In this episode, we delve into the science behind peptide bioregulators, specifically focusing on Glandokort, a natural extract from the adrenal gland. We explore the unique characteristics and mechanisms of peptide bioregulators, highlighting their tissue-specific effects and role in gene regulation. Additionally, we provide an overview of the adrenal glands' anatomy and functions, and discuss how Glandokort may aid in normalizing adrenal gland protein synthesis in the context of some types of adrenal insufficiency.
Definition of peptides: Short chains of amino acids
Comparison of peptide bioregulators and other peptides (e.g., BPC-157)
Size and function of peptide bioregulators
Bioregulators penetrate the cell membrane AND the nuclear membrane Function of Peptide Bioregulators
Role in restoring organ balance
Tissue-specific effect Gene Regulation and Cellular Differentiation
Importance of gene regulation
Nuance of cell differentiation and gene expression
Today's focus: gene regulation impacting a cell's functional activity Mechanism of Bioregulators
Interaction with DNA and gene expression
Binding to histone proteins
Promotion of gene expression in tissue-specific cells History and Development of Peptide Bioregulators
Early isolation from animal tissues
Examples of tissues used for extraction
Development of the synthetic peptide bioregulators Natural vs. Synthetic Peptide Bioregulators
Availability of natural and synthetic supplements
Focusing on the natural extract of the adrenal gland: Glandokort
Location and function of adrenal glands
Division into cortex and medulla
Zona Glomerulosa: Production of mineralocorticoids (aldosterone)
Zona Fasciculata: Production of glucocorticoids (cortisol)
Zona Reticularis: Production of androgens
Production of catecholamines (adrenaline and noradrenaline)
Role in 'fight or flight' response
Description: Natural adrenal gland peptides
Function: Normalizing adrenal gland protein synthesis
Context of HPA-axis dysfunction or "adrenal fatigue"
Importance of working with a licensed medical professional
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