Building upon our previous discussion on optimizing the cortisol awakening response (ep. 89) for more productive mornings, we now shift our focus to the vital role of mitochondria in enhancing our energy and productivity in the new year. We'll explore the intricate structures within mitochondria, the mechanisms leading to dysfunction, and most importantly, uncover effective strategies, including supplements and dietary choices, to optimize mitochondrial function.
1. Introduction to Mitochondrial Dysfunction and Energy Production
- Overview of optimizing natural energy levels
- Factors leading to mitochondrial dysfunction and FATIGUE
2. Understanding Mitochondrial Structures
- Permeability and function
- Role in proton gradient
- Cristae and its significance
- Krebs cycle and NADH generation
- Mitochondrial DNA and ribosomes
3. Mechanisms of Mitochondrial Dysfunction
- Loss of inner mitochondrial membrane potential
- Alterations in the electron transport chain
- Reduced transport of critical metabolites
4. Ways to Improve Mitochondrial Function
- Preface for non-root cause issues
- Factors causing mitochondrial damage
- Example of ROS impact on ATP production
5. Supplements for Enhancing Mitochondrial Function
- Role in increasing glutathione levels
- Fatty acid transport and mitochondrial function
- Involvement in the electron transport chain
- Mitochondrial membrane phospholipids
- Lipid replacement therapy for repairing damage already done
6. Essential Minerals and Micronutrient Blood Panel
- Importance of essential minerals in mitochondrial metabolism
- The need for micronutrient blood panel
- Importance in the electron transport chain
- Precursors like NMN and NR for optimization
8. Other Modalities for Mitochondrial Support
- Mention of red light therapy
- Emphasis on dietary choices and antioxidant intake
- Importance of structural repair with lipid replacement therapy
9. Additional Tools and Research
- Urolithin A for stimulating mitochondrial recycling process
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