Siim Land Podcast

By Siim LandHealth & Fitness

Siim Land Podcast episodes

October 26, 2024#424 How to Prevent Heart Disease - Dr Paddy Barrett
Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland
Timestamps:
00:00 Intro

00:32 Bon Charge Sponsorship

01:20 Declining Heart Disease Rates

05:10 Biggest Risk Factors of Heart Disease

10:15 What Is Heart Disease and Atherosclerosis

13:55 When Does Atherosclerosis Begin

20:55 Biggest Risk Factors of Heart Disease

27:55 Role of Genetics in Heart Disease

31:50 High vs Low Lipids

39:40 Managing Your Risk Trajectory Over Time

45:30 Lp(a)

52:30 ApoB vs Cholesterol

57:20 Does HDL Reduce the Risk of Heart Disease

59:35 Homocysteine

01:02:55 Does Too Much Exercise Cause Atherosclerosis

01:09:55 Practical Steps to Heart Disease Prevention

01:15:30 Detecting Calcium in the Arteries

01:20:35 Calcified Hard Plaques vs Non-Calcified Plaques

01:22:45 At What Calcium Score Can You Get a Heart Attack
Dr Paddy Barrett Twitter: https://x.com/paddy_barrett
Dr Paddy Barrett Substack: https://paddybarrett.substack.com/
1 hr 27 min
October 17, 2024#423 Top Longevity Scientist Predicts Dramatic Life Extension by 2035 - Aubrey de Grey
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps:
00:00 Introduction

00:37 Twenty since Aubrey coined the Longevity Escape Velocity

11:13 When will we reach Longevity Escape Velocity

16:45 Slowing down aging vs regeneration

19:44 What breakthroughs we need for longevity escape velocity

24:00 Seven types of aging damage that needs to be repaired

24:37 Loss of cells and stem cells

33:57 Regenerating limbs and organs

36:10 Mitochondrial free radical theory of aging

41:15 Intracellular and Extracellular waste products

47:15 How far is gene therapy now?

49:15 Death resistant cells

53:52 Do you need long telomeres

57:15 Extracellular matrix stiffening and glycation

01:00:48 Biggest breakthroughs in the next 5 years

01:04:30 What to do to live until the longevity escape velocity
The Longevity Escape Velocity Foundation: https://www.levf.org/
Aubrey de Grey Twitter: https://x.com/aubreydegrey
1 hr 9 min
October 13, 2024#422 Cancer Biologist Shares the Science of Cancer Prevention - Dr Joe Zundell PhD
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps:
00:30 Introduction

00:50 What is cancer

04:30 Does everyone have cancer all the time?

06:30 When does cancer become lethal

11:30 Hallmarks of cancer

21:20 Senescent cells vs cancer cells

25:00 Evolutionary purpose of cancer

27:30 Cancer prevention

30:10 Ultra processed food and cancer risk

35:35 Organic vs non-organic food

38:40 What are carcinogens

45:10 Immune function and cancer

48:15 Meat and cancer

51:20 mTOR and cancer

01:02:20 Glucose, Warburg Effect and cancer

01:07:00 Ketones and cancer

01:11:00 Artificial sweeteners

01:16:40 Environmental toxins
Dr Joe Zundell YouTube channel: https://www.youtube.com/@dr.joezundell
Dr Joe Zundell Instagram: https://www.instagram.com/dr.joezundell/
1 hr 27 min
October 05, 2024#421 Supplements That HARM Your Heart - Q&A
Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland
Timestamps:
00:01 Supplements that are bad for the heart

08:45 Will we see someone live to 125

11:56 Bon Charge sponsorship

12:46 Maltodextrin in protein powder

13:59 Hyaluronic acid supplementation and cancer

15:32 Creatine reduces VO2 max

17:55 Limiting factor in losing visceral fat

20:45 Which disease am I most afraid of

25:13 Weighted stretching for muscle growth

28:00 Protein restriction and lifespan

32:22 How to train with joint pain

35:39 How much NAC for 60+

37:23 How to stimulate appetite

40:47 What's a good VO2 max for women
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF
44 min
September 28, 2024#420 The Weird Connection Between Omega 3 and Your Heart Health - Dr William Harris, PhD
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps:
00:37 Omega 3 Health Benefits as of 2024

03:50 Why Are Omega 3 Fats Beneficial

08:57 My New Book The Longevity Leap

09:15 Why Aren't Omega 3s Essential

09:57 What Is the Omega 3 Index

14:45 Is There Risk of Healthy User Bias

17:50 How High Omega 3 Index Is Optimal

26:28 How to Increase Omega 3 Index

29:38 Different Types of Omega 3 Supplements

32:40 Are Omega 3 Supplements Oxidized and Rancid

35:15 How to Choose an Omega 3 Supplement

40:15 Heart Disease and Omega 3s

46:25 Neurodegeneration and Omega 3s

48:00 Omega 6 Fats and Mortality

55:00 How Much Omega 6 Is Too Much

59:48 Omega 9 Fats

01:02:15 How to Store Omega 3 Supplements
1 hr 6 min
September 22, 2024#419 Dave Pascoe and Julie Gibson Clark Discuss Their Diet, Supplements and Exercise Routines
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps:
00:29 Introduction

02:43 Question 1: Death and longevity

11:23 Julie’s advice to Siim

12:58 Meeting likeminded people interested in longevity

17:33 Dave getting stem cells

19:33 Rejuvenation Olympics

22:18 How I share evidence

28:53 Longevity as a sport

40:58 How the Rejuvenation Olympics works

48:28 What’s the best biological age clock

53:58 Telomere length

58:31 How long can we make humans live

01:12:52 Panel about exercise routines

01:19:38 Panel about sleep

01:25:52 Panel about nutrition

01:36:44 Panel about supplements

01:46:44 Best low-hanging fruits
Adam the host's channel: https://youtube.com/@nopara73?si=7z6gKAq6s5vZTT_T
1 hr 52 min
September 14, 2024#418 Stem Cell Doctor Shares the Truth About Stem Cell Therapy for Anti-Aging
Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland
Timestamps:
00:30 Misconceptions about stem cell therapy

04:20 Different types of stem cells

07:10 Bon Charge sponsorship

07:55 Stem cells and aging

09:00 Studies about stem cell anti-aging effects

13:32 FDA regulations regarding stem cells

25:19 How Joy got into stem cells

36:39 Cost of stem cell therapy

43:40 Process of getting umbilical cord stem cells

49:45 Stem cell procedures

57:55 Finding reliable stem cell clinics

01:02:48 Joy Kong's clinic and content
Dr Joy Kong YouTube channel: https://www.youtube.com/@JoyKongMD/featured
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
1 hr 8 min
September 07, 2024#417 The Surprising Benefits of Nasal Breathing Nobody Tells You - Leigh Ewin
Code LEAP for 15% off the Longevity Leap Bundle: https://donotage.org/longevity-leap-bundle
Timestamps:
00:29 Leigh’s background

06:44 Health benefits of cold exposure and breathwork

09:44 Mammalian dive reflex

11:45 DoNotAge Longevity Leap supplement bundle

13:20 Benefits of breath holds

16:55 How long can you hold your breath for

20:30 Are there benefits to being able to hold your breath for long

25:56 Hyperventilation vs breath holds

34:46 Breathwork exercises for beginners

40:27 How to breathe correctly

45:00 Nasal breathing vs mouth breathing

52:00 How to breathe during exercise

54:45 Leigh’s new book
Leigh Ewin's new book: https://www.leighewin.com/leigh-events/p/re-spiritual-awakening-audiobook-pre-order
1 hr 2 min
September 01, 2024#416 Supplements That Damage Kidneys and Liver, mTOR and Longevity, How to Improve Skin Elasticity - Q&A
Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland
Timestamps:
00:01 Are Too Many Supplements Bad for Organs

03:46 How to Clear Caffeine From the Body

07:00 When Do I Think Longevity Escape Velocity Will Begin

11:05 Bon Charge Sponsorship

11:49 How to Improve Sleep

14:45 What Biomarker I Want to Improve

19:04 mTOR and Longevity

24:05 How to Increase HRV Besides Exercise

26:25 Do I Have Cheat Meals

27:46 Astaxanthin and Testosterone

29:02 Taking 35 Grams of Glycine Per Day

31:09 Thoughts on Pterostilbene for Longevity

32:25 Essential Supplements for Vegans

34:20 Cancer Prevention

35:42 How to Improve Skin Elasticity

36:43 Does Calorie Restriction Decrease Performance
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF
Join my next retreat at a longevity clinic: https://www.siimland.co/retreat
41 min
August 24, 2024#415 Longevity Doctor Shares Regeneration Protocol - Alexis Ortega MD
Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF
Order my new book: https://www.amazon.com/dp/B0CW1B2XM1
Timestamps
00:12 Alexis' background

03:00 What's available for regeneration currently

04:37 Alexis’ 3 step process for longevity medicine – Phase 1

09:30 The Longevity Leap Worksheet

10:09 Phase 2 - cleanup

12:35 Evidence for chelation therapies

13:58 Effects of senolytics

18:20 Phase 3 - regeneration

19:39 Exosomes and stem cells

28:09 Can exosomes extend lifespan

33:25 Peptides

39:08 Restoring melatonin levels

42:13 How many stem cells do you have

45:05 Why don't we live to 120

51:30 Can you remove plaque from arteries

56:10 What supplements Alexis takes

01:12:00 Diet and exercise

01:17:28 After the 3 phase plan
Alexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/
1 hr 27 min

About Siim Land Podcast

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Siim Land is an author, speaker, and consultant. He talks about optimizing health, performance, and longevity with different techniques and biohacking.