The most played episodes among Podcast App listeners.

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   Number 1: Why More Women Are Choosing Transdermal Estradiol Over Oral

   If you've been talking with friends about hormone therapy or scrolling social media lately, you've probably heard someone say they switched from estrogen pills to a patch. It's not just a trend. Recent prescription data shows estrogen patch use continues to rise, and there's a good reason why. As we've learned more about menopause medicine, we've also learned that how estrogen gets into your body matters. In this episode, we break down: • Why estrogen patches have become increasingly popular in menopause care • How patches and pills work differently inside the body • What current research says about blood clot risk and cardiovascular health • Which women may benefit most from transdermal estrogen • The pros and cons of patches, pills, and estrogen gels • Common questions about absorption, dosing, and where to place your patch • How to decide which form of hormone therapy may be right for you The biggest takeaway? There isn't one "best" form of estrogen. The best choice depends on your health history, symptoms, lifestyle, and long term goals. As always, we break down the latest research so you can have informed conversations with your healthcare provider and make decisions that are right for you. Share this episode with a friend who's wondering whether an estrogen patch or pill is the better option. Estrogen Patch | Hormone Replacement Therapy | Menopause Treatment | Estradiol Patch | Menopause Symptoms | Women's Health | Hormone Therapy | Transdermal Estrogen #HumpDayHormones #Menopause #EstrogenPatch #HormoneReplacementTherapy #Estradiol #HormoneHealth #WomensHealth #MenopauseEducation #HealthyAging #TransdermalEstrogen

   August 05, 2026·44min
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   Number 2: How menopause care has evolved and how do we correct practices that remain stuck in the post-WHI era

   For more than 20 years, women have often heard one of two messages about hormone therapy: that it is dangerous and should be avoided, or that it is the answer to everything. Neither tells the full story. The research has changed, and menopause care has evolved. But not every headline on social media represents a true change in clinical practice. In this episode, we look at what has changed over the past 10 years, five years, and especially the past year, and what those changes actually mean for women navigating menopause. In this episode, we break down: • Why hormone therapy should no longer be treated as one medication with one universal risk profile • Why age, timing, dose, route, and type of hormone all matter when evaluating risks and benefits • How our understanding of genitourinary syndrome of menopause and vaginal estrogen has changed • What the evidence now says about vaginal estrogen for some breast cancer survivors • Where testosterone actually fits into evidence based menopause care • What has changed with compounded hormones, FDA warnings, and newer nonhormonal treatments for hot flashes • Why modern menopause care is moving away from rigid age based rules and toward individualized, risk based treatment We also talk about what hasn't changed. Hormone therapy is not a universal longevity drug, hormone levels alone should not diagnose perimenopause, systemic estrogen still requires appropriate endometrial protection when a woman has a uterus, and unexplained postmenopausal bleeding still needs evaluation. The biggest shift isn't that hormones are completely safe or completely dangerous. It's that we're finally moving beyond treating hormone therapy as one drug with one risk profile. The better question is: For this woman, for this indication, using this formulation, do the expected benefits outweigh the potential risks? That's what evidence based, patient centered menopause care should look like. Share this episode with a woman who has ever been told that hormone therapy is simply “good” or “bad.” Menopause Care | Hormone Replacement Therapy | Hormone Therapy Research | Menopause Treatment | Vaginal Estrogen | Testosterone Therapy | Women's Health | Evidence Based Menopause Care #HumpDayHormones #Menopause #HormoneReplacementTherapy #HormoneHealth #WomensHealth #MenopauseCare #VaginalEstrogen #TestosteroneTherapy #MenopauseResearch #HealthyAging

   August 26, 2026·55min
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   Number 3: I Can't Take Progesterone... Now What? What Is Up With Progesterone Intolerance

   Progesterone can be incredibly helpful for some women. It can support sleep, calm the nervous system, regulate bleeding, and play an important role in hormone therapy. But for some women, taking progesterone can bring on anxiety, depression, fatigue, dizziness, brain fog, bloating, or that frustrating feeling of simply not feeling like themselves. So what is actually happening? In Episode 82, we’re diving into progesterone intolerance, why some women can have such a different response to the same hormone, and what options exist when oral micronized progesterone simply doesn’t work for you. In this episode, we break down: • What progesterone intolerance actually is and how it differs from progestin intolerance • Why allopregnanolone and the GABA A receptor may play a role in how women respond to progesterone • Why some women tolerate their own natural progesterone but struggle with oral progesterone • How the timing, dose, and route of progesterone can change your experience • What other options may provide endometrial protection when oral progesterone isn't tolerated • Why progesterone creams may not provide adequate uterine protection • How options like an IUD, different progestins, or Duavee may fit into the conversation One of the biggest takeaways from this episode is that “I can’t tolerate progesterone” doesn’t mean the conversation is over. Your response to hormones is individual, and the goal is to find a safe, effective treatment plan that you can actually live with. If progesterone has ever made you feel worse instead of better, this is an episode you’ll want to hear. Share this with a woman who has ever wondered why progesterone makes her feel awful. Progesterone Intolerance | Progesterone Therapy | Hormone Replacement Therapy | Menopause Care | Micronized Progesterone | Hormone Health | Perimenopause | Women's Health #HumpDayHormones #Progesterone #ProgesteroneIntolerance #HormoneReplacementTherapy #Menopause #Perimenopause #HormoneHealth #WomensHealth #MicronizedProgesterone #MenopauseEducation

   August 19, 2026·56min
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   Number 4: Cortisol Chaos... Is It Sabotaging The Rest Of Your Hormones? With Special Guest Christa Jackson

   Are you exhausted but wired, waking at 3am, and wondering why your body feels out of sync?” “What if it is not just stress, but a full hormone and cortisol conversation your body is trying to have with you?” We are joined by Christa Jackson, APRN at Beyond Wellness, a clinician deeply rooted in personalized, root cause hormone care and formerly with Cornerstone OB GYN alongside Dr Kay Chandler. In this conversation, we dive into what she is seeing every day in women who feel overwhelmed, dismissed, and physically off balance. This episode unpacks what we are calling cortisol chaos, the intersection of chronic stress, hormone shifts, sleep disruption, and the realities of perimenopause that so many women are navigating at once. In this episode, we break down: • Why so many women feel anxious, fatigued, and unlike themselves during this stage of life • What cortisol actually does in the body and why it is essential, not the enemy • How chronic stress, sleep disruption, and blood sugar swings create a feedback loop • Why estrogen plays a major role in stress resilience and emotional stability • What changes in perimenopause that makes stress feel harder to recover from • How cortisol interacts with thyroid function and energy regulation • What clinicians are actually seeing in labs, symptoms, and real patient stories • Lifestyle and hormonal strategies that support recovery instead of burnout We also talk through what it looks like in real clinical practice when women feel terrible but are told everything looks normal, and how a different approach to hormones, sleep, and nervous system health can change everything. This conversation is about more than cortisol. It is about understanding what your body is adapting to, and why it is not failing you, it is responding. Share this with the woman who feels like her body is stuck in overdrive.

   May 20, 2026·1h 4min
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   Number 5: EP 34: Hormones and Breast Cancer

   This week on Hump Day Hormones, we’re leaning into one of the most emotionally charged and misunderstood topics in women’s health: hormones and breast cancer—especially the questions that arise after a diagnosis. For many women, the fear of breast cancer is the biggest barrier to considering hormone replacement therapy. Today, we’re setting the record straight by replacing fear with facts. We’re joined by a brilliant guest, Julie Turner, DNP, APRN, a high-risk breast specialist, hereditary cancer expert, and BRCA1 carrier, who brings both professional insight and deeply personal experience to this nuanced conversation. In this episode, we break down: -The science behind estrogen, progesterone, and breast cancer risk -What the data actually says about hormone use before and after breast cancer -Common myths born out of misinterpreted studies like the WHI -The real numbers behind breast cancer risk—including how they compare to lifestyle factors like obesity and alcohol -What’s safe, what’s not, and how hormone therapy options vary by delivery method -The truth about oral contraceptives, vaginal estrogen, and testosterone -Emerging therapies on the horizon, including promising developments like Duavee and estetrol We also explore how genetic factors, such as BRCA status, impact the conversation, what screening looks like for high-risk women, and how shared decision-making can empower you in your menopause journey. This is not about one-size-fits-all answers—it’s about equipping you with nuanced, evidence-based knowledge so you can make informed decisions with confidence. Whether you’ve had breast cancer, have a family history, or feel paralyzed by the fear of “what if,” this episode is for you. Tune in, take notes, and let’s bring clarity to a subject that deserves more than headlines and half-truths.

   January 03, 2026·1h 38min
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