Following the last episode with Jeff Krasno on Good Stress, in this solo episode Dr. Sara unpacks the science behind toxic stress. She dives into how it embeds in the body, disrupts metabolism, accelerates aging, brain shrinkage, and chronic disease.

Dr. Sara shares compelling research on the connection between stress, Alzheimer’s, diabetes, autoimmunity, gut health, and perimenopause. She also explains why women are especially vulnerable and offers practical, evidence-based tools to help you measure, manage, and heal from toxic stress.

Whether you struggle with brain fog, anxiety, inflammation, autoimmunity, or hormone issues, this episode will help you understand the hidden role of stress—and what you can do to heal.

// RESOURCES // 

Find out your ACE Score by taking this quiz. 

Studies Linking High Cortisol to Brain Shrinkage, Memory Loss, and Alzheimer's Risk: 

• 2018 Study: The Framingham Heart Study
• 2024 Studies: 
• High Cortisol and the Risk of Dementia and Alzheimer’s Disease: A Review of the Literature
• Neuroinflammation, cerebrovascular dysfunction and diurnal cortisol biomarkers in a memory clinic cohort: Findings from the Co-STAR study
• How Can Early Stress Influence Later Alzheimer's Disease Risk? Possible Mediators and Underlying Mechanisms

// KEEP IN TOUCH WITH DR. SARA //

If you have a question, leave a voicemail at speakpipe.com/treated 

Follow on IG: @saragottfriedmd @treatedwithdrsara

Watch Treated on YouTube

Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.

 Produced by Dear Media. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Entrepreneur, author, and wellness advocate Jeff Krasno joins Treated for a deep and inspiring conversation about metabolic health, longevity, and the power of good stress. Jeff shares his personal health transformation—from battling pre-diabetes, weight gain, and brain fog to reversing metabolic dysfunction through lifestyle medicine.

In this episode, we explore: why balance is the foundation of health, the truth about pre-diabetes and why so many people are undiagnosed, the connection between childhood trauma, stress and chronic disease, and why social connection is the ultimate bio-hack for longevity. 

Jeff also unpacks key insights from his book Good Stress, explaining why we need more hormetic stress (cold, heat, fasting, exercise) to unlock metabolic flexibility, mental clarity, and emotional resilience. If you’re ready to take control of your health and embrace the right kind of stress, this episode is a must-listen!

// LEARN MORE FROM JEFF KRASNO //

Follow Jeff Krasno on Instagram @jeffkrasno

Purchase his book, Good Stress, here or wherever you buy books. 

Listen to Jeff’s Podcast, Commune with Jeff Krasno here. 

If you want to learn more about Jeff, head to jeffkrasno.com. 

// KEEP IN TOUCH WITH DR. SARA //

If you have a question, leave a voicemail at speakpipe.com/treated 

Follow on IG: @saragottfriedmd @treatedwithdrsara

Watch Treated on YouTube

Produced by Dear Media. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Schuyler Grant joins Treated with Dr. Sara Szal (formerly Dr. Sara Gottfried) for a raw, hilarious, and deeply honest conversation about hormones, menopause, and why midlife is the most powerful chapter of your life. Meet Schuyler Grant: Yoga teacher, retreat leader, and my co-conspirator in rebranding menopause. In this episode, we dive into 100+ symptoms of perimenopause, how to manage them, why the medical system is failing women, and why we need to rebrand menopause altogether. 

Schuyler and I also reveal what really happens at our sold-out Hot for Hormones retreats at Commune—and why women are flying across the world to be in the room. Plus, we explore the magic of Costa Rica’s Osa Peninsula and wrap up with a guided breathwork session that will shift your nervous system in real time.

If you’ve ever felt like your body is betraying you in midlife, this episode will change the way you think about aging, metabolism, and your next chapter.

// LEARN MORE FROM SCHUYLER GRANT //

Follow her on Instagram @schuylergrant.

Purchase Schuyler and Jeff’s book now, Good Stress here, or anywhere you find books.

Visit her website here.

// KEEP IN TOUCH WITH DR. SARA //

If you have a question, leave a voicemail at speakpipe.com/treated 

Follow on IG: @saragottfriedmd @treatedwithdrsara

Watch Treated on YouTube

Produced by Dear Media. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In part two of our conversation, Dr. Mindy Pelz and Dr. Sara Szal (formerly Dr. Sara Gottfried) dive even deeper—unpacking the hidden cost of success, the ways women betray themselves in pursuit of "having it all," and why midlife isn’t a crisis, it’s an initiation. We also explore the power of intuition, the patriarchy of medicine, and how to reclaim your identity beyond your career, your family, or your hormone levels. Settle in for an unfiltered, soul-stirring conversation you don’t want to miss.

// LEARN MORE FROM DR. MINDY PELZ //

Follow her on Instagram @dr.mindypelz and @theresetterpodcast.

Find links for her podcast, The Resetter Podcast, here.

Check out her website here.

// KEEP IN TOUCH WITH DR. SARA //

If you have a question, leave a voicemail at speakpipe.com/treated 

Follow on IG: @saragottfriedmd @treatedwithdrsara

Watch Treated on YouTube

 Produced by Dear Media. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Mindy Pelz joins Treated with Dr. Sara Szal (formerly Dr. Sara Gottfried) for a raw, hilarious, and deeply honest conversation about the hormonal rollercoaster of midlife and why so many high-achieving women feel lost at 35 (and 55). She opens up about her breaking point and what it took to admit that she was not okay. They reflect on why so many women struggle to ask for help, why self-care feels selfish, and the difference between “fixing” yourself and actually healing. From career burnout to navigating perimenopause like a boss, this episode is a must-listen for anyone who has ever put themselves last.

// LEARN MORE FROM DR. MINDY PELZ //

Follow her on Instagram @dr.mindypelz and @theresetterpodcast.

Find links for her podcast, The Resetter Podcast, here.

Check out her website here.

// KEEP IN TOUCH WITH DR. SARA //

If you have a question, leave a voicemail at speakpipe.com/treated 

Follow on IG: @saragottfriedmd @treatedwithdrsara

Watch Treated on YouTube

 Produced by Dear Media. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

At 35, after an Ivy League education, a career in “McMedicine,” and becoming a mother, Dr. Sara Szal (formerly Dr. Sara Gottfried) discovered the true power of hormones in healing. Now, as a precision medicine expert, she helps people reclaim their health through hormone balancing. In this episode, she reveals why hormones are the gateway to transformation—physically, mentally, and emotionally. Tune in to unlock the secrets of precision medicine and take control of your well-being.

// KEEP IN TOUCH WITH DR. SARA //

If you have a question, leave a voicemail at speakpipe.com/treated 

Follow on IG: @saragottfriedmd @treatedwithdrsara

Watch Treated on YouTube

 Produced by Dear Media. 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This is Treated, a new podcast with Dr. Sara Szal: Real talk. Real science. Real solutions. Each week you will leave with the tools you need to heal your mind, body, and soul so you can take your health into your own hands. Most people are trying to optimize, it’s in our nature. But we can’t “to-do-list” our way out of taking care of ourselves. This means health needs a perspective shift. On Treated, Dr. Sara sits down with experts in their fields and patients who have found holistic solutions to their health questions and created lasting transformation. Join us every Wednesday for new episodes.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.