. You feel something, you test for it, and by the time you find it, you’re already behind.
But what if the problem isn’t the test—it’s how we use it?
In this episode, I sit down with physicist and imaging pioneer Dr. Daniel Sodickson, Chief Medical Scientist at Function Health and author of The Future of Seeing. We break down why tools like MRI are shifting from one-time scans to something far more powerful: tracking your health over time.
Watch the full conversation on YouTube, or listen wherever you get your podcasts.
In this episode, we cover:
• Why waiting for symptoms puts you behind—and how to get ahead
• What an MRI can reveal about your body that bloodwork can’t
• How tracking your health over time helps you catch problems sooner
• Why having a baseline could change the way you make health decisions
• What it means to shift from reacting to disease to actually predicting it
When you stop looking at a single result and start looking at patterns, you can catch changes earlier, reduce false alarms, and better predict where your health is headed.
View Show Notes From This Episode
Get Free Weekly Health Tips from Dr. Hyman
https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
This episode is brought to you by BON CHARGE, Maui Nui, Sunlighten, Paleovalley, Fatty15 and BIOptimizers.
Head to boncharge.com/hyman and use code HYMAN for 15% off.
Go to mauinuivenison.com/hyman to claim your free 6-pack of their Wild Axis Venison Jerky Sticks.
Visit sunlighten.com and use code HYMAN to save up to $1600 today!
Head to paleovalley.com/hyman to save 15% off your first order today.
Head to fatty15.com/HYMAN today and use code HYMAN for 15% off your 90-day subscription Starter Kit.
Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%.

(0:00) Introduction and overview of modern medical imaging
(3:26) Discussion with Dr. Daniel K. Sodickson begins
(3:45) Full body MRIs: Benefits, risks, and the inspiration behind "The Future of Seeing"
(7:52) Extending senses and paradigm shifts in imaging technology
(14:55) Longitudinal imaging and its benefits
(19:17) Future of personalized health data and imaging technology
(23:54) Addressing information overload and reducing false positives through AI
(28:33) Cost, accessibility, and innovations in imaging techniques
(32:00) Vision for ubiquitous and continuous health scanning
(33:30) Imaging vs. blood work: Comprehensive health assessment
(35:29) Real-life examples and early detection through imaging
(39:27) Historical context and real-time health data collection
(41:46) Who should get baseline MRIs and scan frequency
(47:26) The everywhere scanner: Future implications and cancer detection
(52:35) Medical intelligence and transforming health monitoring
(57:47) Preventive measures, early detection, and course correction
(1:00:30) Medical intelligence labs and the future of healthcare
(1:03:32) Future of personal data-driven healthcare and closing remarks

1 hr 9 min
April 20 Can’t Fall or Stay Asleep? Your Sleep Questions Answered
Sleep is one of the most important and most overlooked drivers of your health. If you’re struggling to fall asleep, waking up at 2–4am, or getting a full night’s sleep but still feeling exhausted, your body is trying to tell you something.
Poor sleep isn’t just about habits, it’s a signal that key systems like your nervous system, blood sugar, hormones, or circadian rhythm are out of sync. In this episode, we break down what’s actually disrupting your sleep and how to fix it at the root.
Here’s what you’ll understand:
• Why sleep issues are rarely just one problem and how stress, blood sugar, and circadian rhythm all interact
• The real reasons you can’t fall asleep, wake up in the middle of the night, or feel tired despite 7–8 hours
• What actually helps (and what doesn’t)—from magnesium and melatonin to nervous system regulation
• The 5 core pillars of better sleep and the highest-impact changes you can start tonight
Sleep isn’t something you force, it’s something that happens when your body feels safe, balanced, and supported. When you address the root causes, better sleep becomes not just possible but predictable.
Visit ⁠functionhealth.com for 160+ lab tests at just $365 a year.
Have a question you’d love answered on Office Hours? Submit it here

(0:00) Sleep Quality vs. Duration and Introduction
(1:06) Common Causes of Poor Sleep
(6:53) Addressing Common Sleep Questions
(10:43) Evening Routines and Sleep Timing
(12:37) Metabolic, Hormonal, and Hidden Sleep Issues
(17:43) Recommendations for Deeper Sleep and Repair
(19:33) Supplements and Strategies for Better Sleep
(22:22) Key Takeaways and Quick Wins
(26:13) Conclusion, Listener Engagement, and Closing Remarks

30 min
April 15 Tired But Wired? The Hidden Loop Destroying Your Energy | Dr. Scott Sherr, MD
What if feeling better didn’t have to take months or years to figure out, but could start today?
On this episode of The Dr. Hyman Show, I sit down with Dr. Scott Sherr to talk about why so many people feel stuck in what he calls a “sympathetic spiral of doom.” Energy is low, recovery isn’t what it used to be, and there’s a constant sense of stress that doesn’t seem to resolve.
We walk through what’s actually happening beneath the surface, why it can be so hard to break out of that pattern once you’re in it, and how to start shifting your energy and recovery.
Watch the full conversation on YouTube, or listen wherever you get your podcasts.
In this episode, we discuss:
• Why you feel “tired but wired” and what it actually means for your body
• What’s keeping your energy low even when nothing obvious is wrong
• How stress from your life and environment builds up and keeps you stuck
• Why calming down doesn’t always work—and what to focus on instead
• How to start rebuilding your energy so your body can recover and adapt
We shouldn’t have to wait for something to go wrong to take action. The goal is to help your body function better so you can actually feel it day to day.
View Show Notes From This Episode
Get Free Weekly Health Tips from Dr. Hyman
https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Sign Up for Dr. Hyman’s Weekly Longevity Journal
https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast
Join the 10-Day Detox to Reset Your Health
https://drhyman.com/pages/10-day-detox
Join the Hyman Hive for Expert Support and Real Results
https://drhyman.com/pages/hyman-hive
This episode is brought to you by Perfect Amino, Korrus, Timeline, BON CHARGE, BIOptimizers and Pique.
Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order.
Visit korrus.com/drhyman for 15% off their newest product OIO Sphere with code HYMANSPHERE15.
Visit timeline.com/drhyman for 20% off a subscription on top of the new starting price of $79.
Head to boncharge.com/hyman and use code HYMAN for 15% off.
Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%.
Secure 20% off your order plus a free starter kit at piquelife.com/hyman.

(0:00) Introduction and guest Dr. Scott Scherer
(3:31) Understanding the sympathetic spiral of doom
(5:06) Symptoms and signs of sympathetic overdrive
(7:10) Sympathetic activation, mitochondrial function, and stress
(10:02) Mitochondria: their role and impact in the body
(12:31) Stress, metabolic dysfunction, and their effects
(17:43) Nervous system, mitochondria, and the cell danger response
(21:25) Survival, stress, and breaking the sympathetic spiral
(23:11) Contributors to stress: top-down and bottom-up
(25:56) Mitochondria, microbiome, and medication impacts
(29:38) Mitochondrial dysfunction and mental health
(32:19) Limitations of parasympathetic activation and addressing root causes
(36:46) How mitochondrial stress leads to fight-or-flight
(37:52) Steps to break the sympathetic spiral and support mitochondria
(42:41) Methylene blue: benefits, uses, and safety
(50:35) Methylene blue as an MAO inhibitor and for chronic infections
(57:17) Case studies, third-party testing, and Transcriptions' evolution
(1:02:36) Parasympathetic edge, recovery, and the GABA system
(1:07:44) GABA, supplements, and interventions for stress
(1:12:23) Addressing root causes and methylene blue usage
(1:17:29) Transcriptions products, sleep formula, and practitioner ecosystem
(1:19:49) OneBase Health, hyperbaric space, and final information

1 hr 22 min

About The Dr. Hyman Show

From the publisher's feed

Welcome to The Dr. Hyman Show, the podcast helping you take ownership of your health and reimagine what’s possible. Hosted by Dr. Mark Hyman—physician, bestselling author, and pioneer in functional medicine—this show explores the most pressing issues of our time: chronic disease, nutrition, mental health, food policy, prevention, and longevity.