The body makes dozens of hormones that affect our health every day -sex hormones, thyroid, cortisol/stress hormones, melatonin etc. When hormones are out of balance, it can lead to symptoms like hot flashes, low libido, weight fluctuations, hair or skin changes, and many more. These symptoms can overlap since all hormones influence each other. That means, to get a full picture of hormonal health we need a broader lens.

Listen in today as we discuss Genova’s Endo+ Profile – The first of its kind. Endo+ is a modular panel of testing that offers the unique ability to assess saliva, blood, and urine simultaneously. This flexibility allows providers to create their own profiles to reveal insights and connections between sex hormones, thyroid function, adrenal health, melatonin rhythms, and estrogen metabolism – and Genova synthesizes all of that information for you! 

Today on The Lab Report:

• 2:20 Hormones are complicated and interconnected
• 5:25 The hormone pyramid
• 8:35 Endo+ Profile – the complete picture
• 10:50 Break it Down - saliva, blood, urine
• 13:20 Variables in choosing sample types
• 18:00 Endo+ Testing options and information synthesis
• 20:20 Anabolic/Catabolic balance
• 21:10 Estrogen Metabolism
• 22:15 Add-ons
• 23:05 Endo+ puts it all together

Additional Resources:

Endo+ Profile

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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

See omnystudio.com/listener for privacy information.

William Branum is a decorated Navy SEAL veteran with 26 years of active-duty service. Since leaving the military, William has dedicated his life to helping others through mentorship, coaching, speaking, and entrepreneurship. William’s expertise has been sought after by organizations ranging from small universities to Fortune 500 companies. He draws on his experiences to provide practical advice on how to cultivate a leadership style that inspires and motivates others, and how to develop the resilience needed to succeed in challenging environments. William founded the company ‘Naked Warrior Recovery’ to develop premium CBD products to support mental and physical recovery, through which he also supports several philanthropic causes for military and veterans’ mental health.

On today’s episode, William Branum explains how the wisdom and life lessons he gained from his Navy SEAL training can apply to each of us in our life transitions, workplace environments, and personal interactions. William also talks about his CBD products and promoting mental health.

Today on The Lab Report:

• 3:45 Meet the amazing William Branum and hear about his transition to civilian life
• 17:40 What is a Naked Warrior?
• 20:50 N.A.K.E.D., ego, and vulnerability
• 24:05 CBD products and Naked Warrior Recovery quality assurance
• 27:30 Cannabinoids, veterans’ mental health, and 22 to Zero
• 34:35 5 SEALS secrets to success and life lessons
• 39:30 Leadership and being the CEO of your life
• 51:00 The Fireball   

Additional Resources:

Free e-book "5 SEAL Secrets"

Naked Warrior Recovery

Naked Warrior Apparel

@william.r.branum   Instagram

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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Magnesium is a mineral that is crucially important to hundreds of biochemical reactions in our body. With gradual changes in soil, food processing, and the Standard American Diet, many of us just are not getting enough. So, what do we do? Dr. Robert Fredrickson has recently released a book all about this issue: Magnesium Answers: Unlocking the Secrets of Magnesium. As a functional medicine practitioner, he spent his career educating patients and doctors, but he also has a background as a product educator for major supplement companies. With that, Dr. Fredrickson is in a unique position to help us cut through the noise and understand the power of magnesium.

On today’s episode, Dr. Robert Fredrickson talks about all things magnesium – what it does, why we should care, how much do we need, and how do we choose among all of the different forms of magnesium supplementation?

Today on The Lab Report:

• 4:50 Meet Dr. Robert Fredrickson
• 9:30 How do we know if we’re not getting enough magnesium?
• 12:30 Magnesium in food and bioavailability
• 16:55 How much mag should we be getting?
• 18:15 Repleting mag and bowel tolerance
• 19:30 Measuring magnesium
• 22:10 Topical vs. IV vs. oral supplements
• 23:45 Types of magnesium supplementation
• 31:10 Magnesium toxicity, GI symptoms, Mag v. Calcium, IV mag
• 36:55 Fiber and magnesium connection
• 38:55 The Fireball      

Additional Resources:

Fredrickson Health Solutions

Magnesium Answers: Unlocking the Secrets of Magnesium

Fredrickson Health Show Podcast

Genova Connect  **PROMO CODE - TheLabReport20 for 20% off

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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Thanksgiving is a time to be mindful and reflect on our many blessings. During the holiday, many of us enjoy dinner with family and friends without stopping to consider the nutritional aspects of traditional dishes. Today, we discuss the important biochemical and nutritional benefits of Thanksgiving dinner items. We also talk about dealing with the stress of the holidays and the many reasons we are grateful.

Today on The Lab Report:

• 3:30 Turkey and tryptophan – is it a thing?
• 5:15 Cranberry sauce apologetics
• 7:45 Potatoes! - and the microbiome
• 10:35 Green bean casserole, (fake) mushrooms, and onions
• 13:15 Hollandaise sauce? Gravy? Stuffing? Ummm…moving on
• 14:10 Pumpkin is a fruit
• 15:20 Moderation and modifying your dinner
• 16:15 Movement and mindfulness
• 19:20 Gratitude and community – Patti & Michael give thanks

Additional Resources:

Michael's Famous Green Bean Casserole?

https://connect.gdx.net/

*PROMO CODE TheLabReport20  for 20% off**

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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

The immune system works tirelessly to maintain health and well-being. This formidable defense mechanism is comprised of a vast array of cells, tissues, proteins, and molecules that work together to identify and neutralize foreign invaders. The inflammation that ensues can be recognized by redness, pain, swelling, and heat. In order for this process to take place, the body needs to be able to identify what is ‘friend or foe’. But how? There are certain molecular patterns that our immune system recognizes as part of this surveillance and recognition. Some patterns are associated with pathogens - “pathogen-associated molecular patterns” (PAMPs). Others are associated with damaged cells (DAMPs) or lifestyle choices (LAMPs).  

In today’s episode, we do a quick refresher on adaptive and innate immunity. We also discuss some signaling molecules that trigger the inflammatory cascade – PAMPs, DAMPs, and LAMPs.

Today on The Lab Report:

• 3:40 Break it down – innate vs. adaptive immunity
• 6:40 Pathogen-associated molecular patterns (PAMPs), Pattern Recognition Receptors (PRRs)
• 10:25 Sterile inflammation: damage-associated molecular patterns (DAMPs)
• 14:30 Lifestyle-associated molecular patterns (LAMPs) & chronic inflammation
• 18:25 Question of the Day
  • How do we turn off the LAMPs?

Additional Resources:

Genova Connect   *PROMO CODE TheLabReport20 for 20% off*

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

When it comes to changing the way the world views mental health, one voice remains consistent, science-based, empathetic, and passionate. That’s Brendan Vermeire. Brendan is dedicated to advancing the science of mental health dysfunction through his research, teaching, writing, and speaking. Here in functional and precision medicine, we are always looking for the root cause of any dysfunction. However, Brendan reminds us that mental health can have several root causes that need to be addressed and many of us are falling short when it comes to treating patients with mental illness.

In today’s episode, we meet the amazing Brendan Vermeire. He talks about his passion for changing the way the world views mental health as we dive into some less obvious contributors and root causes. Brendan offers his approach to optimal mental well-being: metabolism, mindset, and the microbiome.

Today on The Lab Report:

• 4:20 Meet Brendan Vermeire and hear why he’s so passionate about mental health
• 9:20 Connection between physiology and mindset
• 11:10 Gut-brain axis and the role of the microbiome
• 13:45 Go-to practical tips for optimizing the gut for mental health
• 17:00 Let’s talk about Methylation!
• 22:35 The exposome and toxins in mood disorders 
• 27:00 Exercise, movement, and motivation
• 34:00 Meaning, purpose, and ‘the why’
• 36:40 MetabolicSolutionsLLC.com
• 37:50 The Fireball 

Additional Resources:

Metabolic Solutions

Brendan's Instagram -  @the_holistic_savage

Genova Connect  *PROMO CODE TheLabReport20 for 20% off*

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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

The topic of intestinal parasites and their prevalence is hotly debated in functional medicine. Furthermore, the increasing trend of people performing a ‘parasite cleanse’ of the GI tract can be dangerous. Parasites are diagnosed in the stool using microscopy, direct exam, and PCR – but even then, not all parasites should be treated. Some can cause significant illness, yet others are not invasive, self-limiting, and considered nonpathogenic.

In today's episode, we give a refresher course on gut parasites, discuss different ways to assess them, and introduce the topic of nonpathogenic parasites that don’t need to be treated.  

Today on The Lab Report:

• 3:50 Prevalence and transmission of parasites
• 6:45 What is a parasite? Are there nonpathogenic parasites?
• 8:10 3 main classes of parasites
• 10:20 Detecting parasites in the stool
• 13:10 Nonpathogenic parasites
  • Chilomastix mesnili, Endolimax nana, Entamoeba coli, Entamoeba dispar, Entamoeba hartmanni, Entamoeba polecki, Iodamoeba buetschlii

• 16:50 Potentially pathogenic parasites
• 19:25 Question of the Day
  • Why doesn’t Genova offer sensitivities for parasites on the GI Effects?

Additional Resources:

GI Effects Stool Profile

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

When it comes to assessing the microbiome, technology continuously evolves. With that, our understanding of the microbiome deepens. There is a lot of confusion out there regarding technology. Companies use marketing spin to lead you to believe the newest is the best when in fact, every technology has its strengths and weaknesses. No one method can capture the entire dynamic of the microbiome. Here at Genova, we use many methods to give you the most complete look at overall gut health.

Today we simplify the science behind laboratory assays used to study the microbiome – culture, qPCR, metagenomics, and transcriptomics. Every method has its advantages and disadvantages. We’re cutting through the confusion with no marketing spin, just the facts.

Today on The Lab Report:

• 3:30 So much confusion around laboratory methods - why should we care?
• 7:45 Culture technology is old but still so important
• 11:10 Conventional PCR and qPCR (aka Real-Time PCR)
• 15:40 Beware of these qPCR shortcomings
• 19:50 Next-Gen Sequencing
• 21:40 Metagenomics – not all labs are created equally!!
• 26:55 The vital role of taxonomy libraries
• 30:30 Transcriptomics and assessing RNA

Additional Resources:

GI Effects

Microbiomix

Genova Connect               PROMO CODE:  TheLabReport20 for 20% off

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Many clinicians learn about functional medicine and get very excited to start but just can’t figure out how to fit it into their practice or make the big leap away from conventional, insurance-based practice models. Dr. Michael Hilts figured it out. Dr. Hilts found out about the “Direct Primary Care” model which allowed him to fulfill his dream of bringing the best healthcare possible to his patients. In addition, his innovative strategies with outside imaging centers, laboratories, and pharmacies bring down the cost to patients in an almost unbelievable way! Could this be the answer to fixing our current healthcare system?

Today we meet Dr. Michael Hilts who introduces us to the Direct Primary Care (DPC) practice model which is rapidly spreading across the country. You’ll hear about innovative ways he uses DPC and other strategies to bring back the spirit of primary care, challenge the current healthcare paradigm, and turn it on its head!

Today on The Lab Report:

• 4:30 Meet Dr. Michael Hilts
• 5:50 What is Direct Primary Care and why did Dr. Hilts pivot?
• 12:20 Labs, medications, imaging = significant cost savings
• 16:10 The transition out of insurance-based conventional medicine
• 18:00 Incorporating functional medicine laboratory testing and success stories
• 24:00 Non-surgical sports medicine – ultrasound, prolo therapy, PFP
• 29:45 Work with Dr. Hilts
• 31:40 The Fireball

Additional Resources:

Hilts Direct Primary Care

Genova Connect  - (PROMO CODE: TheLabReport20 for 20% off GI Effects)

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

When it comes to sex hormones, progesterone is the unsung hero. It is actually the precursor to even making estrogen and testosterone. But progesterone is not just a precursor hormone. It is vital for maintaining pregnancy, helps with mood and sleep, works to help regulate the body’s water stores, and so much more.

In today’s episode, we unpack all of the important functions of progesterone, break down its many fates of metabolism, and talk about ways to optimize your hormonal balance.  

Today on The Lab Report:

• 3:30 What is progesterone and where is it made?
• 5:15 The cholesterol connection
• 6:55 Circulation and many fates of metabolism
• 12:50 Functions of progesterone
• 15:05 High progesterone levels – symptoms and causes
• 17:05 “Progesterone steal”
• 20:00 Low progesterone levels – symptoms and causes
• 24:00 Symphony of hormones and metabolism
• 25:30 Treating low progesterone, root-cause, synthetic vs. bio-identical BHRT

Additional Resources:

One Day Hormone Check

Rhythm Plus

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.